Latest Metabolic Diseases Jobs

Senior Scientist or Associate Principal Scientist Metabolist Team

This role involves conducting advanced in vitro and ex vivo research to identify and validate therapeutic targets for obesity. The successful candidate will work in a dynamic, collaborative environment, designing and implementing experiments, analyzing data, and contributing to drug discovery projects across multiple sites.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

Senior Statistician I

The Senior Statistician I will lead statistical input into clinical and preclinical study design, analysis, and reporting within AstraZeneca’s CVRM team. This role involves developing robust statistical analysis plans, applying modelling and simulation techniques, and translating complex results into actionable insights for multidisciplinary teams. The position emphasizes methodological rigor, regulatory readiness, and collaboration across global therapy areas to accelerate evidence generation for innovative medicines.

AstraZeneca Cambridge, United Kingdom

Hybrid Permanent

Global Development Lead, Early Clinical Development, Internal Medicine

The Global Development Lead will drive clinical research for cardiometabolic diseases, creating and executing early clinical development strategies. They will work closely with cross-functional teams to translate pre-clinical observations into clinical experiments, ensuring medical and scientific excellence, and managing the delivery of clinical trial data and regulatory documents.

Pfizer Cambridge, United Kingdom

On-site Permanent

Global Development Lead, Early Clinical Development, Internal Medicine

The Global Development Lead will drive clinical research for cardiometabolic diseases, creating early clinical development strategies and leading the translation of pre-clinical observations into Phase 1/2 studies. They will work closely with cross-functional teams to ensure medical and scientific excellence, manage clinical trial execution, and engage with regulatory authorities and external collaborators.

Pfizer Sandwich, United Kingdom

On-site Permanent

Assoc Director, Statistical Programming

The Associate Director, Statistical Programming, leads all statistical programming aspects for one or more drug development programs, ensuring cross-functional collaboration, resource allocation, and regulatory compliance. They coordinate activities, mentor programmers, and represent the team in audits and Health Authority meetings.

Novartis London, United Kingdom

Hybrid Permanent

Head of DMPK

The Head of DMPK will lead the strategic direction of drug metabolism and pharmacokinetics, ensuring robust scientific excellence and predictive modeling. Key responsibilities include defining DMPK strategies, collaborating with data science teams, and leading a high-performing team.

Recursion London, United Kingdom £166,500 – £208,100 pa

Hybrid Permanent

Head of DMPK

The Head of DMPK will lead the DMPK strategy, ensuring scientific excellence and robust human dose projections. You will collaborate with data science and ML teams to refine predictive ADME models, support external partnerships, and develop a high-performing team.

Recursion United Kingdom US$284,900 – US$400,950 pa

Hybrid Permanent

Global Studies Asset Manager (GSAM)

The Global Asset Study Manager (GASM) at Roche/Genentech is responsible for the efficient execution of global clinical trials, ensuring consistency and compliance with IHC-GCP and Roche processes. Key responsibilities include coordinating study management, developing essential documents, driving innovation, and maintaining inspection readiness.

Roche Welwyn Hatfield, United Kingdom

On-site Permanent

Head of Medicinal Chemistry, Drug Design, London

As Head of Medicinal Chemistry, you will lead a team of 25 chemists in London, driving the development of novel drugs using cutting-edge AI and machine learning. You will provide strategic direction, mentor team members, and collaborate with AI/ML scientists to accelerate drug discovery and clinical candidate nomination.

Isomorphic Labs London, United Kingdom

On-site Permanent

Computational Drug Designer, London

As a Computational Drug Designer, you will work on cutting-edge drug discovery projects, applying AI and computational chemistry to design novel molecules. You will collaborate with interdisciplinary teams, contribute to scientific proposals, and mentor junior colleagues in a fast-paced, innovative environment.

Isomorphic Labs United Kingdom

Hybrid Permanent

ViiV Healthcare (GSK) Senior Director, Clinical Development

As a Senior Medical Director at ViiV Healthcare, you will lead the design and delivery of early development plans for HIV treatments, ensuring clinical excellence and medical governance across Phase 1-4 studies. You will collaborate with internal and external stakeholders to design, execute, and interpret clinical studies, focusing on long-acting medicines and ensuring patient safety and data integrity.

GSK United States

On-site Permanent

ViiV Healthcare (GSK) Senior Director, Clinical Development

This role involves leading the design and delivery of early development plans for HIV treatments, ensuring clinical excellence and medical governance across Phase 1-4 studies. You will collaborate with internal and external stakeholders to design, execute, and interpret clinical studies, ensuring patient safety and scientific excellence.

GSK

On-site Permanent

Scientist I, Molecular and Cell Biology

This role involves conducting cutting-edge research in molecular and cell biology, focusing on cell health and rejuvenation. Responsibilities include designing and executing experiments, developing new assays, and collaborating with multidisciplinary teams to advance translational projects and validate therapeutic targets.

Altos Labs Cambridge, United Kingdom £51,500 – £67,700 pa

On-site Permanent

Global Regulatory Affairs Associate Director (Cardio-Metabolic)

This role involves leading the development and submission of regulatory documents, providing strategic direction, and negotiating with health authorities to expedite approvals. The position also focuses on ensuring compliance and timely approval of new and marketed products, serving as a regulatory liaison throughout the product lifecycle.

Novartis London, United Kingdom

Hybrid Permanent

Senior Director Global Clinical Program Lead Cardiovascular & Renal

This role involves leading the clinical development of a medicine for cardiovascular and renal conditions, managing a cross-functional team, and ensuring compliance with regulatory standards. Responsibilities include strategic planning, clinical oversight, and authoring key documents for regulatory submissions and publications.

CSL Switzerland

On-site Permanent