Biotechnology Jobs

24 jobs for “Protein Engineer”

Results

CureAge Therapeutics logo
Featured

Senior Computational Chemist, LNP Design

Last week

CureAge Therapeutics London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Hybrid Permanent Part-time
Alloy Therapeutics UK Ltd logo
Featured

Scientist I – Molecular Biology

3 days ago

Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

On-site Permanent

Senior Scientist I

2 weeks ago

Evotec Macclesfield

Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.

On-site Permanent

Machine Learning Scientist

4 months ago

Latent Labs London

Architect novel generative models to design functional proteins, working in an interdisciplinary team of ML researchers, protein engineers and biologists. Split roughly 90/10 between building and evaluating models against wet lab results and self-development, with heavy emphasis on data pipelines, cloud training and production-quality code.

Hybrid Permanent
Ellison Institute of Technology logo

(Senior) Group Leader, Nitrogen Fixation - Plant Biology Institute

9 months ago

Ellison Institute of Technology Oxford

Lead a flagship research programme in biological nitrogen fixation, engineering novel nitrogen-fixing systems into plants through metabolic and protein engineering. Recruit and manage a team of postdocs and PhD students, drive stage-gated translational research from lab to field, and build collaborations across EIT Oxford and commercial partners.

On-site Permanent

Principal Medical Scientist (Biopharmaceutical)

2 weeks ago

ISR Recruitment Oxford £520 – £532 pd

Lead a laboratory-based immunology team, designing in vitro pharmacology assays and coordinating in vivo efficacy studies with CROs to advance biologic therapies for autoimmune diseases. Involves target identification, ex vivo profiling, and cross-functional work with protein engineering, biomarkers and translational medicine, plus IND documentation and publications.

On-site Contract

Member of Technical Staff, Applied AI

8 months ago

Latent Labs London

Work at the interface between frontier generative models and pharmaceutical/biotech customers, deploying, adapting and fine-tuning models in customer environments. Build production-grade API integrations, model-serving infrastructure and ML data pipelines, while acting as technical point of contact for partners. Combines deep ML research with customer-facing delivery in an interdisciplinary team.

Hybrid Permanent

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Principal Scientist, Inflammation Research

3 months ago

Gilead Sciences Oxford

Lead a team of scientists developing novel biologic therapies for autoimmune disease, overseeing in vitro and in vivo pharmacology studies for lead and early discovery programs. Collaborate across immunology, protein engineering, translational medicine and biomarkers to deliver data packages for progression to development, while mentoring staff and contributing to INDs and patents.

Senior Software Engineer - Cloud

3 weeks ago

Nuclera Cambridge

Full-stack engineer building customer-facing cloud and instrument software plus internal tools supporting in-house protein screening services. Owns features end to end, from gathering requirements with biologists and stakeholders through technical design, implementation and testing across backend, frontend, dev-ops and QA.

Hybrid Permanent

Lecturer / Associate Professor in Artificial Intelligence for Biomolecular Design & Molecular Interactions

5 days ago

UCL London £68,284 – £76,244 pa

Develops and leads an AI-driven research programme in biomolecular design and molecular interactions, spanning protein-ligand, protein-protein and protein-nucleic acid systems. Combines structural biology, biophysics, quantitative biology and machine learning, while teaching computational biology and biomolecular design at undergraduate and postgraduate level, including a new MRes in AI for Bioscience.

Hybrid Permanent
Roche logo

Machine Learning Scientist - Quantum Chemistry

4 months ago

Roche Welwyn

Builds physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Works in a small-molecule team within AI for Drug Discovery, creating synthetic quantum-mechanics datasets and deployable pipelines that feed molecular-design tools across Roche, with a strong publication and open-source focus.

Hybrid Permanent
Roche logo

Machine Learning Scientist - Quantum Chemistry

4 months ago

Roche Basel, Switzerland

Build physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Work in a small-molecule team within AI for Drug Discovery, creating synthetic QM datasets and deployable, scalable pipelines that feed molecular-design tools across Roche, alongside computational and experimental scientists.

Hybrid Permanent

Market Product Lead

Last week

Basecamp Research London

Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.

On-site Permanent

Senior / Principal Computational Biologist, AI Safety

Last week

Lila Sciences London US$268,000 – US$384,000 pa

Conducts original computational biology research for AI safety, investigating how LLMs, specialised biological models, agents and automated laboratories combine to change what is biologically feasible. Spans protein and nucleic-acid design, cellular systems and biological delivery, translating risk judgments into dual-use policy boundaries, evaluation priorities and mitigation requirements alongside threat modellers and red-teamers.

Isomorphic Labs logo

Senior Research Investigator, (Biologics Pharmacology), London

Last week

Isomorphic Labs London

Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.

Hybrid

Senior Scientist, R&D

2 months ago

Basecamp Research London

Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.

On-site Permanent

Senior Scientist (Expression)

Last month

Evotec Macclesfield

Designs and executes work plans for early drug discovery projects within a Protein Sciences team, supporting multiple projects and presenting results to clients. Hands-on role focused on recombinant protein expression using insect cell systems such as BEVS, S2 and Sf9, including construct design, baculovirus generation and troubleshooting difficult targets like membrane proteins.

On-site Permanent