Latest Gene Therapy Scientist Jobs

Spotlight

Senior Clinical Trial Case Manager

This role involves leading safety data review and pharmacovigilance activities within clinical trials, ensuring compliance with international regulations such as GxP. The individual will mentor team members, manage CAPAs, support regulatory inspections, and contribute to safety reporting and risk management. Key responsibilities include MedDRA coding, safety data analysis, and developing pharmacovigilance procedures to support global regulatory requirements.

CSL

On-site Permanent

Spotlight

Senior Computational Chemist, LNP Design

This role involves leading the computational design of lipid nanoparticles for nucleic acid delivery, using chemical and biophysical principles, AI tools, and molecular simulations. You will work closely with the experimental team to translate computational insights into testable strategies and refine formulations iteratively.

CureAge Therapeutics London, ENG, United Kingdom

Hybrid Permanent Part-time

Senior Scientist - ELN & Data Specialist, Global Technical Development

This role involves hands-on administration, configuration, and continuous improvement of an Electronic Lab Notebook (ELN) platform to support R&D and Technical Development laboratories. The scientist will define ELN standards, design workflows and templates, integrate systems, and develop data repositories to enable data-driven decision-making. Collaboration with cross-functional teams is essential to ensure compliance, data integrity, and effective use of the ELN across scientific operations.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Manager, PV Operations

This role leads global pharmacovigilance operations for a gene therapy company, overseeing safety case management, regulatory reporting, and compliance across clinical and post-marketing portfolios. The individual ensures robust, scalable processes and systems, including vendor oversight, safety database administration, and audit readiness. They play a key technical and operational role in SOP development, inspection preparedness, and cross-functional collaboration to support signal detection and risk management.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading and executing phase-appropriate bioanalytical strategies for immunogenicity and ligand binding assays (LBA) within Moderna’s mRNA-LNP therapeutic pipeline. The Principal Scientist will oversee assay development, validation, and sample analysis, ensuring regulatory compliance and scientific rigor across clinical programs. The position emphasizes collaboration with cross-functional teams, integration of emerging technologies including AI-enabled tools, and contribution to regulatory submissions and data interpretation in a GcLP-compliant environment.

Moderna Oxford, United Kingdom

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays (LBA) in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and GCP standards. The position plays a key role in clinical development by generating high-quality data to inform regulatory submissions and advance innovative medicines, with opportunities to engage in AI-enabled and digital analytical approaches.

Moderna

Hybrid Permanent

Global Research Program Manager

The Global Research Program Manager will drive internal operational efficiency, coordinate cross-team projects, manage key partnerships, and oversee the tools and operations that the technical teams rely on. This role involves optimizing processes, facilitating collaboration, and ensuring that the team can focus on pioneering research and development.

Basecamp Research London, United Kingdom

On-site Permanent

Market Product Lead

This role involves owning the peptide and protein platform as a commercial product, conducting market and competitive intelligence, defining target product profiles, and shaping the go-to-market strategy. The role requires a deep understanding of peptide therapeutics and the ability to bridge technical and commercial conversations with pharmaceutical partners.

Basecamp Research London, United Kingdom

On-site Permanent

Senior Manager/ Associate Director, Data Management

This role involves managing and overseeing clinical trial data, ensuring compliance with industry standards, and collaborating with cross-functional teams. Responsibilities include planning data management deliverables, liaising with vendors, and maintaining inspection readiness.

Autolus United States

Senior Manager/ Associate Director, Data Management

Work with usOur team are passionate in the pursuit of excellence and in pushing the boundaries of cancer therapy and Autoimmune disease to deliver life-changing treatments to patients.Whilst working at Autolus you will enjoy a flexible, diverse and dynamic working...

Autolus

Director, Translational Medicine Expert (Neurodegeneration)

This role involves leading the translational strategy for neurodegenerative programs, from preclinical research to early clinical development. Responsibilities include biomarker strategy, clinical trial design, and cross-functional leadership, with a focus on integrating patient-centered approaches and advancing scientific collaborations.

Novartis London, United Kingdom

Director, Search & Evaluation Early TA Lead (Haem)

Leads external innovation sourcing and evaluation in Haematology, identifying preclinical to Phase 1 assets, driving due diligence, and shaping early partnering strategies. Works within the Therapeutic Area Leadership Team to advance high-potential opportunities and collaborates with Business Development to execute deals. Engages with biotech, academia, and investors to build a robust pipeline.

CSL

Postdoctoral Research Fellow in Molecular Mechanisms of Eukaryotic Transcription

This role involves investigating the molecular mechanisms of eukaryotic transcription, focusing on how phosphorylation regulates RNA polymerase II (Pol II) transcription, RNA processing, and gene expression. The project combines biochemistry, structural biology, cell biology, and functional genomics, with opportunities to develop and combine experimental approaches.

University of Sussex Falmer, South East England, United Kingdom £38 – £46 pa

Contract

Data Engineer (Forward Deployed)

This role involves collaborating with scientists and engineers to build robust, reproducible data pipelines for diverse research projects. You will ensure datasets are accurate, version-controlled, and ready for machine learning, working hands-on with cutting-edge technologies and methodologies.

Ellison Institute of Technology Oxford, United Kingdom

Hybrid Permanent

Vector Design Lead - Plant Biology Institute

This role leads the design and delivery of transformation-ready vectors and genome editing reagents for crop improvement programs, focusing on molecular construct development for gene editing and transgenic approaches in species like corn and wheat. The position establishes industrial-grade design standards, ensures technical robustness and regulatory alignment, and integrates with high-throughput transformation pipelines. It involves close collaboration with genotyping, automation, and commercial teams to enable scalable, traceable, and auditable vector development from concept to release.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent

Research Assistant in Molecular Virology

The role involves conducting molecular virology research, focusing on the interactions between viruses and host cells, particularly in the context of cellular oxygen sensing. Responsibilities include maintaining viral cultures, performing molecular biology techniques, and contributing to experimental design and data analysis.

University of Oxford Oxford, South East England, United Kingdom £35 – £37 pa

Contract