Lead clinical development for cardiovascular assets within GSK's Respiratory, Immunology & Inflammation Research Unit, driving translational and clinical strategies from early to late stages. Provide medical oversight, design studies, and collaborate across functions to deliver innovative medicines addressing unmet patient needs. Work in a hybrid model with a future relocation to Cambridge.
Lead clinical development for cardiovascular assets within GSK's Respiratory, Immunology & Inflammation Research Unit, driving translational and clinical strategies from early to late stages. Oversee study design, regulatory interactions, and cross-functional collaboration to deliver innovative medicines addressing unmet patient needs. Work in a hybrid model with significant scientific and strategic leadership responsibilities.
Develops and validates ligand-binding and cell-based assays to support clinical programs for mRNA medicines. Performs pharmacodynamic and immunogenicity testing in compliance with GcLP, using platforms like Thermo Watson LIMS. Contributes to assay development, reagent management, and regulatory documentation in a fast-paced, innovative lab environment.
This role involves providing clinical leadership and strategic medical input for cardiovascular/stroke drug development programs, including designing and executing global clinical trials. The Senior Clinical Development Medical Director will act as the global medical lead, interpreting clinical and safety data, contributing to regulatory submissions, and collaborating with cross-functional teams and external stakeholders. The position plays a key role in shaping clinical strategy and ensuring patient safety across the development lifecycle.
The Clinical Development Director leads and supports clinical development activities within a global program, focusing on strategy, trial execution, data analysis, and regulatory documentation. This role involves close collaboration with cross-functional teams, ensuring scientific rigor and data quality across phases I–IV trials, particularly in late-phase development. The position requires strong scientific expertise, leadership in clinical operations, and active participation in safety and regulatory initiatives.
This role involves leading clinical development for internal medicine assets within Pfizer's Research & Development division, with a focus on obesity-related therapeutics. The Global Development Lead serves as the primary clinical accountability point, designing and executing global clinical development plans, regulatory submissions, and cross-functional team leadership. The position requires deep expertise in endocrinology or chronic weight management and extensive experience in Phase 1-3 clinical trials, translational medicine, and regulatory strategy across global markets.
This role leads clinical development for assigned assets in Internal Medicine within Pfizer's R&D division, with accountability for designing and executing global clinical development plans. The individual will guide cross-functional teams through trial design, regulatory submissions, and lifecycle management, while serving as a therapeutic expert and strategic partner across internal and external stakeholders. Emphasis is placed on innovation, patient engagement, and compliance with global regulatory standards.
Operate and maintain mRNA vaccine production equipment in compliance with cGMP and safety standards, executing manufacturing processes, troubleshooting equipment and digital systems, and supporting quality documentation and continuous improvement initiatives. Work within a cross-functional team to ensure timely batch release and operational excellence in a fast-paced, highly regulated environment.
Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.
This role involves designing and implementing quality test procedures for both software and hardware in medical device products. Responsibilities include attending design meetings, writing test plans, and ensuring compliance with regulatory standards.
Lead a team of software and firmware engineers developing medical technology and connected devices in a regulated environment. Drive technical excellence across the full software development lifecycle, from architecture to validation, while fostering a culture of innovation and collaboration. Work closely with cross-functional teams to deliver integrated, safety-critical solutions.
Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.
Leads the end-to-end design, build, and commissioning of a clinical-stage GMP gene therapy manufacturing suite, ensuring compliance with EU GMP Annex 1 and other regulatory standards. Provides strategic oversight of facilities engineering, maintenance, and contamination control, while managing cross-functional teams and vendor relationships. Ensures operational readiness, regulatory compliance, and continuous improvement across both manufacturing and corporate facilities.
This role involves preparing and sterilising culture media and laboratory solutions, cleaning and maintaining glassware, and operating autoclaves and related equipment to support plant biology research. The technician ensures compliance with safety and regulatory standards while maintaining accurate records and managing consumable stock levels. Their work enables smooth laboratory operations and high-quality scientific outcomes in a cutting-edge research environment.
This role involves deploying and integrating generative AI models into pharmaceutical and biotech customers' scientific workflows. The engineer will lead end-to-end technical deployments, build production-grade API integrations and data pipelines, and act as a technical liaison between customers and internal research teams. A strong background in ML infrastructure, cloud platforms, and customer-facing delivery in life sciences is essential.
