Jobs in Leeds

Research Technician in Molecular Virology

This role involves supporting research into arbovirus biology, focusing on chikungunya virus and related flaviviruses. The technician will use molecular and cell biology techniques such as PCR, cloning, RNAseq, and infectious clone systems to study viral genome regulation in human and mosquito cells. The work contributes to identifying antiviral targets within a multidisciplinary team at a leading UK research university.

University of Leeds Leeds, Northern England, United Kingdom £29 – £33 pa

Permanent

Head, PV and Regulatory QA

This role leads the global quality and compliance function for pharmacovigilance (PV) systems, ensuring adherence to international regulations and internal standards across clinical safety, regulatory affairs, and medical affairs. The position combines strategic oversight with hands-on operational leadership, including audit strategy, inspection readiness, deviation and CAPA management, and cross-functional GxP guidance. It requires deep technical expertise in PV processes and strong leadership to drive quality across global teams and third-party vendors.

CSL

Head, PV and Regulatory QA

Leads global pharmacovigilance and regulatory quality assurance, ensuring compliance with GVP, ICH, and regulatory standards across clinical safety, medical affairs, and regulatory affairs. Designs audit strategies, manages inspections, and oversees deviation management, CAPA, and change control systems. Provides cross-functional GxP expertise and drives continuous improvement in PV quality systems.

CSL

A

Senior Director, Semantic Platform Enablement

Leads the design and enterprise-wide enablement of AstraZeneca’s semantic platform, establishing foundational models, canonical entities, and reusable standards to ensure consistent, machine-readable data meaning across platforms and domains. Drives adoption by aligning semantic architecture with business use cases, integrating structured and unstructured data, and enabling interoperability for AI and agentic systems. Operates in a federated model with cross-functional collaboration across data, product, and technology teams.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

SERM Scientific Director

Leads safety evaluation and risk management for GSK's oncology assets in clinical development, providing scientific expertise to assess and communicate safety risks globally. Works cross-functionally to shape safety strategy, support regulatory submissions, and ensure patient protection. Focuses on signal detection, risk assessment, and strategic decision-making in a matrix environment.

GSK £111,750 – £186,250 pa

On-site Permanent

Senior Director, Portfolio Integration Lead - Hematology

Leads cross-programme scientific strategy and integration across GSK’s oncology portfolio, with a focus on hematology. Provides expert guidance on disease biology, biomarker strategies, and clinical development innovation across multiple assets. Champions data-driven decision-making, trial innovation, and external engagement to align portfolio direction and accelerate development.

GSK Stevenage, United Kingdom US$242,250 – US$403,750 pa

Hybrid Permanent

A

Executive Director, Strategy, Oncology R&D

This role involves leading the global Oncology R&D strategy at AstraZeneca, shaping therapeutic area priorities by integrating clinical, scientific, and commercial insights. The individual will advise senior leadership on portfolio optimization, investment decisions, and strategic trade-offs, using rigorous analysis to drive innovation and patient impact. It requires influencing without authority, aligning cross-functional teams, and maintaining strategic rigor across complex R&D landscapes.

AstraZeneca London, United Kingdom US$270,222 – US$405,332 pa

On-site Permanent

Study Grants Manager

The Study Grants Manager translates clinical trial protocols into accurate grant plans and fair market value assessments, supporting efficient site activation and budget forecasting. This role involves close collaboration with global study teams, country organizations, and vendors to optimize cost models and operational efficiency across clinical trials. It requires strong analytical skills, expertise in clinical development processes, and advanced use of tools like GrantPlan and MS Excel.

Novartis London, United Kingdom £49,140 – £91,260 pa

Hybrid Permanent

Translational Medicine Expert – Gastroenterology, Associate Director

This role involves leading early-phase clinical development (Phase 1 and 2) of novel gastroenterology therapies, with a focus on inflammatory bowel disease (IBD). The Translational Medicine Expert will design clinical development plans, serve as medical lead for trials, and collaborate closely with research, biomarker, and late-phase development teams. The position requires strong scientific leadership, engagement with key opinion leaders, and active involvement in regulatory interactions.

Novartis London, United Kingdom £67,900 – £126,100 pa

Sr. Manager, Operational Strategy Lead

This role involves developing and implementing end-to-end clinical supply operational strategies for Pfizer's global clinical programs, focusing on packaging, labelling, and distribution. The Operational Strategy Lead works cross-functionally to ensure patient-centric, compliant, and efficient delivery of clinical supplies, while driving continuous improvement and digital transformation in supply chain processes. Key responsibilities include risk management, stakeholder collaboration, and strategic planning to support clinical trial timelines and patient needs.

Pfizer

Medical Insights, Data Analyst Senior Manager

This role involves conducting ad hoc and exploratory data analysis to answer complex business and medical questions that cannot be addressed through existing platforms. The Senior Manager partners with global Medical Insights teams to translate ambiguous queries into actionable analytical approaches, validate datasets, and deliver clear, decision-ready insights. A key differentiator is the protected time for innovation—testing new data sources, AI methods, and proof-of-concept analyses to inform the strategic evolution of Pfizer’s global analytics platform.

Pfizer United States US$124,400 – US$207,400 pa

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs England

Hybrid Permanent

Research Leader (DMPK), Cambridge, MA

Lead DMPK strategy for drug discovery projects using an AI-first approach, integrating quantitative pharmacology and ADME data to guide candidate selection. Collaborate with chemistry, pharmacology, and machine learning teams to optimise molecule design and advance predictive models. Contribute to regulatory documentation and drive innovation in human PK prediction and biotransformation understanding.

Isomorphic Labs Cambridge, United Kingdom

Senior Computational Biologist – Early Discovery Immunology

A Senior Computational Biologist will drive target discovery in immunology and inflammatory diseases by integrating multi-omics data (phenomics, transcriptomics, genomics, proteomics) to nominate and validate novel therapeutic targets. The role involves developing computational methods, collaborating with cross-functional teams, and translating complex analyses into actionable drug discovery programs using Recursion’s AI-driven platform.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent