Jobs in Stoke-on-trent

Senior Engineer, CSV Validation

This role involves end-to-end ownership of computerised system validation (CSV) for GxP-regulated systems used in the manufacturing and testing of advanced CAR-T cell therapies. The engineer will author and execute validation documentation, ensure compliance with international regulations (e.g. FDA 21 CFR Part 11, EU GMP Annex 11), manage change controls and CAPAs, and support regulatory inspections. The position requires strong technical writing, cross-functional collaboration, and expertise in GAMP 5 and data integrity within a biopharmaceutical context.

Autolus Stevenage, United Kingdom

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based therapeutic development. The scientist will lead assay development for clinical programmes using platforms like ELISA, MSD, and cell-based methods, ensuring regulatory compliance and robust data generation. The position emphasizes collaboration across multidisciplinary teams and integration of digital tools and AI to advance Moderna's pipeline.

Moderna Oxford, United Kingdom

On-site Contract

Senior Research Associate, Bioanalytical & Molecular Assays

This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.

Moderna Oxford, United Kingdom

Hybrid Permanent

Consulting Engineer - Medical Device Development

This role involves acting as a technical advisor in early-stage business development for medical device innovation, bridging scientific expertise with commercial strategy. You'll engage with clients to understand their challenges, collaborate with engineers and scientists to develop technically sound proposals, and help convert ideas into market-ready solutions. The position supports cutting-edge projects such as implantable sensors, laser-based therapies, and non-invasive surgical technologies.

Newton Colmore Cambridge, Cambridgeshire, United Kingdom

Hybrid Permanent

Production Process Engineer

Production Process EngineerCastle Donington, DerbyshireAre you passionate about continuous improvement and process efficiency? Do you want to play a key role in helping a growing employee-owned manufacturing business achieve its lean, quality and productivity goals?We are looking for an experienced...

Medstrom Diseworth, Leicestershire, DE74 2QD, United Kingdom £48,000 pa

Senior Clinical Development Medical Director

This role involves leading clinical strategy and execution for cardiovascular/stroke medicine programs, with responsibility for trial design, regulatory documentation, and cross-functional collaboration. The Senior Clinical Development Medical Director will guide global teams, interpret complex clinical data, and contribute to safety and development decisions across the drug lifecycle. Expertise in anticoagulation and outcome trials is key, along with strong leadership in a matrix environment.

Novartis London, United Kingdom

Senior Clinical Development Medical Director

This role involves providing clinical leadership and strategic medical input for cardiovascular/stroke drug development programs, including designing and executing global clinical trials. The Senior Clinical Development Medical Director will act as the global medical lead, interpreting clinical and safety data, contributing to regulatory submissions, and collaborating with cross-functional teams and external stakeholders. The position plays a key role in shaping clinical strategy and ensuring patient safety across the development lifecycle.

Novartis