Biotechnology Jobs

• London
• Hybrid · 3 days in office
• Senior · manages people

Lead computational chemistry strategy across drug discovery programs, applying AI-first approaches to hit finding, molecular design and lead optimisation. Work with ML scientists to embed generative models into cheminformatics workflows, with some roles managing 2-3 computational chemists.

REINVENT · AlphaFold · Large Language Models

• London
• Hybrid · 3 days in office
• Lead · manages people

Lead a team of biologists in the Exploratory Sciences group, owning in vitro pharmacology strategy for novel modalities such as TPD, molecular glues and peptides. Design screening cascades and quantitative assays, manage CRO studies, and champion LLM agentic workflows and in silico hypothesis building alongside ML and engineering colleagues.

SPR · GCI · nanoDSF +5

• Manchester
• Mid-level

Monitors clinical trial sites through selection, initiation, monitoring and close-out visits in line with GCP and ICH guidelines, while driving subject recruitment and tracking regulatory submissions, CRF completion and data queries. Works within a full-service, multi-sponsor site management team, training site staff and maintaining Trial Master File documentation.

• Manchester
• Mid-level

Monitors oncology clinical trial sites through selection, initiation, monitoring and close-out visits, ensuring compliance with GCP and ICH guidelines. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains Trial Master File documentation. Works within IQVIA UK's multi-sponsor Site Management team, with travel to sites required.

Trial Master File · Investigator's Site File

• Wrexham
• Hybrid
• Lead
• Permanent

Leads Cell Line Development and Upstream Process Development strategies for biologic products, from candidate selection through commercial manufacturing. Acts as subject matter expert within cross-functional CMC teams, managing CDMO partnerships, supporting regulatory submissions and technology transfer, and mentoring junior scientists.

CHO

• London
• Hybrid
• Mid-level

Leads global cross-functional teams to plan, coordinate and deliver regulatory submissions for new marketing authorisations, new indications and other major filings. Manages integrated submission timelines, scenario planning, risk mitigation and forecasts, working with Regulatory Affairs, Clinical, Quality and Manufacturing under the CTD/eCTD framework.

RIMS

• Cambridge
• On-site
• Entry level
• Contract

Hands-on laboratory role supporting a state-of-the-art multiomics facility, running Illumina and Nanopore sequencing, bulk RNA/DNA library prep and single-cell workflows such as 10x Genomics and Parse Bio. The post also covers lab automation, instrument maintenance, SOPs, purchasing and advising researchers on experimental design within a collaborative core-facility team.

Illumina · Nanopore · 10x Genomics +3

• Oxford
• On-site
• £36,360 – £42,434 pa
• Entry level
• Contract

Supports an experimental programme building predictive models of cells, maintaining mammalian cell systems and running workflows such as endogenous protein tagging, CRISPR perturbation, optical pooled screening, live-cell imaging and proteomics. Works with computational and experimental researchers, generating engineered cell models and analysing data within a collaborative lab.

CRISPR · Flow Cytometry · Immunoblotting +4

• Sheffield
• £39,560 – £48,337 pa
• Entry level
• Contract

Lead the design, assembly and clinical validation of a novel dialyser prototype within the Thermofluids Group, testing with blood-mimicking fluids and human blood to assess cleaning efficiency, clotting risk and biocompatibility. Work alongside two other Research Associates covering numerical simulation and experimental fluid dynamics, in collaboration with the Medical School and Sheffield Teaching Hospitals.

• Sheffield
• £39,560 – £41,885 pa
• Entry level
• Contract

Contribute to a research programme analysing explanted polymeric medical devices, investigating how implant degradation, tissue responses and patient-specific factors drive complications. Establish experimental and sample-handling workflows, develop lab methods to characterise tissue and immune responses, and collaborate with academic, clinical, regulatory and patient partners including Sheffield Teaching Hospitals and Cambridge.

• London
• On-site
• Entry level
• Permanent

Contributes to the design and execution of cellular and biochemical assays, including arrayed CRISPR perturbation screens in established cell models, and maintains primary and immortalised mammalian cell lines with sample tracking and QC. Runs phenotypic readouts such as flow cytometry, RT-qPCR and ELISA, performs data analysis and quality assurance, and reports outcomes to cross-functional project teams. Based in London wet labs within a matrixed TechBio environment.

CRISPR · Flow Cytometry · RT-qPCR +3

• Lancaster
• £33,002 – £37,694 pa

Support a collaborative project developing materials for sustainable agriculture, using materials preparation, characterisation and in vitro biological testing to study how material properties affect plant interactions. The post also involves prototype validation, health and safety implementation and laboratory work within a rapidly expanding chemistry department.

• London
• On-site
• Mid-level

Develops and optimises therapeutic delivery formulations, designing lab experiments to assess stability, physicochemical properties and in vitro performance. Works in a multidisciplinary biotech team, characterising formulations analytically and supporting scale-up and tech transfer towards manufacturing. Distinct for its blend of formulation science, experimental development and translational research.

• Oxford
• On-site
• Entry level

Postdoctoral researchers join an interdisciplinary team fabricating three-dimensional living, synthetic and hybrid tissues for disease modelling, therapeutic testing and organ repair. Openings span cell biology, electrophysiology, bioinformatics, hydrogel science and tissue engineering, combining stem cell biology, bioprinting and device engineering within a group of about 15 members.

Multielectrode Arrays · Calcium Imaging · Optogenetics +4

• Cambridge
• On-site
• £38,448 – £46,970 pa
• Entry level
• Contract

Primarily experimental wet-lab postdoc developing programmable nucleic-acid systems that sense defined human genomic sequences and convert molecular recognition into engineered DNA outputs, with applications to genetic privacy. Based in the Department of Genetics, the role involves hands-on design, construction and troubleshooting of novel molecular systems plus quantitative analysis of assay performance to guide experimental iterations.