Biotechnology Jobs

CureAge Therapeutics · London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Alloy Therapeutics UK Ltd · Cambridge · £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

Ellison Institute of Technology · Oxford

Develops and optimises high-throughput enzyme assays to characterise plant protein variants from AI-assisted design and evolutionary discovery. Works with computational scientists, automation engineers and roboticists to build scalable protein expression, purification and biochemical characterisation pipelines, informing protein engineering and crop yield decisions.

Evotec · Abingdon

Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.

Ellison Institute of Technology · Oxford

Builds and leads a molecular biology and synthetic biology function within a plant science institute, setting technical strategy for high-throughput assays, sequencing-based readouts, CRISPR guide design and multiplex editing. Acts as a responsive core facility, coaching scientists on experimental design and integrating with bioinformatics, tissue culture and phenotyping teams. Combines deep technical direction with people leadership rather than routine bench work.

Vertex Pharmaceuticals · Oxford

Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.

Moderna · Oxford

Designs and delivers immunogenicity and bioanalytical strategies for regulated clinical programmes, developing ADA, nAb, PK and PD assays using ELISA, MSD and cell culture. Works with multidisciplinary teams to validate assays, manage reagents and SOPs, and integrate digital and AI-enabled tools. Site-based at Harwell within a growing mRNA-focused team.