37 jobs for “Protein Engineer”
Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa
Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.
CureAge Therapeutics London
Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.
Evotec Macclesfield
Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.
Latent Labs London
Architect novel generative models to design functional proteins, working in an interdisciplinary team of ML researchers, protein engineers and biologists. Split roughly 90/10 between building and evaluating models against wet lab results and self-development, with heavy emphasis on data pipelines, cloud training and production-quality code.
Ellison Institute of Technology Oxford
Develops and optimises high-throughput enzyme assays to characterise plant protein variants from AI-assisted design and evolutionary discovery. Works with computational scientists, automation engineers and roboticists to build scalable protein expression, purification and biochemical characterisation pipelines, informing protein engineering and crop yield decisions.
Ellison Institute of Technology Oxford
Lead a flagship research programme in biological nitrogen fixation, engineering novel nitrogen-fixing systems into plants through metabolic and protein engineering. Recruit and manage a team of postdocs and PhD students, drive stage-gated translational research from lab to field, and build collaborations across EIT Oxford and commercial partners.
Latent Labs London
Work at the interface between frontier generative models and pharmaceutical/biotech customers, deploying, adapting and fine-tuning models in customer environments. Build production-grade API integrations, model-serving infrastructure and ML data pipelines, while acting as technical point of contact for partners. Combines deep ML research with customer-facing delivery in an interdisciplinary team.
Evotec Abingdon
Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.
EMBL-EBI Saffron Walden £3,452 pm
Designs and develops software and APIs for the UniProt protein data services and website, serving a global scientific community. Also handles design, maintenance and monitoring of the website's cloud infrastructure, with a focus on scalability, well-tested code and distributed big-data processing. Works in a dynamic interdisciplinary team of engineers and bioinformaticians alongside biologists.
Nuclera Cambridge
Full-stack engineer building customer-facing cloud and instrument software plus internal tools supporting in-house protein screening services. Owns features end to end, from gathering requirements with biologists and stakeholders through technical design, implementation and testing across backend, frontend, dev-ops and QA.
UCL London £68,284 – £76,244 pa
Develops and leads an AI-driven research programme in biomolecular design and molecular interactions, spanning protein-ligand, protein-protein and protein-nucleic acid systems. Combines structural biology, biophysics, quantitative biology and machine learning, while teaching computational biology and biomolecular design at undergraduate and postgraduate level, including a new MRes in AI for Bioscience.
Roche Welwyn
Builds physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Works in a small-molecule team within AI for Drug Discovery, creating synthetic quantum-mechanics datasets and deployable pipelines that feed molecular-design tools across Roche, with a strong publication and open-source focus.
Roche Basel, Switzerland
Build physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Work in a small-molecule team within AI for Drug Discovery, creating synthetic QM datasets and deployable, scalable pipelines that feed molecular-design tools across Roche, alongside computational and experimental scientists.
Recursion Salt Lake City, United States
Develop, optimize and validate cell-based and biochemical assays for automated high-throughput screening, running workflows at scale across 384- and 1536-well formats. Work in a cross-disciplinary team with biologists, automation and data scientists, documenting methods so assays transfer reliably. A 9-month contractor role, Monday to Friday, 9am-5pm.
CSL Maidenhead
This role involves leading the R&D Resource and Schedule Management capabilities, defining the mission, governance, and operating model. Responsibilities include capacity and demand management, scenario planning, and stakeholder engagement to ensure alignment with organizational goals and portfolio priorities.
Isomorphic Labs London
Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.
Basecamp Research London
Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.
