Jobs in Cambridge

Director, Translational Medicine, Oncology, Cambridge, MA

Lead the development and execution of translational medicine strategies for oncology programs, integrating AI-driven insights to inform clinical trial design and biomarker development. Collaborate with cross-functional teams to translate preclinical findings into clinical applications and advance companion diagnostics. Play a key role in shaping the scientific direction of early-stage drug development using cutting-edge methodologies and digital biology approaches.

Isomorphic Labs Cambridge, United Kingdom

Medical Director-Oncology Clinical Development - GI

This role involves leading medical monitoring and safety oversight for gastrointestinal (GI) oncology clinical trials within GSK’s global development programme. The Medical Director provides physician-level expertise in study design, data interpretation, and regulatory engagement, ensuring patient safety and clinical integrity across phases I–III. Working within a cross-functional matrix team, the role integrates medical insight into clinical strategy and collaborates with external experts and investigators to advance innovative cancer therapies.

GSK

Hybrid Permanent

Associate Director Predictive Agentic Target Biology

Lead the development and application of predictive computational models and agentic workflows to evaluate the tractability and safety of biological targets for drug discovery. Integrate multimodal data including genomics, proteomics, and functional screens to inform target prioritisation and mechanism of action. Collaborate with biologists, data scientists, and project teams to translate biological questions into robust, reproducible pipelines that guide go/no-go decisions in early drug development.

GSK Stevenage, United Kingdom

Hybrid Permanent

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12 Month University Industrial Placement Student (UIPS): Digital Health Strategy

This role involves supporting the development of digital health and AI strategies within Evinova, AstraZeneca’s health-tech subsidiary. You'll contribute to real-world initiatives in clinical development, conduct market and solution landscape research, track AI trends, and collaborate across teams to improve digital health solutions for patients and healthcare professionals.

AstraZeneca Cambridge, United Kingdom £28,000 pa

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12 Month University Industrial Placement Student (UIPS): Analytical Chemistry

This role involves supporting the development of pharmaceutical drugs through analytical chemistry techniques such as HPLC, GC, NMR, and mass spectrometry. You'll work within a dynamic team to ensure analytical data meets project timelines while adhering to GMP and GLP standards. The placement offers hands-on experience in a regulated lab environment and opportunities to present findings and develop scientific communication skills.

AstraZeneca Macclesfield, United Kingdom £28,000 pa

Innovation, Data & Analytics Team, Data Engineer

Build and operate the production data pipelines that power the Innovation, Data & Analytics team's AI-based workflows, implementing the canonical data model and ensuring reliable, timely, high-quality data for downstream analytics and agentic systems. Collaborate with data scientists, analysts, and governance teams to improve pipeline performance, ensure compliance, and support evolving analytical needs in a regulated healthcare environment.

Pfizer US$124,400 – US$207,400 pa

Innovation, Data & Analytics Team, Data Engineer

Build and operate production data pipelines that support AI-driven workflows, implementing canonical data models and ensuring high-quality, timely data delivery. Focus on healthcare data standards like OMOP/HEDIS, pipeline reliability, and collaboration with data scientists and analysts to support agentic systems and analytics. Work within regulated environments using Databricks, Snowflake, and cloud platforms while maintaining compliance and performance.

Pfizer US$124,400 – US$207,400 pa

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying pharmacokinetic/pharmacodynamic and exposure-response modelling to inform dose selection, trial design, and regulatory strategy. Work across development phases from early planning to lifecycle management, with a strong emphasis on hands-on quantitative analysis and scientific leadership within a cross-functional environment.

GSK Canterbury, United Kingdom US$183,150 – US$305,250 pa

Senior Director, R&D AI & Technology Portfolio

Lead strategic oversight and portfolio analytics for AI and technology investments across GSK's R&D value chain. Provide data-driven insights, support investment decisions, and coordinate the Technology Investment Board. Work cross-functionally to assess risks, dependencies, and strategic options including build, buy, partner, or acquire. Operate as a senior influencer without direct authority, shaping portfolio strategy in a hybrid work environment.

GSK

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology, modeling, and simulation efforts for infectious disease assets, driving dose selection and development strategy through population PK/PD and exposure-response modeling. Serve as a scientific leader within cross-functional teams while remaining hands-on with quantitative analyses. Contribute to regulatory submissions and advance model-informed drug development across the R&D lifecycle.

GSK United States £183,150 – £305,250 pa

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying quantitative methods to inform dose selection, trial design, and regulatory strategy. Work across development phases from early planning to lifecycle management, using population PK/PD and exposure-response modelling. Operate as a scientific leader within a cross-functional environment while remaining hands-on with data analysis and model development.

GSK

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology modeling and simulation efforts for infectious disease assets, combining hands-on pharmacometric analysis with strategic input across clinical development. Design and interpret studies, develop population PK/PD models, and guide dose selection and regulatory strategies. Work within cross-functional teams to influence development decisions and advance model-informed drug development.

GSK

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying pharmacokinetic/pharmacodynamic and population modelling to inform dose selection, trial design, and regulatory strategy. This senior individual contributor role combines hands-on quantitative analysis with strategic leadership across development phases, from early planning to lifecycle management. Work within a science-driven team to advance model-informed drug development using tools like NONMEM, R, and PBPK, while collaborating with cross-functional partners and supporting regulatory submissions.

GSK US$183,150 – US$305,250 pa

A

12 Month University Industrial Placement Student (UIPS): Synthetic - Organic Chemistry

This 12-month industrial placement offers hands-on experience in synthetic organic chemistry within AstraZeneca’s drug discovery and development teams. Placement students in Cambridge will work on novel multi-step syntheses with medicinal or peptide chemists, while those in Macclesfield will focus on scalable, sustainable process chemistry for kilogram-scale production. The role involves techniques in organic synthesis, purification, automation, and cross-team collaboration, with opportunities to present work and build transferable scientific skills.

AstraZeneca Cambridge, United Kingdom £28,000 pa

Innovation, Data & Analytics Team, AI/ML Engineer (Agentic Systems)

Design and build production-grade agentic systems that translate data science methodologies into reliable AI workflows. Focus on orchestration frameworks, prompt architecture, and API integrations while ensuring compliance, monitoring, and cost control in regulated environments. Collaborate across data science, engineering, and governance teams to harden systems for deployment in the life sciences sector.

Pfizer US$162,900 – US$271,500 pa