Latest Isomorphic Labs Jobs

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs England

Hybrid Permanent

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

Lead translational strategies for oncology and immunology programs by designing in vivo pharmacology and PK/PD studies to validate AI-designed drug candidates. Bridge computational predictions with experimental validation through CRO partnerships and biomarker-driven approaches. Drive preclinical data generation to inform clinical trial design and regulatory filings.

Isomorphic Labs England

Hybrid Permanent

General Application - Register Your Interest

This is a general interest application for roles at Isomorphic Labs, an AI-driven drug discovery company. Candidates may be considered for positions including Software Engineers, ML Researchers, Computational Chemists, and Technical Project Managers. The role involves interdisciplinary collaboration to advance AI models for rational drug design and digital biology, within a culture emphasising curiosity, bravery, determination, and teamwork.

Isomorphic Labs United Kingdom

Hybrid Permanent

Clinical Program Manager, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, coordinating cross-functional global teams and external vendors. This role involves managing timelines, budgets, risks, and stakeholder communication, while leveraging AI-driven insights to accelerate development. The position emphasizes integrated project planning and operational leadership to ensure efficient, high-probability clinical advancement.

Isomorphic Labs England

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

This role involves leading the clinical development of oncology drug candidates derived from AI-driven insights, translating them into actionable trial strategies, and ensuring scientific and regulatory rigor. The Medical Director will act as the primary medical monitor, guide cross-functional teams, and represent the company in interactions with regulators and key opinion leaders. The position emphasizes patient safety, protocol compliance, and strategic input from discovery through clinical proof-of-concept.

Isomorphic Labs England

Hybrid Permanent