Latest Drug Discovery Jobs

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Medical Director, Oncology Clinical Development - GU

This role involves leading medical oversight and clinical strategy for genitourinary (GU) oncology trials within GSK’s R&D pipeline. The Medical Director provides physician-level expertise in study design, safety monitoring, data interpretation, and regulatory engagement, ensuring patient safety and scientific integrity. They collaborate with cross-functional teams and external experts to advance innovative cancer treatments through clinical development.

GSK £189,750 – £316,250 pa

Medical Director, Oncology Clinical Development - GU

This role involves leading medical strategy and oversight for genitourinary (GU) oncology clinical trials within GSK’s R&D pipeline. The Medical Director provides physician-level expertise in study design, real-time safety monitoring, data interpretation, and regulatory engagement, ensuring patient safety and clinical integrity. They work cross-functionally within a matrix team to advance innovative cancer therapies from development through to regulatory submission and scientific dissemination.

GSK £189,750 – £316,250 pa

Director, Translational Medicine Expert (Neurodegeneration)

This role involves leading the translational strategy for neurodegenerative programs, from preclinical research to early clinical development. Responsibilities include biomarker strategy, clinical trial design, and cross-functional leadership, with a focus on integrating patient-centered approaches and advancing scientific collaborations.

Novartis London, United Kingdom

(Fixed-Term) GMP Engineering Specialist

This role involves hands-on engineering support for GMP manufacturing equipment, ensuring operability and reliability across process platforms. Responsibilities include troubleshooting, project management, and continuous improvement, with a focus on mRNA manufacturing at Moderna's Harwell and Norwood facilities.

Moderna Oxford, United Kingdom

Senior GMP Maintenance Technician

This role involves hands-on maintenance and troubleshooting of GMP and non-GMP equipment in a new manufacturing facility. Responsibilities include equipment reliability, CMMS ownership, and collaboration with Engineering and QA on capital and reliability initiatives.

Moderna Oxford, United Kingdom

Global Regulatory Associate Director, Life Cycle Management

This role involves managing regulatory maintenance activities for a high-complexity pharmaceutical product portfolio, ensuring compliance and timely submissions to global health authorities. The individual will lead strategic regulatory input across cross-functional teams, respond to complex queries, and support continuous process improvements. It is a hybrid or remote position with a focus on lifecycle management of innovative medicines.

Novartis £67,900 – £126,100 pa

Hybrid Permanent

Senior Medical Director, Oncology Clinical Development - Sarcoma

This role involves leading clinical development for sarcoma within GSK's oncology portfolio, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety monitoring, contribute to regulatory interactions, and represent the programme externally at scientific forums. Based on-site in Waltham, MA, the position requires integration with cross-functional teams and mentorship of clinical staff to ensure patient-centred, scientifically rigorous drug development.

GSK £284,250 – £473,750 pa

Senior Medical Director, Oncology Clinical Development - Sarcoma

This role involves leading clinical development strategy for sarcoma within GSK's oncology portfolio, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety evaluation, mentor clinical teams, and represent the programme in regulatory and scientific forums. Based on-site at a GSK location with future relocation to Cambridge, UK.

GSK £284,250 – £473,750 pa

Head, Oncology Clinical Development - ADCs

Lead the clinical development strategy for antibody-drug conjugates (ADCs) across multiple tumor types, from early-phase through registrational trials and market launch. Drive integrated clinical and translational research, represent the asset at key governance forums, and shape portfolio-level decision-making in oncology. Work across global cross-functional teams to advance innovative therapies within a matrixed biopharma environment.

GSK United States £242,250 – £403,750 pa

Head, Oncology Clinical Development - ADCs

Leads the clinical development strategy for antibody-drug conjugates (ADCs) in oncology, spanning early- to late-phase trials across multiple tumor types. Responsible for end-to-end asset development, including regulatory approval and launch readiness, with a focus on scientific rigor, innovation in trial design, and cross-functional collaboration. Engages with global health authorities, governance bodies, and external experts to shape clinical and translational strategies.

GSK US$242,250 – US$403,750 pa

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

This role involves developing, validating, and executing ligand-binding and cell-based assays to support mRNA medicine development. The candidate will generate pharmacodynamic and immunogenicity data in a regulated GcLP environment, manage critical reagent characterization, and contribute to clinical sample testing using Watson LIMS. The position emphasizes scientific rigor, regulatory compliance, and collaboration within a high-performance team advancing novel bioanalytical assays.

Moderna Oxford, United Kingdom

Hybrid Permanent

Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based

This role involves leading the development, qualification, and execution of complex cell-based immunoassays to support Moderna’s clinical trials across multiple therapeutic areas. The scientist will generate high-quality, reproducible data in compliance with GCP and GLP standards, while serving as a subject matter expert and collaborating with cross-functional teams. Emphasis is placed on innovation, scientific rigor, and advancing mRNA-based medicine through robust assay design and data analysis.

Moderna Oxford, United Kingdom

Hybrid Permanent

(Fixed Term) Manufacturing Associate I

Operate and maintain mRNA vaccine production equipment in compliance with cGMP and safety standards, executing manufacturing processes, troubleshooting equipment and digital systems, and supporting quality documentation and continuous improvement initiatives. Work within a cross-functional team to ensure timely batch release and operational excellence in a fast-paced, highly regulated environment.

Moderna Oxford, United Kingdom

On-site Temporary