Jobs in Stoke-on-trent

Senior Engineer, CSV Validation

This role involves end-to-end ownership of computerised system validation (CSV) for GxP-regulated systems used in the manufacturing and testing of advanced CAR-T cell therapies. The engineer will author and execute validation documentation, ensure compliance with international regulations (e.g. FDA 21 CFR Part 11, EU GMP Annex 11), manage change controls and CAPAs, and support regulatory inspections. The position requires strong technical writing, cross-functional collaboration, and expertise in GAMP 5 and data integrity within a biopharmaceutical context.

Autolus Stevenage, United Kingdom

Senior Research Associate, Bioanalytical & Molecular Assays

This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.

Moderna Oxford, United Kingdom

Hybrid Permanent

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

This role involves developing, validating, and executing ligand-binding and cell-based assays to support mRNA medicine development. The candidate will generate pharmacodynamic and immunogenicity data in a regulated GcLP environment, manage critical reagent characterization, and contribute to clinical sample testing using Watson LIMS. The position emphasizes scientific rigor, regulatory compliance, and collaboration within a high-performance team advancing novel bioanalytical assays.

Moderna Oxford, United Kingdom

Hybrid Permanent

Senior Clinical Development Medical Director

This role involves leading clinical strategy and execution for cardiovascular/stroke medicine programs, with responsibility for trial design, regulatory documentation, and cross-functional collaboration. The Senior Clinical Development Medical Director will guide global teams, interpret complex clinical data, and contribute to safety and development decisions across the drug lifecycle. Expertise in anticoagulation and outcome trials is key, along with strong leadership in a matrix environment.

Novartis London, United Kingdom

Senior Clinical Development Medical Director

This role involves providing clinical leadership and strategic medical input for cardiovascular/stroke drug development programs, including designing and executing global clinical trials. The Senior Clinical Development Medical Director will act as the global medical lead, interpreting clinical and safety data, contributing to regulatory submissions, and collaborating with cross-functional teams and external stakeholders. The position plays a key role in shaping clinical strategy and ensuring patient safety across the development lifecycle.

Novartis

Laboratory Technician - Plant Cell Culture

This role involves hands-on support for plant tissue and cell culture experiments within a cutting-edge research environment focused on sustainable agriculture and food production. The technician will prepare media, maintain cultures, monitor growth and contamination, and ensure aseptic conditions, contributing to scalable plant-based solutions. Close collaboration with researchers and automation specialists supports reproducible, high-quality scientific workflows in a state-of-the-art lab setting.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent