24 jobs for “Protein Engineer”
Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa
Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.
CureAge Therapeutics London
Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.
Latent Labs London
Customer-facing engineering role bridging frontier generative biology models and pharma/biotech clients. You own end-to-end deployments, building production-grade API integrations, data pipelines and model-serving infrastructure, often embedded on-site with partners, and feed customer insights back into product and research teams.
Evotec Macclesfield
Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.
Latent Labs London
Architect novel generative models to design functional proteins, working in an interdisciplinary team of ML researchers, protein engineers and biologists. Split roughly 90/10 between building and evaluating models against wet lab results and self-development, with heavy emphasis on data pipelines, cloud training and production-quality code.
Ellison Institute of Technology Oxford £40,000 pa
Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.
Ellison Institute of Technology Oxford
Develops and optimises high-throughput enzyme assays to characterise plant protein variants from AI-assisted design and evolutionary discovery. Works with computational scientists, automation engineers and roboticists to build scalable protein expression, purification and biochemical characterisation pipelines, informing protein engineering and crop yield decisions.
Evotec Abingdon
Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.
Nuclera Cambridge
Full-stack engineer building customer-facing cloud and instrument software plus internal tools supporting in-house protein screening services. Owns features end to end, from gathering requirements with biologists and stakeholders through technical design, implementation and testing across backend, frontend, dev-ops and QA.
UCL London £68,284 – £76,244 pa
Develops and leads an AI-driven research programme in biomolecular design and molecular interactions, spanning protein-ligand, protein-protein and protein-nucleic acid systems. Combines structural biology, biophysics, quantitative biology and machine learning, while teaching computational biology and biomolecular design at undergraduate and postgraduate level, including a new MRes in AI for Bioscience.
Roche Welwyn
Builds physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Works in a small-molecule team within AI for Drug Discovery, creating synthetic quantum-mechanics datasets and deployable pipelines that feed molecular-design tools across Roche, with a strong publication and open-source focus.
Roche Basel, Switzerland
Build physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Work in a small-molecule team within AI for Drug Discovery, creating synthetic QM datasets and deployable, scalable pipelines that feed molecular-design tools across Roche, alongside computational and experimental scientists.
Basecamp Research London
Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.
Basecamp Research London
Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.
Nuclera Cambridge
Formulate, dispense and quality-control reagents for a protein discovery platform, operating lab equipment such as pipettes, centrifuges and UPLC systems. The role covers batch documentation, inventory management via ERP and troubleshooting production deviations, working closely with R&D, QA and Supply Chain in a fast-paced lab environment.
IQVIA Cambridge
A senior scientific leadership role shaping and delivering a drug discovery strategy, driving adoption of AI-assisted design, predictive modelling, automation and computational science across a diverse portfolio. The post-holder mentors multidisciplinary teams spanning biology, chemistry, protein design, pharmacology and translational sciences, and acts as a scientific ambassador in client engagements, proposals and partnerships.
Bicycle Therapeutics Cambridge
Handles processing, quality control and distribution of research samples from internal and external sources, uploading data to LIMS and storing materials in an automated compound management store. Prepares assay-ready samples using automated liquid handlers and manual workflows, and supports the team's transition towards automated workflows.
