Latest Drug Discovery Jobs

ViiV Healthcare (GSK) Senior Director, Clinical Development

As a Senior Medical Director at ViiV Healthcare, you will lead the design and delivery of early development plans for HIV treatments, ensuring clinical excellence and medical governance across Phase 1-4 studies. You will collaborate with internal and external stakeholders to design, execute, and interpret clinical studies, focusing on long-acting medicines and ensuring patient safety and data integrity.

GSK United States

On-site Permanent

ViiV Healthcare (GSK) Senior Director, Clinical Development

This role involves leading the design and delivery of early development plans for HIV treatments, ensuring clinical excellence and medical governance across Phase 1-4 studies. You will collaborate with internal and external stakeholders to design, execute, and interpret clinical studies, ensuring patient safety and scientific excellence.

GSK

On-site Permanent

Executive Director Clinical Operations, Program Management

This role leads global clinical program delivery within AstraZeneca’s Oncology portfolio, focusing on strategic planning, operational excellence, and cross-functional leadership across late-stage development. The Executive Director will manage senior program directors, drive standardization, resolve escalated issues, and strengthen internal and external partnerships to accelerate patient impact. It involves governance, resource planning, financial stewardship, and leading organizational change in a dynamic, science-driven environment.

AstraZeneca Cambridge, United Kingdom

Hybrid Permanent

VP and Head of Operational Effectiveness

Lead the design and execution of operational effectiveness strategies across GSK’s R&D organisation, focusing on clinical trial delivery, process transformation, and performance analytics. Drive measurable improvements in speed, quality, and compliance by reimagining ways of working, building capabilities, and leveraging data-driven insights. Oversee key operational functions including third-party management, clinical documentation, and project management support to ensure high-quality, efficient outcomes aligned with global priorities.

GSK €190,500 – €317,500 pa

Hybrid Permanent

VP and Head of Operational Effectiveness

Leads operational effectiveness for clinical trial programs across GSK’s R&D organisation, driving process reimagination, performance intelligence, and transformation to accelerate drug development. Focuses on data-driven insights, operational excellence in key capabilities like third-party management and eTMF, and cultural change to improve speed, compliance, and quality. Works globally with senior leadership to deliver measurable improvements aligned with strategic goals.

GSK

Hybrid Permanent

VP and Head of Operational Effectiveness

This role leads operational effectiveness for GSK’s R&D organization, focusing on accelerating clinical trial delivery through data-driven performance frameworks, process redesign, and transformation programs. The VP will drive measurable improvements in speed, quality, and compliance across development operations, while building capabilities in areas like third-party management, eTMF, and project management. The position requires integrating advanced analytics, leading large-scale change, and fostering a culture of continuous improvement to support GSK’s global R&D ambitions.

GSK €190,500 – €317,500 pa

Hybrid Permanent

VP and Head of Operational Effectiveness

Leads operational effectiveness for clinical trial programs across GSK’s R&D organisation, driving process transformation, performance intelligence, and capability building to accelerate drug development. Focuses on data-driven insights, operational excellence in areas like third-party management and eTMF, and large-scale change initiatives to improve speed and quality. Works at a global senior leadership level to embed a culture of continuous improvement and innovation.

GSK €190,500 – €317,500 pa

Hybrid Permanent

VP and Head of Operational Effectiveness

Leads operational effectiveness for clinical trial delivery across GSK’s R&D organisation, driving process reimagination, performance intelligence, and transformation programs to accelerate development timelines. Focuses on data-driven insights, operational excellence in key capabilities like third-party management and documentation, and culture change to enable best-in-class performance. Works across global teams to embed continuous improvement and technology adoption at scale.

GSK €190,500 – €317,500 pa

Hybrid Permanent

SERM Scientific Director

The SERM Scientific Director will lead the safety evaluation and risk management of GSK's key assets, ensuring scientifically sound review and interpretation of data. They will develop and execute safety strategies, manage safety governance, and represent GSK on cross-functional teams to address product safety issues and improve regulatory adherence.

GSK

On-site Permanent

Senior Manager - CMC Regulatory Affairs Biopharm Development Projects

This role involves leading CMC regulatory activities for GSK's investigational, late development, and early commercial products. Responsibilities include driving CMC strategy, preparing regulatory documents, managing project activities, mentoring staff, and engaging with external agencies to ensure compliance and expedite submissions.

GSK Canterbury, United Kingdom

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for high-impact, complex global trials in hepatology, renal, and cardiovascular disease, with a focus on late-phase outcomes studies and rare diseases. The position shapes operational strategy, drives innovation in trial design, and ensures delivery across a diverse asset portfolio. It involves leading vendor partnerships, managing regulatory and quality compliance, and developing clinical teams within a patient-ambitious, data-driven environment.

GSK Stevenage, United Kingdom US$242,550 – US$404,250 pa

Hybrid Permanent

Senior Manager - CMC Regulatory Affairs Biopharm Development Projects

This role involves leading CMC regulatory activities for GSK's investigational, late development, and early commercial products. Responsibilities include driving CMC strategy, preparing regulatory documents, managing project activities, and mentoring staff. The position requires a strong understanding of regulatory requirements and the ability to communicate complex issues across departments and with external agencies.

GSK

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for complex, multi-indication assets in hepatology, renal, and cardiovascular disease, with strategic oversight of global Phase III trials, rare disease programmes, and co-development partnerships. The position involves shaping operational strategy, managing high-level vendor relationships, and driving innovation in trial design including decentralised and hybrid models. It requires leadership in risk management, data-driven decision-making, and team development within a global regulatory and compliance framework.

GSK United Kingdom US$242,550 – US$404,250 pa

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for high-complexity assets in hepatology, renal, and cardiovascular disease, with a focus on global Phase III outcomes trials, rare disease programmes, and co-development partnerships. The position drives end-to-end operational strategy, including country and site selection, patient recruitment, risk management, and vendor oversight, while ensuring alignment with clinical development and evidence generation plans. It also involves direct leadership of clinical teams, fostering innovation in trial design, and maintaining inspection readiness across the portfolio.

GSK US$242,550 – US$404,250 pa

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for high-impact, complex global trials in hepatology, renal, and cardiovascular disease, with a focus on late-phase outcomes studies and rare diseases. The position involves shaping operational strategy, managing CRO partnerships, and driving innovation in trial design while ensuring quality and compliance. Leadership includes direct management of clinical teams and strategic input into asset development across the R&D pipeline.

GSK US$242,550 – US$404,250 pa

On-site Permanent