Biotechnology Jobs

41 jobs for “Protein Engineer”

Results

CureAge Therapeutics logo
Featured

Senior Computational Chemist, LNP Design

Last week

CureAge Therapeutics London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Hybrid Permanent Part-time
Alloy Therapeutics UK Ltd logo
Featured

Scientist I – Molecular Biology

3 days ago

Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

On-site Permanent

Forward Deployed AI Engineer

8 months ago

Latent Labs London

Customer-facing engineering role bridging frontier generative biology models and pharma/biotech clients. You own end-to-end deployments, building production-grade API integrations, data pipelines and model-serving infrastructure, often embedded on-site with partners, and feed customer insights back into product and research teams.

Hybrid Permanent

Senior Scientist I

2 weeks ago

Evotec Macclesfield

Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.

On-site Permanent

Machine Learning Scientist

4 months ago

Latent Labs London

Architect novel generative models to design functional proteins, working in an interdisciplinary team of ML researchers, protein engineers and biologists. Split roughly 90/10 between building and evaluating models against wet lab results and self-development, with heavy emphasis on data pipelines, cloud training and production-quality code.

Hybrid Permanent
Ellison Institute of Technology logo

Postdoctoral Research Fellow (Liu Lab) - Generative Biology Institute

5 months ago

Ellison Institute of Technology Oxford £40,000 pa

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

On-site Permanent
Ellison Institute of Technology logo

Scientist, Enzymology - Plant Biology Institute

Last month

Ellison Institute of Technology Oxford

Develops and optimises high-throughput enzyme assays to characterise plant protein variants from AI-assisted design and evolutionary discovery. Works with computational scientists, automation engineers and roboticists to build scalable protein expression, purification and biochemical characterisation pipelines, informing protein engineering and crop yield decisions.

On-site Permanent

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Principal Medical Scientist (Biopharmaceutical)

2 weeks ago

ISR Recruitment Oxford £520 – £532 pd

Lead a laboratory-based immunology team, designing in vitro pharmacology assays and coordinating in vivo efficacy studies with CROs to advance biologic therapies for autoimmune diseases. Involves target identification, ex vivo profiling, and cross-functional work with protein engineering, biomarkers and translational medicine, plus IND documentation and publications.

On-site Contract

VP Head of Therapeutics Design

2 weeks ago

Evotec Abingdon

Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.

On-site Permanent

Software Engineer

Last week

EMBL-EBI Saffron Walden £3,452 pm

Designs and develops software and APIs for the UniProt protein data services and website, serving a global scientific community. Also handles design, maintenance and monitoring of the website's cloud infrastructure, with a focus on scalability, well-tested code and distributed big-data processing. Works in a dynamic interdisciplinary team of engineers and bioinformaticians alongside biologists.

Hybrid Contract

Senior Software Engineer - Cloud

3 weeks ago

Nuclera Cambridge

Full-stack engineer building customer-facing cloud and instrument software plus internal tools supporting in-house protein screening services. Owns features end to end, from gathering requirements with biologists and stakeholders through technical design, implementation and testing across backend, frontend, dev-ops and QA.

Hybrid Permanent

Bioinformatician – Structural Proteomics & Integrative Modelling

2 weeks ago

EMBL-EBI Saffron Walden

Develops FAIR infrastructure connecting proteomics evidence (XL-MS, CF-MS, AP-MS) with structural restraints, predicted structures and integrative models. Builds data models, APIs, conversion and validation tools with PRIDE and wwPDB, extending community standards for structural interactomics and linked deposition workflows.

Hybrid Contract

Lecturer / Associate Professor in Artificial Intelligence for Biomolecular Design & Molecular Interactions

5 days ago

UCL London £68,284 – £76,244 pa

Develops and leads an AI-driven research programme in biomolecular design and molecular interactions, spanning protein-ligand, protein-protein and protein-nucleic acid systems. Combines structural biology, biophysics, quantitative biology and machine learning, while teaching computational biology and biomolecular design at undergraduate and postgraduate level, including a new MRes in AI for Bioscience.

Hybrid Permanent
Roche logo

Machine Learning Scientist - Quantum Chemistry

4 months ago

Roche Welwyn

Builds physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Works in a small-molecule team within AI for Drug Discovery, creating synthetic quantum-mechanics datasets and deployable pipelines that feed molecular-design tools across Roche, with a strong publication and open-source focus.

Hybrid Permanent
Roche logo

Machine Learning Scientist - Quantum Chemistry

4 months ago

Roche Basel, Switzerland

Build physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Work in a small-molecule team within AI for Drug Discovery, creating synthetic QM datasets and deployable, scalable pipelines that feed molecular-design tools across Roche, alongside computational and experimental scientists.

Hybrid Permanent

Market Product Lead

Last week

Basecamp Research London

Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.

On-site Permanent
Isomorphic Labs logo

Senior Research Investigator, (Biologics Pharmacology), London

Last week

Isomorphic Labs London

Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.

Hybrid