Latest Drug Discovery Jobs

Associate Director, Clinical Program Management, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, coordinating cross-functional global teams and managing timelines, budgets, and vendor partnerships. The role leverages AI and emerging technologies to drive efficient clinical development with a focus on high-probability outcomes. It involves strategic oversight of CROs and collaborators while ensuring alignment between clinical objectives and company goals.

Isomorphic Labs England

Hybrid Permanent

General Application - Register Your Interest

This is a general interest application for roles at Isomorphic Labs, an AI-driven drug discovery company. Candidates may be considered for positions including Software Engineers, ML Researchers, Computational Chemists, and Technical Project Managers. The role involves interdisciplinary collaboration to advance AI models for rational drug design and digital biology, within a culture emphasising curiosity, bravery, determination, and teamwork.

Isomorphic Labs United Kingdom

Hybrid Permanent

Medical Director Clinical Development- Respiratory

Lead clinical development for respiratory assets within GSK’s Respiratory, Immunology & Inflammation Research Unit, driving translational and clinical strategies from early to late stages. Provide medical oversight, design studies, and collaborate across functions to deliver innovative medicines addressing unmet patient needs in respiratory disease.

GSK Stevenage, United Kingdom

Clinical Development Medical Director - Cardiovascular

Lead clinical development for cardiovascular programs within GSK’s Respiratory, Immunology & Inflammation Research Unit, driving translational and clinical strategies from early to late stages. Provide medical oversight, design clinical development plans, and collaborate across functions to deliver innovative medicines addressing unmet patient needs. Work in a hybrid model with a future relocation from Stevenage to Cambridge by 2029.

GSK Stevenage, United Kingdom

Hybrid Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

Leads clinical development for Internal Medicine assets within Pfizer's R&D organization, with end-to-end accountability for creating and executing global clinical development plans. Serves as the primary clinical point of contact across cross-functional teams and external partners, driving trial design, regulatory submissions, and lifecycle strategy. Focuses on obesity and related therapeutic areas, integrating innovation, patient engagement, and regulatory expertise to advance drug development.

Pfizer £214,900 – £358,100 pa

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

Leads clinical development for assigned internal medicine assets within Pfizer's Research & Development division, with end-to-end accountability for creating and executing global clinical development plans. Oversees cross-functional teams to design and deliver clinical trials supporting regulatory submissions, while providing therapeutic expertise in obesity and endocrinology. Engages external stakeholders and contributes to regulatory strategy, safety reporting, and product labeling.

Pfizer £214,900 – £358,100 pa

On-site Permanent

(Fixed Term) Laboratory Technician, Clinical Biomarker Laboratory, Immunoassay

This role involves hands-on laboratory work supporting immunoassay development and clinical testing for Moderna’s mRNA-based therapeutic programs. The technician will prepare reagents, conduct sample analysis, ensure regulatory compliance, and contribute to high-quality data generation for clinical trials. Based in Oxford, the position requires full-time on-site work in a regulated lab environment with occasional overtime.

Moderna Oxford, United Kingdom

On-site Contract

Associate Director, Global Regulatory Science, CMC

Leads global regulatory strategy for CMC (Chemistry, Manufacturing, and Controls) in support of mRNA-based medicines, ensuring compliance with international regulations and guiding submissions across multiple therapeutic areas. Works closely with manufacturing, quality, and development teams to prepare high-quality regulatory documentation and engage with health authorities. Focuses on biologics, particularly in vaccines, oncology, and rare diseases, within a rapidly expanding biotech environment.

Moderna London, United Kingdom

Hybrid Permanent

Global Medical Affairs Director, Immunology

Lead the development and execution of global medical strategies for immunology products across their lifecycle, from development to market. Drive evidence generation through real-world studies, registries, and investigator-initiated trials while engaging key scientific experts and patient groups. Provide medical leadership at major congresses and advisory boards, ensuring compliance and strategic input into regulatory, access, and launch planning.

Novartis London, United Kingdom £93,870 – £174,330 pa

Global Medical Affairs Director, Immunology, Rap-cel (CAR-T)

Leads global medical strategy for a novel CAR-T therapy in autoimmune diseases, driving evidence generation and scientific engagement with key opinion leaders, patient groups, and research institutions. Oversees real-world evidence, registries, and investigator-initiated studies while ensuring compliance and medical governance. Collaborates cross-functionally to shape clinical development, regulatory, and launch strategies in a rapidly evolving immunology landscape.

Novartis London, United Kingdom £93,870 – £174,330 pa

Hybrid Permanent

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

Develops and validates ligand-binding and cell-based assays to support clinical programs for mRNA medicines. Performs pharmacodynamic and immunogenicity testing in compliance with GcLP, using platforms like Thermo Watson LIMS. Contributes to assay development, reagent management, and regulatory documentation in a fast-paced, innovative lab environment.

Moderna

Hybrid Permanent

Sr. Manager, Site Budgets and Contracts

This role involves leading the creation and management of investigator site budgets and contracts for global clinical trials, using Grants Manager and FMV benchmarking tools. The Senior Manager collaborates with CROs, Legal, and Clinical Operations to ensure site budgets align with study forecasts and are executed on time. Responsibilities include strategic planning, contract negotiation oversight, risk identification, and process improvement within an outsourced trial model.

Moderna

Hybrid Permanent

Associate Director, Resilience Strategic Partnerships – UK

Lead the execution of Moderna’s landmark Long-Term Strategic Partnership with the UK Government, coordinating cross-functional teams across R&D, manufacturing, and access to deliver on public health commitments. Serve as the primary liaison with senior government stakeholders including UKHSA and DHSC, ensuring alignment, governance, and delivery against strategic objectives. Drive program management, risk mitigation, and stakeholder engagement in a high-visibility role shaping the future of mRNA vaccine development and biomanufacturing in the UK.

Moderna London, United Kingdom

On-site Permanent

Associate Director, Resilience Strategic Partnerships – UK

Lead the execution of Moderna’s Long-Term Strategic Partnership with the UK Government, coordinating cross-functional teams across R&D, manufacturing, and access to deliver mRNA-based vaccines. Serve as the primary liaison with senior government stakeholders including UKHSA and DHSC, ensuring delivery of public health commitments through strategic planning, governance, and risk management. Drive program alignment and accountability across complex, interdependent workstreams in a fast-paced, high-impact environment.

Moderna Tameside, SK15 3JG, United Kingdom

On-site Permanent

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s new biotech site in Harwell, Oxford. The Facilities Engineering Manager will oversee maintenance, vendor performance, and engineering projects across R&D and manufacturing environments, ensuring compliance and operational reliability. The position emphasizes continuous improvement, digital tool integration, and collaboration with global teams in a GMP-regulated setting.

Moderna Oxford, United Kingdom

On-site Permanent