Biotechnology Jobs

494 jobs for “Clinical Data Manager - Early Phase”

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GSK logo

GSK · 10000+ people · Public

Medical Director, Oncology Clinical Development - Hematology

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  • Baar Onyx
  • Hybrid · 2 days in office
  • US$222,750 – US$371,250 pa
  • Director

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for hematology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with hybrid working at least two days on-site.

AI

Last month
GSK logo

GSK · 10000+ people · Public

VP, Medicine Development Leader- Cancer Vaccines, Oncology Research Unit

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  • London
  • Hybrid · 2 days in office
  • US$340,500 – US$567,500 pa
  • Senior · manages people

Leads global development of a cancer vaccine asset from late-stage transition through approval and launch, acting as single point of accountability and chairing a cross-functional matrix Medicine Development Team spanning clinical, translational, regulatory, manufacturing and commercial. Drives strategy, go/no-go decisions and lifecycle plans for novel vaccine platforms such as mRNA and neoantigen-based therapies.

mRNA · Checkpoint Inhibitors

2 weeks ago

IQVIA

Sr. CRA 1 - Site Management

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  • Manchester
  • Senior

Monitors clinical trial sites across selection, initiation, monitoring and close-out visits in line with GCP, while driving subject recruitment and tracking regulatory submissions, CRF completion and data query resolution. Also trains site staff, maintains TMF/ISF documentation and may support site financial management and start-up activities.

Microsoft Word · Microsoft Excel · Microsoft PowerPoint

6 days ago

IQVIA

CRA II, Oncology

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  • Manchester
  • Mid-level

Monitors oncology clinical trial sites through selection, initiation, monitoring and close-out visits, ensuring compliance with GCP and ICH guidelines. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains Trial Master File documentation. Works within IQVIA UK's multi-sponsor Site Management team, with travel to sites required.

Trial Master File · Investigator's Site File

8 months ago

Moderna · 1001–5000 people · Late stage

Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based

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  • Oxford
  • On-site
  • Senior · manages people

Lead development, qualification, validation and execution of complex cell-based immunoassays generating clinical trial data across therapeutic areas. Act as scientific point of contact within the Immuno-assays group, performing GCP/GLP-compliant sample testing, authoring validation reports, and mentoring junior lab staff. Fully onsite at Harwell, reporting to the Associate Director, Immuno-assay UK.

GraphPad Prism · Microsoft Word · Microsoft Excel +2

Last month
CSL logo

CSL · 10001+ people · Public

Associate Director, Biostatistics

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  • Opfikon, Switzerland
  • Hybrid · 3 days in office
  • US$212,000 – US$251,000 pa
  • Director

Leads the full statistical contribution to a clinical development programme, defining statistical strategy for trial design, analysis and regulatory submissions, and representing Biostatistics in interactions with the FDA, EMA and PMDA. Also manages outsourcing to CROs and internal statistical programmers, and supports departmental improvement initiatives.

SAS · R

Last week
Novartis logo

Novartis

Director, Translational Medicine Expert (Neurodegeneration)

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  • London
  • Hybrid
  • Director

Leads end-to-end translational strategy for neurodegenerative and neuromuscular programs, bridging preclinical research to Phase 1–2 clinical development. Accountable for biomarker strategy, clinical endpoint selection and early-phase trial design, and serves as the Translational Medicine representative within global cross-functional project and clinical trial teams.

3 weeks ago

Moderna · 1001–5000 people · Late stage

Principal Scientist, Immunogenicity and Ligand Binding Assays

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  • Oxford
  • Hybrid · 3–4 days in office
  • Lead
  • Permanent

Provides scientific and hands-on leadership for immunogenicity and ligand binding assay bioanalysis supporting mRNA-LNP therapeutic programs, spanning assay development, validation, clinical sample testing and regulatory submissions. Ensures GcLP compliance and partners with cross-functional teams, with opportunities to work alongside data and AI-enabled analytical approaches.

ECL · Gyrolabs · Reporter Gene Assays +3

Visa sponsorship 5 months ago

Fortrea

CRA II (fixed-term)

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  • Maidenhead
  • Hybrid
  • Mid-level
  • Temporary

Monitoring investigator sites across the North of England for a routine post-market surveillance study within a dedicated FSP model. Involves on-site and remote monitoring, building relationships with investigators, and ensuring patient safety, data quality and regulatory compliance, with travel to Oxford at least monthly plus on-site onboarding and training.

Last month

Thermo Fisher Scientific

Scientist – Extended Characterization Europe - Client-dedicated - FSP

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  • Stevenage
  • On-site
  • Mid-level

Performs complex sample preparation and quantitative analysis of small molecules and biotherapeutics using instrumentation such as GC-MS, ICP-OES, HPLC and LC-MS, supporting both GMP and non-GMP stability studies. Works largely independently to set up, maintain and troubleshoot analytical instrumentation, interpret data for technical validity and compliance, and report results to client teams. Based full-time onsite at a pharmaceutical client site as part of a functional service provider partnership.

GC-MS · ICP-OES · HPLC +2

Last month
CSL logo

CSL · 10001+ people · Public

Senior Pharmacovigilance Scientist (Vaccines/ Products of National Significance)

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  • Opfikon, Switzerland
  • Senior

Leads safety review and end-to-end signal detection across a product's lifecycle, using quantitative and qualitative methods alongside Global Safety Leads. Contributes to aggregate safety reports, risk management plans and regulatory responses, and mentors junior PVS staff. Works cross-functionally with Development, Medical Affairs and Regulatory teams on vaccine and national-significance products.

Microsoft Excel

Last week
Novartis logo

Novartis

Senior Principal Biostatistician

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  • London
  • On-site
  • £57,190 – £106,210 pa
  • Lead

Lead all statistical work on assigned neuroscience clinical trials, from protocol development and statistical analysis plans to reporting and exploratory analyses. Drive implementation of innovative trial designs and modern statistical methodologies, collaborating with clinical, regulatory, data management and programming teams to support quantitative decision making.

Last month

Helical

Junior Business Development Associate

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  • London
  • Hybrid
  • Junior
  • Permanent

Hands-on business development role researching pharma and biotech accounts, writing outreach, and owning CRM pipeline hygiene in HubSpot. Works directly with founders and the head of sales, building sales materials and AI workflows while coordinating with the science team ahead of customer meetings.

HubSpot · LinkedIn

Last week

University of Exeter

PhD Studentship: From Variants to Placental Function: Using Cell-free DNA to Dissect the Functional Genomics of Adverse Pregnancy Outcomes

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  • Exeter
  • Entry level
  • Contract

Computational PhD project using cell-free DNA sequencing to infer placental gene activity and dissect how genetic variants linked to adverse pregnancy outcomes affect placental function. The student develops tools to map nucleosomal footprints, integrates them with single-cell RNA-seq markers and GWAS summary statistics, and may generate new plasma data.

scRNA-seq · cfDNA Sequencing · GWAS

Last week

Parexel

Medical Director/Study Physician - CD Inflammation - Sponsor Dedicated

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  • London
  • Remote
  • Director

Medically responsible at trial level across preparation, conduct and reporting phases, providing medical expertise and oversight from Trial Design Outline to Clinical Trial Report. Dedicated to a single sponsor in the EMEA region, the role involves authoring high-quality clinical trial protocols, co-authoring Clinical Quality Monitoring plans, integrating medically relevant data into risk-based quality management, and performing ongoing reviews of medical data.

4 months ago

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