Biotechnology Jobs

Spotlight

Associate Director, Biostatistics

This role leads the statistical strategy for clinical development programs, overseeing study design, data analysis, and regulatory submissions. The individual will guide biostatistical input across trials, interact with regulatory authorities, and ensure accurate reporting of results. Collaboration with cross-functional teams and oversight of internal or outsourced programming efforts are key aspects of the position.

CSL

Hybrid Permanent

Spotlight

Senior Clinical Trial Case Manager

This role involves leading safety data review and pharmacovigilance activities within clinical trials, ensuring compliance with international regulations such as GxP. The individual will mentor team members, manage CAPAs, support regulatory inspections, and contribute to safety reporting and risk management. Key responsibilities include MedDRA coding, safety data analysis, and developing pharmacovigilance procedures to support global regulatory requirements.

CSL

On-site Permanent

Clinic Operations, Partnership Manager

This role involves managing the partnership and operational delivery of EIT's Oxford Clinic, including liaison with the clinical services partner, stakeholder communication, and financial oversight. The position focuses on building, launching, and growing innovative healthcare services.

Ellison Institute of Technology Oxford, United Kingdom

On-site Contract

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Scientist, Genetic Assays

This role involves designing and executing biochemical and molecular biology assays to support pharmacokinetic/pharmacodynamic analysis. Responsibilities include developing robust mRNA-based bioanalytical capabilities, troubleshooting scientific issues, and collaborating with external partners. The position also offers opportunities to work with Generative AI and digital tools to enhance scientific workflows.

Moderna Oxford, United Kingdom

Scientist, Genetic Assays

This role involves developing and executing biochemical and molecular biology assays to support pharmacokinetic/pharmacodynamic analysis. Responsibilities include assay development, data analysis, and collaboration with external partners, while staying current with scientific literature and regulatory guidelines.

Moderna

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Senior Computational Biologist – Early Discovery Immunology

A Senior Computational Biologist will drive target discovery in immunology and inflammatory diseases by integrating multi-omics data (phenomics, transcriptomics, genomics, proteomics) to nominate and validate novel therapeutic targets. The role involves developing computational methods, collaborating with cross-functional teams, and translating complex analyses into actionable drug discovery programs using Recursion’s AI-driven platform.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Senior Computational Biologist - Early Discovery Oncology

Drive target discovery and validation in precision oncology by integrating multimodal biological data (phenomics, transcriptomics, genomics, proteomics) to identify novel therapeutic targets. Collaborate with cross-functional teams to develop scalable computational methods and build compelling data packages that advance drug programs. Develop criteria for target nomination and support early translational strategies using AI-powered platforms.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based therapeutic development. The scientist will lead assay development for clinical programmes using platforms like ELISA, MSD, and cell-based methods, ensuring regulatory compliance and robust data generation. The position emphasizes collaboration across multidisciplinary teams and integration of digital tools and AI to advance Moderna's pipeline.

Moderna Oxford, United Kingdom

On-site Contract

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based clinical development programmes. The scientist will lead assay development—including ADA, nAb, PK, and PD assays—using platforms like ELISA, MSD, and cell culture, while ensuring regulatory compliance and contributing to Moderna's expanding capabilities in Harwell. The position emphasizes collaboration across multidisciplinary teams and integration of digital and AI-enabled tools to enhance data interpretation and decision-making.

Moderna

On-site

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs England

Hybrid Permanent

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

Lead translational strategies for oncology and immunology programs by designing in vivo pharmacology and PK/PD studies to validate AI-designed drug candidates. Bridge computational predictions with experimental validation through CRO partnerships and biomarker-driven approaches. Drive preclinical data generation to inform clinical trial design and regulatory filings.

Isomorphic Labs England

Hybrid Permanent

Head of Medicinal Chemistry, Drug Design, London

Lead and strategically guide a team of 25 medicinal chemists in redefining drug discovery through deep integration with AI and machine learning. Shape the scientific direction of projects from hit identification to candidate nomination, while fostering collaboration across computational design, biology, and pre-clinical development teams. Drive innovation by challenging traditional paradigms and embedding an AI-first culture across the chemistry function.

Isomorphic Labs London, United Kingdom

On-site Permanent

Associate Director, Computational Biology – Early Discovery

Lead a team of computational biologists to identify and validate novel oncology targets using integrated phenomics, transcriptomics, genomics, and proteomics data. Develop and scale methods for target discovery in oncology and immunological diseases, collaborating closely with biologists, data scientists, and engineers. Drive data strategy and present findings to stakeholders to advance drug discovery programs.

Recursion United Kingdom

On-site Permanent

Bioanalytical Lead, London

Lead the development and execution of bioanalytical strategies for a diverse portfolio of AI-designed therapeutics, including small molecules, biologics, and ADCs. Design and validate PK, PD, and immunogenicity assays, manage global CROs, and integrate bioanalytical data into AI models to refine drug discovery. Play a key role in IND-enabling studies and cross-functional preclinical development in a hybrid London-based role.

Isomorphic Labs London, United Kingdom

Hybrid Permanent