Biotechnology Jobs in Oxford

• Oxford
• Hybrid
• Permanent

Builds AI agents on the LifeAI platform that help scientists plan and carry out research, connecting models, tools, data and compute. Focuses on agent skills, tool integrations and evaluations for protein design and enzyme engineering, enabling agents to propose workflows, explain assumptions and produce candidates for experimental testing. Works with scientific product managers, researchers and platform teams, reporting to the Lead Software Engineer.

LifeAI

• Oxford
• On-site
• Permanent

Conducts class-targeted metabolomics and metabolic engineering of plant natural products, using extraction, purification, mass spectrometry and computational structural assignment to support cell-based production of food and medicines. Works in a highly collaborative institute alongside AI and robotics teams on high-throughput analytical procedures, with stage-gated milestones and an active role in IP generation.

• Oxford
• On-site
• Senior

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

MSD · LIMS · eLNB +1

• Oxford
• On-site
• Mid-level

Hands-on automation engineering role supporting drug product packaging and drug substance manufacturing at a new mRNA facility. Involves commissioning and optimising Emerson DeltaV and Allen-Bradley/Rockwell PLC systems, automated labelling and secondary packaging equipment, plus GxP validation, root cause analysis and lifecycle documentation. Works independently as a technical specialist across manufacturing, engineering, quality and digital teams.

Emerson DeltaV · Allen-Bradley · Rockwell Automation +7

• Oxford
• On-site
• Senior
• Permanent

Hands-on role building AI-driven autonomous laboratories that integrate experimental science, robotics and machine learning to design, execute and optimise experiments dynamically. The scientist develops self-driving workflows, particularly for deployment environments where automation scientists are not readily available.

AI

• Oxford
• On-site
• Senior

Hands-on role designing, prototyping and characterising novel MEMS devices and sensor interfaces for next-generation nanopore sequencing, taking concepts from proof-of-concept to integrated multi-channel sensing systems. Works closely with a Senior Electronics R&D Engineer and external fabrication partners, tackling microfabrication, materials, device architecture and MEMS-electronics integration while helping establish MEMS engineering capabilities for a growing multidisciplinary team.

Oracle Cloud

• Oxford
• On-site
• Entry level
• Permanent

Postdoctoral role in the joint Monera project, building multi-modal generative models of whole organisms starting with E. coli. You will perform high-throughput genome engineering to generate diverse microbial strains and design scalable measurement strategies, working in an integrated computational and experimental team alongside AI scientists.

Escherichia coli

• Oxford
• On-site
• Permanent

Develop and apply computational methods to analyse complex plant genomes, building pipelines for genome assembly, annotation and variant analysis. Work closely with bioinformatics engineers and research scientists to translate biological questions into reproducible workflows and prioritise targets for crop engineering.

• Oxford
• On-site
• Permanent

Develops and scales experimental platforms to test engineered protein variants for photosynthetic efficiency, photoprotection and carbon assimilation. Combines transient plant expression, molecular biology and high-throughput photosynthetic phenotyping, working with computational scientists and protein engineers to inform go/no-go decisions for crop transformation.

• Oxford
• On-site
• Senior
• Permanent

Designs and engineers plant specialised metabolism in cell cultures to produce high-value natural products for health and medicine, applying synthetic biology to optimise biosynthetic pathway flux and product tolerance. Works with AI and robotics teams on model-driven engineering and stage-gated milestones, with a focus on IP generation and translating research into commercial solutions.

• Oxford
• On-site
• Senior
• Permanent

Lead the development of a plant cell-based screening platform to evaluate carbon fixation, using quantitative methods and CRISPR-based genome editing in suspension cultures. Apply iterative design-build-test-learn cycles to identify improved photosynthesis enzyme variants and engineered pathways, advancing promising candidates into whole plants. Contribute to IP generation and collaborate across multidisciplinary teams.

CRISPR

• Oxford
• Hybrid
• Senior
• Permanent

Builds and operates high-performance GPU training and inference clusters, focusing on scheduling, isolation and automated lifecycle management. Optimises high-throughput data paths, I/O, caching and Lustre storage, and profiles bottlenecks across compute, network and orchestration layers. Works with research and data teams on capacity planning, quotas and ML experimentation pipelines.

Lustre

• Oxford
• On-site
• £40,000 pa
• Senior
• Permanent

Develops and optimises LC-MS workflows for low-input and single-cell proteomics and/or metabolomics, supporting researchers across the institute with experiment design, method development, data acquisition and interpretation. Works closely with bioinformatics, scientific computing and AI/ML teams, and helps build SOPs and training material for single-cell MS capability.

LC-MS · Flow Cytometry · Sequencing +5

• Oxford
• On-site
• £40,000 pa
• Entry level
• Permanent

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

OrthoRep

• Oxford
• On-site
• £40,000 pa
• Entry level
• Permanent

Designs and troubleshoots experiments in continuous evolution, engineering orthogonal replication systems for targeted gene evolution while preserving host viability. Involves computational analysis of complex datasets, publishing high-quality research, mentoring junior staff, and pursuing IP and translational opportunities within a new Oxford institute.