Latest Biologics Jobs

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

Lead or contribute to drug discovery programs using AI-first approaches, integrating computational chemistry with machine learning to design novel therapeutics. Guide project strategy from hit identification through candidate selection, while collaborating closely with ML scientists and cross-functional teams. Help shape and refine AI models for drug design, with opportunities to lead teams and drive innovation in a dynamic, interdisciplinary environment.

Isomorphic Labs Cambridge, United Kingdom

Senior Clinical Trial Manager, Cambridge, MA

The role involves end-to-end management of clinical trials within a fast-paced, AI-driven drug discovery environment. The Senior Clinical Trial Manager will lead cross-functional teams, oversee trial start-up through close-out, ensure compliance with ICH/GCP standards, and integrate AI innovations into clinical operations. Key responsibilities include vendor and budget management, clinical documentation, data oversight, and supporting regulatory readiness and audits.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Medical Director, Oncology Clinical Development - Hematology

This role involves leading medical oversight in oncology clinical development, focusing on hematology and clonal myeloid disorders. The Medical Director will guide study design, ensure patient safety, interpret clinical data, and collaborate with cross-functional teams and external experts. It is a physician-led position embedded in clinical strategy with a strong emphasis on real-world impact and regulatory engagement.

GSK Stevenage, United Kingdom PLN 455,250 – PLN 758,750 pa

Medical Director, Oncology Clinical Development - Hematology

This role involves providing medical leadership in oncology clinical development, with responsibilities spanning study design, medical monitoring, safety oversight, and data interpretation. The Medical Director will integrate physician-level insights into clinical trials, collaborate with cross-functional teams and external experts, and contribute to regulatory submissions and scientific communications. The position emphasizes patient-centered decision-making and real-world impact in cancer treatment innovation.

GSK £222,750 – £371,250 pa

Hybrid Permanent

Head of Medicinal Chemistry, Drug Design, London

Lead and strategically guide a team of 25 medicinal chemists in redefining drug discovery through deep integration with AI and machine learning. Shape the scientific direction of projects from hit identification to candidate nomination, while fostering collaboration across computational design, biology, and pre-clinical development teams. Drive innovation by challenging traditional paradigms and embedding an AI-first culture across the chemistry function.

Isomorphic Labs London, United Kingdom

On-site Permanent

ML Research Engineer, London

Develop and optimise cutting-edge AI models at the intersection of machine learning and drug discovery, translating research into scalable, production-ready systems. Work on foundational models like Diffusion networks, Transformers, and GNNs, building robust infrastructure and data pipelines while collaborating closely with scientists. Focus on advancing a digital biology platform to accelerate rational drug design across multiple therapeutic areas.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Scientist (Applied LLMs), London

A Research Scientist focused on applying Large Language Models to drug discovery, working in interdisciplinary teams to develop novel AI-driven approaches for biological and chemical challenges. The role involves advancing LLM techniques such as post-training, reasoning, tool-use, and alignment within a cutting-edge AI research environment. Collaboration with scientists and engineers is central to developing predictive models that accelerate rational drug design.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Research Scientist (Machine Learning), London

A Research Scientist in Machine Learning will develop novel deep learning models and algorithms to advance drug discovery at digital speed. Working in an interdisciplinary environment, they will apply cutting-edge ML techniques to complex biological and chemical problems, iterating closely with domain experts. The role involves leading high-ambition research projects, scaling training frameworks, and shaping the technical direction of AI-driven drug design.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Staff Software Engineer (Inference Platform), London

This role involves leading the reliability and scalability of AI/ML infrastructure for biotech applications, focusing on GPU/TPU systems, workload orchestration, and inference services. The engineer will overhaul monitoring, improve CI/CD stability, and ensure robust platform performance to support cutting-edge drug discovery research. Close collaboration with research and applied ML teams is central to the role.

Isomorphic Labs London, United Kingdom

On-site Permanent

Software Engineer (TechOps), London

This role involves building and managing cloud infrastructure and DevOps tooling to support AI-driven drug discovery. You'll work across research, development, and production environments using GCP, Kubernetes, and Infrastructure as Code, collaborating closely with scientists, ML researchers, and engineers. The focus is on creating scalable, secure, and automated systems that accelerate scientific innovation in a fast-moving, interdisciplinary environment.

Isomorphic Labs United Kingdom

Hybrid Permanent

Associate Director, Clinical Supply Chain, Cambridge, MA

This role involves leading end-to-end clinical trial material planning, vendor management, packaging, labeling, inventory management, and global distribution. You will work closely with Clinical Operations and the Clinical Development team to ensure seamless clinical trial execution and compliance with regulatory standards.

Isomorphic Labs Cambridge, United Kingdom

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Security Engineering Manager, London or Lausanne

As a Security Engineering Manager, you will lead and scale a high-performing team responsible for securing Isomorphic Labs' AI-driven drug discovery platform. You'll define the technical security roadmap across cloud infrastructure, IAM, secure SDLC, and security monitoring, while enabling rapid innovation for ML researchers and drug discovery teams. The role involves pioneering AI-first security architectures, leading transformational projects, and acting as a key liaison within the Alphabet/Google ecosystem.

Isomorphic Labs United Kingdom

Associate Director, Clinical Program Management, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, coordinating cross-functional global teams and managing timelines, budgets, and vendor partnerships. The role leverages AI and emerging technologies to drive efficient clinical development with a focus on high-probability outcomes. It involves strategic oversight of CROs and collaborators while ensuring alignment between clinical objectives and company goals.

Isomorphic Labs England

Hybrid Permanent

General Application - Register Your Interest

This is a general interest application for roles at Isomorphic Labs, an AI-driven drug discovery company. Candidates may be considered for positions including Software Engineers, ML Researchers, Computational Chemists, and Technical Project Managers. The role involves interdisciplinary collaboration to advance AI models for rational drug design and digital biology, within a culture emphasising curiosity, bravery, determination, and teamwork.

Isomorphic Labs United Kingdom

Hybrid Permanent