National AI Awards 2025Discover AI's trailblazers! Join us to celebrate innovation and nominate industry leaders.

Nominate & Attend

Head of Clinical Pharmacology

The RFT Group
1 year ago
Applications closed

Related Jobs

View all jobs

Director of Clinical Biomarkers

Clinical Trials Officer

Clinical Trials Officer

Head of Clinical Operations

DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES

DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES

Job Description

Our client, a young Biotech company with an exciting pipeline, now have approval for a Head of Clinical Pharmacology role within their growing Clinical Science team, who will be based in either Ireland or the UK. This hire will oversee clinical pharmacology and PBPK consultants, ensuring appropriate PK, PD and PK-PD data analyses are conducted for each study/program to enable achievement of the company's objectives.

This hire will be the clinical pharmacology expert for the company and will be responsible for leading studies and projects within the project team, including design, oversight and evaluation of phase 1 studies. In addition, the position will include PBPK modelling activities to support early and late-stage development.

This hire will take clinical pharmacology responsibility for regulatory interactions e.g., pre-IND meetings, IND submissions, EoP2 meetings, pre-NDA meetings, NOA and MAA submissions.

The ideal candidate will be an experienced Clinical Pharmacologist operating at Director level in either Pharma or Biotech environment, with the attitude and ability to be effective in a lean, small company environment.

Responsibilities include:

· Provide leadership on all clinical pharmacology matters and support to project teams.

· Responsible for scientific quality of clinical pharmacology studies: design, implementation, analysis, interpretation, reporting and regulatory submission.

· Integrates clinical pharmacology knowledge with a broad understanding of and collaboration with related disciplines such as clinical, statistics, regulatory, nonclinical ADME, toxicology to support and impact development decisions. Partners with relevant stakeholders from discovery through commercialization.

· Key contributor (author/and or reviewer, as required) to high quality clinical pharmacology plans and content for global regulatory documents including protocols, investigator’s brochures, briefing documents, IND applications/annual reports, responses to regulatory queries, CSRs, and Clinical Pharmacology and Biopharmaceutics Summary Documents in NDAs/MAAs.

· Ensures adherence to agreed timelines and budgets to insure prompt and accurate execution of deliverables from clinical pharmacology studies and programs.

· Oversees clinical pharmacology and PBPK consultants.

· Maintains and establishes relationships and agreements with contract vendors.

· Presents data at scientific meetings and authors/ reviews manuscripts for submission to peer-reviewed journals as needed.

· Hands on reporting, analysis and interpretation of clinical study data.

· Supporting and presenting at study level meetings (Investigator Meetings, Data Monitoring Committee (DMC) meetings or others), as required.

Requirements include:

· PhD or PharmD degree with emphasis in clinical pharmacology and experience with clinical pharmacology studies is expected.

· Several years of scientific, strategic, and operational experience in planning, executing, reporting, and publishing clinical PK/PD programs in CNS pharma.

· Excellent understanding of ICH GCP and up-to date on regulatory requirements.

· Demonstrates good medical/scientific writing skills.

· Depth of pharmacokinetics, modelling and simulation techniques, principles of pharmacodynamics and PKPD analysis, concepts related to ADME, and bioanalytical methodologies/related regulations.

· Knowledge of principles of clinical data collection and reporting; ability to use systems and tools (e.g., EDC systems, Excel, etc.) for data collection, analysis, and reporting.

· Strong quantitative skills, including solid familiarity with statistical concepts.

· Ability to critically analyze problems and provide creative solutions.

· Scientific rigor in experimental design, study conduct, analysis, interpretation and communication of results.

· Ability to effectively communicate pharmacokinetic concepts to diverse audiences, including rationale for study designs.

· Contribute to the production and authoring of scientific documents with full attention to accuracy and consistency.

· Demonstrated ability to work effectively in a matrixed, team environment, manage multiple priorities and exercise sound judgment.

· Experience in the management of outsourced development programs

· Experience in working and influencing cross-functionally.

· Exhibits high motivation and high energy level, self-starter.

National AI Awards 2025

Subscribe to Future Tech Insights for the latest jobs & insights, direct to your inbox.

By subscribing, you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

10 Biotechnology Recruitment Agencies in the UK You Should Know (2025 Job‑Seeker Guide)

The UK’s biotech boom—fueled by the £650 million Life Sciences Vision Fund and rapid mRNA, cell & gene‑therapy adoption—continues to outpace talent supply. Lightcast reported +45 % year‑on‑year growth in UK adverts mentioning “CRISPR”, “GMP bioprocess” or “cell therapy” during Q1 2025. Yet only about 25,000 specialised biotech professionals work nationwide, while monthly live vacancies average 1,800–2,100. All data verified 22 July 2025; re‑audit quarterly for freshness.. Specialist recruiters remain critical for tapping stealth roles, benchmarking salaries and streamlining the lab‑tour interview gauntlet. We reviewed 60 + consultancies and kept only agencies with: A registered UK head office (Companies House). A dedicated Biotechnology / Life‑Sciences practice. At least five UK biotech roles advertised between March and June 2025. Below you’ll find a hiring‑landscape snapshot, a quick directory of 10 vetted agencies, salary medians, in‑demand skills, interview expectations, FAQs and next steps—mirroring our AI and quantum guides.

Biotech Jobs Skills Radar 2026: Emerging Tools, Platforms & Technologies to Learn Now

The UK biotechnology sector is entering a new era—fuelled by AI integration, synthetic biology, and next-gen diagnostics. With biotech investment breaking records and a surge in demand for skilled talent across R&D, biomanufacturing, and regulatory fields, it’s vital for job seekers to future-proof their skillsets. Welcome to the Biotech Jobs Skills Radar 2026—a forward-looking guide to the emerging tools, lab techniques, platforms, and digital skills driving hiring in the UK's biotechnology industry. This radar is updated annually to help students, researchers, and transitioning professionals stay competitive in a fast-changing landscape.

How to Find Hidden Biotechnology Jobs in the UK Using Professional Bodies like the RSB, BIA, BioIndustry Association & More

The UK biotechnology sector is thriving. From cutting-edge gene therapies and synthetic biology to bio-manufacturing and agricultural innovation, the demand for skilled biotech professionals continues to grow. Yet many of the best opportunities—particularly in early-stage companies, startups, and research-intensive roles—are never listed on conventional job boards. So where do these hidden biotech jobs live? Often, they’re shared through word-of-mouth, member networks, or professional communities—especially those associated with leading biotech institutions and associations. Whether you’re a graduate looking for your first role, a research scientist ready to move into industry, or a regulatory professional seeking your next challenge, joining the right professional bodies can give you exclusive access to job leads, collaborations, and insider opportunities. In this article, we’ll show you how to strategically leverage UK-based organisations such as the Royal Society of Biology (RSB), BioIndustry Association (BIA), and Biotech and Life Sciences Networks to uncover hidden jobs and build a long-term, sustainable career in biotechnology.