DMPK Lead - growing biotech

hays-gcj-v4-pd-online
London
1 year ago
Applications closed

Your newpany
Hays Life Sciences have been exclusively retained by a VC backed biotech that has already raised tens of millions of pounds of funding and is using its novel platform technology to develop innovative medicines for areas of unmet need, allowing you to have a significant impact on patients.Thepany has a high-performing and innovative atmosphere, driven by the highly experienced leadership team which has an excellent track record of developing therapeutics.They are going into their next phase of growth and are looking to further build up their R&D teams within chemistry and biology with the addition of an experienced DMPK Lead to focus on leading drug discovery & development projects.This is ideally a full-time position (but could be part-time for the right candidate), with hybrid working based out of their site in London, though there is significant flexibility for remote working.

Your new role
This is a permanent position, reporting into the VP of Drug Discovery, and working closely with a variety of internal colleagues and external stakeholders and vendors.The role is hybrid, requiring some time on site, and is focused on leading thepany’s DMPK efforts as they develop the next generation of small molecule therapeutics focused on protein degradation.Major responsibilities will include a mix of (but aren’t limited to):

Acting as a technical lead on drug development and late-stage discovery projects, working from hit ID, through Lead Optimisation & in-vivo/IND studies to the clinic Design, implement and oversee thepany’s DMPK strategy, including significant input into their project portfolio and candidate progression Support experimental & project design and technical troubleshooting with colleagues in other departments Provide support on aspects such as PKPD modelling orpound profiling for dose prediction Identify requirements from internal stakeholders and help to develop new approaches Presenting results to senior leadership and other stakeholders, eg within medicinal chemistry or biology teams Liaising with external CROs / vendors, eg for outsourced in-vivo work



What you'll need to succeed
As well as strongmunication skills for dealing with internal collaborators and stakeholders, you should have:A degree (with MSc or PhD preferred) in biology, chemistry, biochemistry, pharmacology or a similar Life Sciences discipline, or equivalent experienceA strong track record in small molecule drug metabolism, bioanalysis, pharmacokinetics gained in a Pharma, Biotech or CRO environment and familiarity with principles of PKPD modelling, eg using Phoenix or WinNonLinExperience working on diverse drug discovery & development projects, deliveringpounds to pre-clinical and clinical development. Experience of building mechanistic disease models, and / or quantitative systems pharmacology expertise, is highly desirable.Proven experience of using cutting edge approaches topound profiling and prediction of human dose and PK parameters.An excellent knowledge of all aspects of ADMET and PK to influence experimental design and data interpretation across a range of projects.Experience of working on projects at all stages of drug discovery from hit to lead to the clinic.Worked with external partners, ie CROs, and managed the outsourcing of in-vivo (and preferably in-vitro) studies.Good time management skills, a proven ability to form close and effective relationships with colleagues at all levels (both internal and in partner organisations) and excellent written and verbalmunication skillExperience of working on protein degradation / PROTACS / molecular glue projects would be a distinct advantage.

What you'll get in return
You'll get the chance to make a significant impact on thepany's drug discovery and development projects, taking on project leadership for a number of different aspects within DMPK as they develop the next generation of medicines and progress these towards the clinic.Thepany are relatively open on salary bands depending on the skills of the personing in and the benefits package associated with the role is quite generous.

Subscribe to Future Tech Insights for the latest jobs & insights, direct to your inbox.

By subscribing, you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Jobs

CSL Behring Jobs UK: Careers, Salaries, Locations & How to Get Hired

CSL Behring is one of the world’s leading biopharmaceutical companies specialising in plasma-derived therapies, recombinant proteins, gene therapy, vaccines, and rare disease treatments. If you’re a UK job seeker looking for a career with real purpose, strong scientific standards, and long-term progression, CSL Behring roles can be an excellent fit, especially if you have experience in biotech, pharma manufacturing, quality, engineering, supply chain, clinical operations, regulatory, pharmacovigilance, or commercial. This guide is written for UK candidates who want to understand what CSL Behring jobs typically involve, which roles to target, where opportunities may be based, what skills recruiters look for, and how to tailor your application to stand out.

Careers

How Many Biotechnology Tools Do You Need to Know to Get a Biotech Job?

If you are trying to break into biotechnology or progress your career, it can feel like the list of tools you are expected to know is endless. One job advert asks for PCR, another mentions cell culture, another lists bioinformatics pipelines, automation platforms or GMP systems. LinkedIn makes it worse, with people sharing long skills lists that make you wonder if you are already behind. Here is the reality most biotech employers will not say out loud: they are not hiring you because you know every tool. They are hiring you because you understand biological systems, can work accurately and safely, follow protocols, interpret results and contribute reliably to a team. Tools matter, but only when they support those outcomes. So how many biotechnology tools do you actually need to know to get a job? The answer depends on the role you are targeting, but for most job seekers it is far fewer than you think. This article breaks down what employers really expect, which tools are essential, which are role-specific, and how to focus your learning so you look employable rather than overwhelmed.

Jobs

What Hiring Managers Look for First in Biotechnology Job Applications (UK Guide)

Hiring managers in biotechnology do not start by reading your CV word for word. They scan for credibility, relevance and risk. In a regulated, evidence-driven sector like biotech, the first question is simple: is this person safe, competent and genuinely capable of contributing in this environment? Whether you are applying for roles in research, manufacturing, quality, regulatory, clinical, bioinformatics or commercial biotech, the strongest applications make the right signals obvious in the first 10–20 seconds. This in-depth guide explains exactly what hiring managers in UK biotechnology look for first, how they assess CVs, cover letters and portfolios, and why capable candidates are often rejected. Use it as a practical checklist before you apply.

🍪 We use cookies to enhance your browsing experience on our website. By continuing to use this site, you consent to the use of cookies as described in our Cookie Policy. You can review our Cookie Policy for more information.