Jobs in Stoke-on-trent

Spotlight

Senior Clinical Trial Case Manager

This role involves leading safety data review and pharmacovigilance activities within clinical trials, ensuring compliance with international regulations such as GxP. The individual will mentor team members, manage CAPAs, support regulatory inspections, and contribute to safety reporting and risk management. Key responsibilities include MedDRA coding, safety data analysis, and developing pharmacovigilance procedures to support global regulatory requirements.

CSL

On-site Permanent

Spotlight

Senior Computational Chemist, LNP Design

This role involves leading the computational design of lipid nanoparticles for nucleic acid delivery, using chemical and biophysical principles, AI tools, and molecular simulations. You will work closely with the experimental team to translate computational insights into testable strategies and refine formulations iteratively.

CureAge Therapeutics London, ENG, United Kingdom

Hybrid Permanent Part-time

Senior Engineer, CSV Validation

This role involves end-to-end ownership of computerised system validation (CSV) for GxP-regulated systems used in the manufacturing and testing of advanced CAR-T cell therapies. The engineer will author and execute validation documentation, ensure compliance with international regulations (e.g. FDA 21 CFR Part 11, EU GMP Annex 11), manage change controls and CAPAs, and support regulatory inspections. The position requires strong technical writing, cross-functional collaboration, and expertise in GAMP 5 and data integrity within a biopharmaceutical context.

Autolus Stevenage, United Kingdom

Associate Director - Global Regulatory Affairs (Oncology Therapeutic Group)

This role involves developing and executing global and regional regulatory strategies for oncology assets, ensuring optimal labelling and approvals while maintaining compliance. You will collaborate with cross-functional teams to shape development plans and regulatory interactions across multiple regions, with a focus on clear thinking, collaboration, and a patient-first mindset.

GSK Stevenage, United Kingdom

Associate Director - Global Regulatory Affairs (Oncology Therapeutic Group)

This role involves developing and executing global and regional regulatory strategies for oncology assets, ensuring optimal labelling and approvals while maintaining compliance. The Associate Director will collaborate with cross-functional teams to shape development plans and regulatory interactions across multiple regions.

GSK

TCTU Portfolio Trial Manager (BE-GENOMICS)

This role involves managing clinical trials, including providing support on approval processes, trial management, recruitment strategies, and data quality. The position is part of the Tayside Clinical Trials Unit (TCTU) and focuses on both new and established drug and complex intervention trials, with a lead role in the BE-Genomics trial.

University of Dundee Dundee, United Kingdom £37 – £46 pa

On-site Contract Part-time

Senior Research Associate, Bioanalytical & Molecular Assays

This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.

Moderna Oxford, United Kingdom

Hybrid Permanent

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

This role involves developing, validating, and executing ligand-binding and cell-based assays to support mRNA medicine development. The candidate will generate pharmacodynamic and immunogenicity data in a regulated GcLP environment, manage critical reagent characterization, and contribute to clinical sample testing using Watson LIMS. The position emphasizes scientific rigor, regulatory compliance, and collaboration within a high-performance team advancing novel bioanalytical assays.

Moderna Oxford, United Kingdom

Hybrid Permanent

PhD Studentship: Engineering protein nanocages for biotechnology applications

This PhD project focuses on engineering bacterial and human ferritins as nanocage platforms for encapsulating small molecules, peptides, and proteins. The research will involve optimizing encapsulation methods, investigating substrate and electron transfer, and developing applications in biocatalysis and therapeutics/diagnostics. The project offers extensive training in protein purification, bioanalytical methods, spectroscopy, and microscopy.

University of East Anglia Norwich, South East England, United Kingdom £21 pa

Contract

Analyst, Quality Control, Microbiology

This role involves performing routine environmental monitoring, water sampling, and microbiological testing (including sterility, bioburden, and endotoxin) for mRNA products in a GMP-regulated manufacturing environment. The analyst will support method transfers, data review, investigations, and compliance activities while working closely with internal teams and contract laboratories. Emphasis is placed on digital workflows, data integrity, and adherence to cGMP standards.

Moderna Oxford, United Kingdom

Principal Engineer, Drug Product

The Principal Engineer, Drug Product will lead the development of global engineering standards for drug product processes, including filling, inspection, packaging, and labeling. They will manage capital projects, ensure regulatory compliance, and drive innovation in manufacturing technologies across Moderna’s global network.

Moderna United States £142,500 – £256,500 pa

Principal Engineer, Drug Product

The Principal Engineer, Drug Product will lead the development of global engineering standards for sterile drug product processes, including filling, inspection, packaging, and labeling. They will manage capital projects, ensure regulatory compliance, and drive innovation in manufacturing technologies across Moderna’s global network.

Moderna

(Fixed Term) Manufacturing Associate I

Operate and maintain mRNA vaccine production equipment in compliance with cGMP and safety standards, executing manufacturing processes, troubleshooting equipment and digital systems, and supporting quality documentation and continuous improvement initiatives. Work within a cross-functional team to ensure timely batch release and operational excellence in a fast-paced, highly regulated environment.

Moderna Oxford, United Kingdom

On-site Temporary

(Fixed Term) Manufacturing Associate I

Operate production equipment for mRNA vaccine manufacturing in compliance with cGMP and safety standards. Perform routine maintenance, support deviation investigations, and contribute to continuous improvement in a highly regulated, technology-driven environment. Work collaboratively with QA and cross-functional teams to ensure timely batch disposition and operational excellence.

Moderna

On-site Temporary