3 jobs for “Protein Engineer”
Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa
Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.
CureAge Therapeutics London
Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.
EMBL-EBI Saffron Walden £3,452 pm
Designs and develops software and APIs for the UniProt protein data services and website, serving a global scientific community. Also handles design, maintenance and monitoring of the website's cloud infrastructure, with a focus on scalability, well-tested code and distributed big-data processing. Works in a dynamic interdisciplinary team of engineers and bioinformaticians alongside biologists.
EMBL-EBI Saffron Walden
Develops FAIR infrastructure connecting proteomics evidence (XL-MS, CF-MS, AP-MS) with structural restraints, predicted structures and integrative models. Builds data models, APIs, conversion and validation tools with PRIDE and wwPDB, extending community standards for structural interactomics and linked deposition workflows.
Vertex Pharmaceuticals Oxford
A 12-month laboratory-based industrial placement within the Structural Biology & Biophysics department, working at the interface with Biology on a collaborative project. The role involves membrane protein preparation and reconstitution into lipid-based model systems, functional characterisation using electrophysiology, and interpreting biochemical and biophysical data to support early drug discovery.
