Antibody Discovery and Engineering Scientist

BioTalent
Slough
6 days ago
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Overview


The role will be based full time onsite in slough for a 12 month initial contract, starting in June and is an ideal role for scientists who are looking to start working in industry.


Join world leaders in antibody drug discovery and development. This unique opportunity allows you to work with a cutting-edge Antibody Discovery team, helping shape the delivery of next generation antibody therapeutics.

You'll be part of a dynamic team of scientists developing and validating new sequence-based and structure-based antibody design approaches, including antibody hit identification, sequence optimization, and in silico de novo antibody design. This laboratory-based role requires molecular biology and microbiological expertise, with antibody discovery or protein engineering experience being highly advantageous.



Responsibilities

  • Discover therapeutic monoclonal antibodies for patients suffering with serious disease
  • Utilize yeast display technology for human antibody discovery and optimization
  • Design and perform selections using synthetic display libraries to support antibody discovery projects
  • Prepare and analyze next generation sequencing (NGS) libraries
  • Collaborate with computational scientists to apply AI/Deep learning and structure-based approaches
  • Develop new methodologies in antibody display and engineering
  • Deliver results against timelines across project teams
  • Present experimental data at cross-functional meetings


Requirements

  • PhD (or equivalent) with molecular biology and protein biochemistry knowledge, ideally in antibodies
  • Experience with in vitro display libraries for discovery, affinity maturation, or protein engineering
  • Knowledge of biochemical characterization techniques (flow-cytometry, SPR, BLI)
  • Computational skills including molecular visualization and NGS data analysis
  • Strong attention to detail and critical data analysis abilities
  • Proven ability to meet deadlines
  • Excellent communication skills

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