Jobs in Exeter

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

This role leads clinical development for assigned assets in Internal Medicine within Pfizer's R&D division, serving as the primary clinical accountability point on the Global Medicine Team. The leader designs and executes global clinical development plans, guides cross-functional teams through trial phases, and supports regulatory submissions and lifecycle strategies. Emphasis is placed on innovation, patient engagement, and strategic external collaboration to advance obesity and internal medicine therapeutics.

Pfizer

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (MD)

This role involves leading clinical development for Internal Medicine assets within Pfizer's Research & Development division, with end-to-end accountability for creating and executing global clinical development plans. The position requires deep therapeutic expertise in chronic weight management or endocrinology, leadership of cross-functional teams, and active engagement in trial design, regulatory submissions, and lifecycle strategy. The role operates in a hybrid work model and may include responsibilities across the Obesity portfolio.

Pfizer United States £274,500 – £457,500 pa

On-site Permanent

Senior Director, Portfolio Integration Lead - Hematology

Leads cross-programme scientific strategy and integration across GSK’s oncology portfolio, with a focus on hematology. Provides expert guidance on disease biology, biomarker strategies, and clinical development innovation across multiple assets. Champions data-driven decision-making, trial innovation, and external engagement to align portfolio direction and accelerate development.

GSK Stevenage, United Kingdom US$242,250 – US$403,750 pa

Hybrid Permanent

Director of Clinical Pharmacology Modeling and Simulation

Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying pharmacokinetic and pharmacodynamic principles to support drug development from early stages through registration and lifecycle management. Develop population PK/PD and exposure-response models, guide dose selection, and present evidence to regulatory bodies. Work within cross-functional teams while maintaining hands-on involvement in quantitative analysis and strategic decision-making.

GSK Stevenage, United Kingdom £183,150 – £305,250 pa

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s new biotech site in Harwell, Oxford. The Facilities Engineering Manager will oversee maintenance, vendor performance, and engineering projects across R&D and manufacturing environments, ensuring compliance and operational reliability. The position emphasizes continuous improvement, digital tool integration, and collaboration with global teams in a GMP-regulated setting.

Moderna Oxford, United Kingdom

On-site Permanent

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s biotech manufacturing site in Harwell. The Facilities Engineering Manager ensures operational reliability, oversees vendor performance, and drives maintenance excellence across R&D and manufacturing environments. The position emphasizes continuous improvement, compliance, and the use of digital tools including AI-enabled systems, within a GMP-regulated setting.

Moderna

On-site Permanent

Vendor Program Strategy Director - Global Clinical Operations

This role involves developing and executing vendor strategies for clinical programs, aligning vendor needs with program objectives, and driving operational efficiency and value realization. The Director will work closely with clinical teams, procurement, and other stakeholders to ensure effective vendor management and strategic decision-making.

Novartis London, United Kingdom

Postdoctoral Research Scientist in Immunology

This role involves designing, producing, and characterising novel engineered proteins to modulate cell-surface receptor signalling in myeloproliferative neoplasms. Responsibilities include developing protein expression and purification methods, establishing functional assays, and collaborating with internal and external partners.

University of Oxford Oxford, South East England, United Kingdom £39 – £40 pa

Contract

Senior Systems Engineer

This role involves leading the design, testing, and verification of electromechanical systems in medical devices, with a focus on improving reliability and supporting technology transfer to production. The engineer will conduct root cause analyses, optimize system performance, and lead cross-functional design reviews. Work spans system integration, validation, and documentation within a regulated healthcare technology environment.

GxPeople Global Trowbridge, Wiltshire, BA14 8EY, United Kingdom £65,000 – £75,000 pa

Electromechanical Engineer

Design and test electromechanical components for an FDA-regulated, point-of-care diagnostic device, including sensors, actuators, and integrated systems. Collaborate with software and systems engineers to develop a reliable, secure medical instrument, while improving test processes and evaluating emerging technologies. Work within a cross-functional team to drive innovation in a regulated environment with real-world clinical impact.

GxPeople Global Bath, Somerset, United Kingdom £60,000 – £70,000 pa

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Director, Biostatistics

Leads the Biostatistics function, building and managing a team of statisticians and programmers while providing strategic statistical input across clinical development programs. Plays a central role in study design, regulatory engagement, and innovation in methodologies tailored to gene therapy and rare diseases. Works closely with cross-functional teams and global regulatory agencies to ensure robust, compliant, and efficient development of gene therapies.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Associate Director / Director – Integrated Drug Discovery & Project Leadership

Lead multidisciplinary drug discovery projects from target validation through hit identification and lead optimisation, integrating biology, chemistry, DMPK, and translational sciences. Provide scientific and people leadership within a GPCR-focused discovery engine powered by structural biology and computational design. Drive innovation, portfolio progression, and team development in a fast-paced biopharma environment.

Talentmark Great Abington, Cambridgeshire, United Kingdom

Director, Clinical Pharmacology

Lead clinical pharmacology and pharmacometrics strategy for rare disease and oncology programs, designing studies and guiding regulatory submissions. Oversee modeling and simulation to inform dose selection and accelerate drug development. Collaborate across translational, clinical, and preclinical teams in a tech-driven biopharma environment.

Recursion United Kingdom US$212,900 – US$297,000 pa

Hybrid Permanent

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Executive Director / Vice President, Business Development

Lead business development strategy to identify and execute strategic partnerships, in- and out-licensing deals, co-developments, and M&A opportunities in oncology and autoimmune disease. Represent Autolus at high-level meetings, build relationships across biotech, pharma, and academia, and collaborate with cross-functional teams to align BD initiatives with corporate goals. Requires deep expertise in biopharma deal-making and strong scientific-business acumen.

Autolus