Latest regulatory affairs Jobs

Medical Director, Oncology Clinical Development

The Medical Director, Oncology Clinical Development, will lead clinical research activities for GSK’s oncology portfolio, collaborating with internal and external stakeholders to design and execute phase 1-3 clinical trials. Key responsibilities include protocol development, medical monitoring, safety data review, and strategic partnerships with key experts in the field.

GSK

Hybrid Permanent

Medical Director, Oncology Clinical Development

The Medical Director, Oncology Clinical Development, will lead clinical research activities for GSK’s oncology antibody drug conjugate (ADC) portfolio, focusing on advancing the development of clinical trials from early to late stages. Key responsibilities include protocol development, medical monitoring, safety data review, and collaboration with a multi-disciplinary team of experts to ensure the scientific integrity and timely delivery of clinical trials.

GSK

Hybrid Permanent

Clinical Development Director - Renal

The Clinical Development Director is responsible for leading and supporting the delivery of clinical deliverables for a section of a global clinical program or a large, complex trial. This role involves collaborating with various teams to ensure data quality, regulatory compliance, and scientific accuracy in clinical trials and publications.

Novartis London, United Kingdom

Hybrid Permanent

Senior Clinical Development Medical Director - Renal

The Senior Clinical Development Medical Director will lead the strategy and execution of renal clinical development programs, from early to late phases. Responsibilities include providing clinical leadership, developing regulatory documents, ensuring patient safety, and collaborating with global teams and stakeholders.

Novartis London, United Kingdom

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

The Global Development Lead (GDL) is responsible for leading the clinical development of assigned assets in Internal Medicine. This involves designing and executing clinical trials, creating development plans, and ensuring regulatory compliance. The role also includes collaborating with cross-functional teams, providing expert input on clinical data, and engaging with external stakeholders to drive strategic insights.

Pfizer

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

The Global Development Lead (GDL) is responsible for leading the clinical development of assigned assets in Internal Medicine. This involves designing and executing clinical trials, creating development plans, and collaborating with cross-functional teams to ensure regulatory submissions and product approvals globally. The role also includes providing expert input on trial design, regulatory activities, and engaging with external stakeholders to drive strategic insights.

Pfizer

On-site Permanent

Process Engineer - Drug Substance Manufacture (DSM)

This role involves optimizing chemical manufacturing processes for drug substances in a regulated pharmaceutical environment. The engineer will lead process improvements, scale-up projects, and technology transfers while ensuring compliance with safety, quality, and environmental standards. Work includes root-cause analysis, change control management, and cross-functional collaboration to enhance capacity, robustness, and efficiency in API production.

AstraZeneca Macclesfield, United Kingdom

Hybrid Permanent

Executive Director, Strategy, Oncology R&D

This role involves crafting and driving the global Oncology R&D strategy, integrating clinical, scientific, and commercial insights to shape portfolio priorities. You will advise senior leadership, optimize investment decisions, and collaborate across functions to deliver high-impact strategic outcomes.

AstraZeneca United States US$270,222 – US$405,332 pa

On-site Permanent

Principal Research Associate, Clinical Biomarker Laboratory, Flow Cytometry

This role involves generating and analyzing high-parameter flow cytometry data from clinical trial samples to support immunology research in a GCLP-compliant environment. The scientist will operate advanced spectral flow platforms like the Cytek Aurora, perform ex vivo immune functional assays, and ensure data integrity through rigorous documentation and compliance. Emphasis is placed on innovation through AI-enabled tools, assay development, and mentoring within a collaborative, regulated laboratory setting.

Moderna

Hybrid Permanent

Senior Research Associate, Bioanalytical & Molecular Assays

This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and gel electrophoresis—to support clinical-stage mRNA programs. The scientist will generate high-quality RNA quantitation data in compliance with GCLP standards, collaborate across clinical and laboratory teams, and contribute to regulatory documentation and sample management strategies. The position emphasizes innovation through digital tools and automation within a fast-paced, compliance-driven environment.

Moderna

Hybrid Permanent

AI Strategy Director, Development Operations

The AI Strategy Director role involves driving the AI-native Development Operations strategy at GSK, focusing on identifying and deploying AI solutions that accelerate clinical trials and improve patient outcomes. Responsibilities include prioritizing AI opportunities, evaluating external capabilities, and leading cross-functional teams to prototype and deploy AI-enabled workflows.

GSK Stevenage, United Kingdom

On-site Permanent

CMC Leader (Director)

Leads end-to-end CMC strategy and execution for a pharmaceutical product from early development through commercialisation, including process development, regulatory filings, and lifecycle planning. Coordinates cross-functional global teams across R&D, supply chain, and regulatory to deliver clinical and commercial supply, ensuring technical transfer, quality compliance, and launch readiness. Focuses on complex modalities such as small molecules and oligonucleotides, with strong emphasis on regulatory strategy, risk management, and transition to commercial operations.

GSK Stevenage, United Kingdom

Hybrid Permanent

CMC Leader (Director)

Leads the development, industrialization, and lifecycle delivery of a physical medicine from early development through commercialization, ensuring seamless transition across stages. Coordinates cross-functional CMC and supply chain teams to deliver regulatory filings, process validation, and launch readiness, with a focus on complex products including small molecules and oligonucleotides. Drives strategic decision-making across R&D, manufacturing, and commercial functions to ensure timely, compliant, and scalable product supply.

GSK East Hertfordshire, United Kingdom

Hybrid Permanent

Director, DP Workstream Leader – Small Molecule Parenteral (LAIs and Oligos)

Leads drug product development for sterile long-acting injectables and oligonucleotides, guiding cross-functional teams in formulation, process development, and technology transfer. Ensures robust CMC strategies, regulatory compliance, and supply readiness across clinical to commercial phases. Focuses on delivering high-quality, patient-centric medicines through scientific leadership and matrix collaboration.

GSK East Hertfordshire, United Kingdom

Hybrid Permanent

Director, DP Workstream Leader – Small Molecule Parenteral (LAIs and Oligos)

Leads late-stage drug product development for sterile long-acting injectables and oligonucleotides, guiding cross-functional teams in formulation, process development, and technology transfer. Translates CMC and regulatory strategies into actionable plans, ensuring robust control strategies and compliance across clinical and commercial phases. Works within a matrix environment to align R&D, manufacturing, and supply chain functions for successful asset delivery.

GSK Stevenage, United Kingdom

Hybrid Permanent