Biotechnology Jobs

22 jobs for “Protein Engineer”

Results

CureAge Therapeutics logo
Featured

Senior Computational Chemist, LNP Design

Last week

CureAge Therapeutics London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Hybrid Permanent Part-time
Alloy Therapeutics UK Ltd logo
Featured

Scientist I – Molecular Biology

3 days ago

Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

On-site Permanent

Principal Medical Scientist (Biopharmaceutical)

2 weeks ago

ISR Recruitment Oxford £520 – £532 pd

Lead a laboratory-based immunology team, designing in vitro pharmacology assays and coordinating in vivo efficacy studies with CROs to advance biologic therapies for autoimmune diseases. Involves target identification, ex vivo profiling, and cross-functional work with protein engineering, biomarkers and translational medicine, plus IND documentation and publications.

On-site Contract

VP Head of Therapeutics Design

2 weeks ago

Evotec Abingdon

Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.

On-site Permanent

Principal Scientist, Inflammation Research

3 months ago

Gilead Sciences Oxford

Lead a team of scientists developing novel biologic therapies for autoimmune disease, overseeing in vitro and in vivo pharmacology studies for lead and early discovery programs. Collaborate across immunology, protein engineering, translational medicine and biomarkers to deliver data packages for progression to development, while mentoring staff and contributing to INDs and patents.

Ellison Institute of Technology logo

Head of Molecular Engineering, Plant Biology Institute

3 weeks ago

Ellison Institute of Technology Oxford

Builds and leads a molecular biology and synthetic biology function within a plant science institute, setting technical strategy for high-throughput assays, sequencing-based readouts, CRISPR guide design and multiplex editing. Acts as a responsive core facility, coaching scientists on experimental design and integrating with bioinformatics, tissue culture and phenotyping teams. Combines deep technical direction with people leadership rather than routine bench work.

On-site Permanent

Market Product Lead

Last week

Basecamp Research London

Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.

On-site Permanent

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Senior / Principal Computational Biologist, AI Safety

Last week

Lila Sciences London US$268,000 – US$384,000 pa

Conducts original computational biology research for AI safety, investigating how LLMs, specialised biological models, agents and automated laboratories combine to change what is biologically feasible. Spans protein and nucleic-acid design, cellular systems and biological delivery, translating risk judgments into dual-use policy boundaries, evaluation priorities and mitigation requirements alongside threat modellers and red-teamers.

CSL logo

Associate Director, R&D Project Management - Resource and Schedule Lead

Last week

CSL Maidenhead

This role involves leading the R&D Resource and Schedule Management capabilities, defining the mission, governance, and operating model. Responsibilities include capacity and demand management, scenario planning, and stakeholder engagement to ensure alignment with organizational goals and portfolio priorities.

VP Head of AI

2 weeks ago

Evotec Abingdon

Leads Evotec's consolidated AI Accelerator, owning machine learning, generative and agentic AI, and therapeutic hypothesis groups. Sets the AI vision and roadmap, makes build/buy/partner decisions for the AI stack, and turns proprietary multi-omics and experimental data into predictive models and reusable IP. Acts as the senior external technical voice for AI in drug discovery.

Permanent

Principal Scientist

3 weeks ago

Nexus Life Sciences Belfast £50,000 – £60,000 pa

Leads a Clinical Method Development and Validation team, overseeing bioanalytical method delivery for a New Product Development programme. Provides technical leadership in a GLP-compliant lab, acting as expert in extraction techniques and optimising HPLC, UPLC and LCMSMS systems while mentoring the team.

CSL logo

Associate Director, Biostatistics

2 days ago

CSL Maidenhead US$212,000 – US$251,000 pa

Leads the full statistical contribution to a clinical development programme, defining statistical strategy for trial design, analysis and regulatory submissions, and representing Biostatistics in interactions with the FDA, EMA and PMDA. Also manages outsourcing to CROs/FSPs and contributes to governance and development-plan decisions across therapeutic areas.

Hybrid

Executive Director, Oxford DMPK

Yesterday

Vertex Pharmaceuticals Oxford

Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.

On-site

Chief Scientist, Modern Drug Discovery

Last month

IQVIA Cambridge

A senior scientific leadership role shaping and delivering a drug discovery strategy, driving adoption of AI-assisted design, predictive modelling, automation and computational science across a diverse portfolio. The post-holder mentors multidisciplinary teams spanning biology, chemistry, protein design, pharmacology and translational sciences, and acts as a scientific ambassador in client engagements, proposals and partnerships.

Permanent Flexible