Biotechnology Jobs

• Grimsby
• US$188,100 – US$313,500 pa
• Director

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and statisticians. Combines inverse-problem modelling, scientific ML and statistical methods to support decisions from exploratory research through clinical development.

• USA - Pennsylvania - Upper Providence
• US$188,100 – US$313,500 pa
• Director

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic mathematical models of disease and drug action to inform trial design and MIDD strategy. Collaborates with biologists, clinicians, pharmacometricians and AI/ML teams, and represents the function on internal advisory boards.

• Reading
• Mid-level

Monitors clinical trial sites across the UK, performing selection, initiation, monitoring and close-out visits in line with GCP and sponsor requirements. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains TMF/ISF documentation. Dedicated to a single sponsor within IQVIA's cFSP model.

Microsoft Word · Microsoft Excel · Microsoft PowerPoint

• Manchester
• Mid-level

Monitors oncology clinical trial sites through selection, initiation, monitoring and close-out visits, ensuring compliance with GCP and ICH guidelines. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains Trial Master File documentation. Works within IQVIA UK's multi-sponsor Site Management team, with travel to sites required.

Trial Master File · Investigator's Site File

• Oxford
• On-site
• Senior

Provides hands-on MS&T engineering expertise across drug substance manufacturing and label, packaging and final-storage operations at the Harwell site. Leads technology transfer, process start-up, validation, continued process verification and troubleshooting, authoring protocols and reports as an individual contributor. Works cross-functionally with Manufacturing, Quality and Supply Chain, with on-call or shift coverage as required.

SAP · VEEVA · DeltaV +4

• Cambridge, United States
• Hybrid · 3 days in office
• Lead

Lead DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments while integrating DMPK, PD and toxicology data for dose and safety predictions. Work closely with AI/ML platform teams to optimise computational ADME models and author regulatory sections, in a hybrid Cambridge, MA role.

Python · R

• Cambridge, United States
• Hybrid · 3 days in office
• Lead

Lead the safety assessment strategy for small molecule and biologic drug discovery projects from inception to regulatory submission, designing screening cascades and mechanistic experiments. Partner with machine learning researchers to build predictive toxicology models and manage CRO relationships for outsourced wet-lab data generation, while mentoring junior team members.

KNIME · Python

• Oxford
• Hybrid
• Mid-level
• Permanent

Research Scientist role in the Molecular Simulations and Design team, combining generative models, physical simulation and experimental data to accelerate biomolecule design, initially enzymes. Involves developing methods such as Boltzmann samplers, long-timestep molecular dynamics, machine-learned interatomic potentials and flow matching/diffusion, with full-stack work from pre-training to design-build-test loops.

• Coventry
• On-site
• £36,320 – £46,970 pa
• Entry level
• Contract

Postdoctoral role in the Clostridial Cell Biology Group, leading molecular biology and experimental evolution work on vancomycin resistance in Clostridioides difficile. Collaborates with biochemists, bioinformaticians and clinical microbiologists across Warwick, Sheffield, Manchester and Leeds, and involves supervising PhD and masters students.

• London
• On-site
• Mid-level
• Permanent

Own the full post-training lifecycle for biological foundation models, from alignment strategy to production deployment. Design pipelines that adapt general-purpose models to therapeutic contexts, build validation frameworks linking model improvements to biological ground truth, and run experiments end-to-end on distributed GPU infrastructure. Collaborate with ML infrastructure and biology teams and contribute to open-source tooling.

OpenTargets · helical-package · GPU

• Oxford
• On-site
• £36,360 – £42,434 pa
• Entry level
• Contract

Supports an experimental programme building predictive models of cells, maintaining mammalian cell systems and running workflows such as endogenous protein tagging, CRISPR perturbation, optical pooled screening, live-cell imaging and proteomics. Works with computational and experimental researchers, generating engineered cell models and analysing data within a collaborative lab.

CRISPR · Flow Cytometry · Immunoblotting +4

• London
• On-site
• Mid-level

Develops and optimises therapeutic delivery formulations, designing lab experiments to assess stability, physicochemical properties and in vitro performance. Works in a multidisciplinary biotech team, characterising formulations analytically and supporting scale-up and tech transfer towards manufacturing. Distinct for its blend of formulation science, experimental development and translational research.

• Oxford
• On-site
• £40,000 pa
• Entry level
• Permanent

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

OrthoRep

• London
• US$228,000 – US$304,000 pa
• Mid-level

Designs and prototypes new agent harness capabilities such as context compaction, tool interfaces, long-horizon planning and multi-agent swarms, and invents new RL environments that turn scientific workflows and simulators into training signal. Builds end-to-end pipelines converting papers, codebases and lab protocols into validated, versioned synthetic environments integrated with the training loop.

Ray · Modal · vLLM +3

• London
• US$176,000 – US$304,000 pa
• Mid-level

Design and prototype scientific evaluations and RL environments for frontier LLMs, turning papers, codebases and lab protocols into validated, versioned training environments at scale. Work spans reward shaping, data collection and integration with the training loop, requiring strong Python prototyping and large-scale data pipeline experience.

Ray · Modal · vLLM +3