Director of Bioinformatics

Warman O'Brien
Cambridge
1 week ago
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Director of Bioinformatics – Confidential Biotech – Cambridge Area


A leading and well-funded biotechnology company based in the Cambridge area is seeking aDirector of Bioinformaticsto spearhead the development of a cutting-edge computational biology platform. This is a rare and exciting opportunity to lead thefull-scale buildoutof a bioinformatics function at the forefront of biologics discovery.


The Opportunity

This hands-on leadership role is ideal for someone passionate about the application ofAI and structure-guided designto therapeutic antibody engineering. You will be instrumental in shaping the computational strategy from the ground up, with significant creative freedom, and will collaborate closely with internal R&D and selected CROs.

This is aconfidential searchon behalf of a company operating at the intersection of antibody innovation and non-traditional protein scaffolds. The organisation offers a dynamic and entrepreneurial environment backed by experienced founders and top-tier investors.


Key Responsibilities

  • Lead the full-scale buildout of the company's bioinformatics infrastructure.
  • Develop and implement AI-driven approaches to therapeutic biologics design.
  • Drive collaboration across cross-functional teams and external research partners.
  • Take ownership of CRO selection and partnership management.
  • Contribute to team expansion by hiring and mentoring junior staff.


About You

  • PhD (or equivalent industry experience) in Computational Biology, Structural Bioinformatics, Protein Engineering, or a related field.
  • Proven experience with protein structure modelling, antibody engineering, or biologics design.
  • Proficiency with Python, R, and modern bioinformatics/ML tools.
  • Strong track record in applying generative models (e.g. AlphaFold, RFdiffusion).
  • Demonstrated leadership capability and a desire to remain hands-on.
  • Experience working with biologics isessential.


What’s on Offer

  • Highly competitive salary and benefits package.
  • Equity participation in a rapidly growing organisation.
  • Opportunity to define and lead a pivotal function in an innovative biotech.


If you are interested and would like to find out more please don't delay as we are anticipating providing an initial shortlist to the client by the end of May.

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