Biotechnology Jobs

• Norwich
• On-site
• £21,805 pa
• Entry level
• Contract

Investigate why sexually antagonistic genes persist, using Drosophila to identify consistent loci and validate their sex-specific fitness effects via CRISPR-Cas9 allele swaps. Combines bioinformatics, genome engineering and sequencing, with training across evolutionary genetics, statistics and functional genomics at Norwich Research Park.

CRISPR-Cas9 · Long-read Sequencing · Single-cell Transcriptomics

• Exeter
• £21,805 pa
• Entry level
• Contract

An interdisciplinary PhD studentship combining computational genomics at Exeter with stem-cell biology and CRISPR editing at Cambridge. The student will analyse whole-genome sequencing data from large multi-ancestry cohorts, integrate genetic signals with epigenetic maps and AI tools like AlphaGenome, and build iPSC-derived visceral and subcutaneous adipocyte models to functionally test prioritised regulatory variants.

AlphaGenome · DNANexus · Flow Cytometry +1

• Exeter
• Entry level
• Contract

Computational PhD project using cell-free DNA sequencing to infer placental gene activity and dissect how genetic variants linked to adverse pregnancy outcomes affect placental function. The student develops tools to map nucleosomal footprints, integrates them with single-cell RNA-seq markers and GWAS summary statistics, and may generate new plasma data.

scRNA-seq · cfDNA Sequencing · GWAS

• Norwich
• £21,805 pa
• Entry level
• Contract

A four-year PhD project using engineering biology to develop bacterial and human ferritin nanocages for encapsulating small molecules, peptides and proteins, with applications in biocatalysis and therapeutics. The work spans protein purification, bioanalytical methods, spectroscopy, mass spectrometry and microscopy, targeting enzymes such as hydrogenase and targeted molecular delivery. Based in the Le Brun lab at UEA's School of Chemistry, Pharmacy and Pharmacology.

Ferritin

• Newcastle upon Tyne
• £21,805 pa
• Entry level
• Contract

Investigates the molecular mechanisms of liver dysfunction in childhood POLG-related mitochondrial disease, focusing on Alpers-Huttenlocher syndrome. Uses quantitative untargeted proteomics and immunohistochemistry on donated post-mortem liver tissue, and generates hepatic organoids from patient-derived iPSCs for disease modelling and therapeutic screening. Based in the Newcastle Mitochondrial Research Group with a placement at the University of St Andrews.

iPSCs

• Manchester
• £21,805 pa
• Entry level
• Contract

A four-year PhD studentship developing chemically engineered proximity-labelling probes as tuneable sensors of local cellular environments. The student will synthesise and characterise probe libraries, then evaluate them in living cells using biochemical assays, advanced fluorescence imaging and super-resolution microscopy, with selective proteomic analysis to map molecular networks.

Proximity Labelling · Fluorescence Imaging · Super-Resolution Microscopy +1

• Manchester
• £21,805 pa
• Entry level
• Contract

A four-year PhD studentship developing molecular-scale quantum sensors to detect cancer biomarkers via their magnetic rather than fluorescent signatures, aiming to map molecular markers on cancer cells at high resolution. The project addresses weak-signal limitations of conventional fluorescence microscopy and involves close collaboration with the main supervisor, Dr Keerthi.

Quantum Sensors

• London
• Hybrid
• Entry level
• Temporary

A one-year PhD fellowship within an International Regulatory Affairs team, supporting development programs and marketed products. The fellow helps build and implement regulatory strategy, prepares and submits applications to local health authorities under supervision, and reviews regulatory intelligence to keep submissions compliant. Based at the London headquarters with hybrid or on-site working options.

• Sheffield
• £39,560 – £41,885 pa
• Entry level
• Contract

Contribute to a research programme analysing explanted polymeric medical devices, investigating how implant degradation, tissue responses and patient-specific factors drive complications. Establish experimental and sample-handling workflows, develop lab methods to characterise tissue and immune responses, and collaborate with academic, clinical, regulatory and patient partners including Sheffield Teaching Hospitals and Cambridge.

• Coventry
• On-site
• £36,320 – £46,970 pa
• Entry level
• Contract

Postdoctoral role in the Clostridial Cell Biology Group, leading molecular biology and experimental evolution work on vancomycin resistance in Clostridioides difficile. Collaborates with biochemists, bioinformaticians and clinical microbiologists across Warwick, Sheffield, Manchester and Leeds, and involves supervising PhD and masters students.

• Oxford
• On-site
• £40,178 – £48,700 pa
• Entry level
• Contract

Conducts research characterising crosslinked proteins and lipids under a Wellcome Trust-funded grant, using proteome and lipidome methods including sample preparation, LCMS and data analysis. Manages project administration, guides junior researchers and students, and contributes to reports, publications and external seminars.

LC-MS · nanoLC-MS

• Keele
• £39,560 – £48,337 pa
• Entry level
• Contract

A postdoctoral research associate role delivering the insect-focused laboratory components of a consortium project on a planthopper-vectored bacterial plant disease. The postholder investigates vector ecology and transmission biology using insect rearing, bioassays, EPG analysis and molecular techniques such as PCR and qRT-PCR, with occasional travel within the UK and Europe.

Electrical Penetration Graph · Bioinformatics

• Slough
• Hybrid · 3 days in office
• £37 – £50 ph
• Contract

Process, analyse and interpret omics data from clinical portfolio studies to uncover biological mechanisms, treatment effects and safety signals. Develop analysis pipelines using state-of-the-art tools, document reproducible code for patient-level data, and write reports and scientific publications. Requires strong bulk and single-cell RNAseq expertise, R, HPC/Unix and Docker skills.

Docker · DNAnexus

• Oxford
• On-site
• £40,178 – £48,700 pa
• Entry level
• Contract

Join a Gates Foundation-funded programme developing nanopore-based sensing platforms to detect volatile organic compounds in biological samples, part of the multidisciplinary Decoding Olfaction collaboration. The role combines chemical biology and biophysics to advance single-molecule sensing, with the goal of enabling personalised and continuous health monitoring. Multiple fixed-term postdoc positions are available in a collaborative academic and industrial environment.