28 jobs for “Protein Engineer”
Ellison Institute of Technology Oxford £40,000 pa
Develops generative protein design models that capture enzyme dynamics and function, designing conformationally dynamic catalysts. Runs computational and statistical analyses, publishes findings, and collaborates with in vivo evolution teams across the institute. Also mentors PhD students and research assistants and pursues translational and IP opportunities.
Ellison Institute of Technology Oxford
Design and conduct experiments on nanopore technologies, single-molecule analysis, and 3D tissue engineering, spanning chemistry, biology, physics and engineering. Postdocs lead development of emerging biotech methods, publish impactful research, and mentor junior researchers within a 100+ researcher institute.
Evotec Macclesfield
Designs and executes work plans for early drug discovery projects within a Protein Sciences team, supporting multiple projects and presenting results to clients. Hands-on role focused on recombinant protein expression using insect cell systems such as BEVS, S2 and Sf9, including construct design, baculovirus generation and troubleshooting difficult targets like membrane proteins.
Nuclera Cambridge
Formulate, dispense and quality-control reagents for a protein discovery platform, operating lab equipment such as pipettes, centrifuges and UPLC systems. The role covers batch documentation, inventory management via ERP and troubleshooting production deviations, working closely with R&D, QA and Supply Chain in a fast-paced lab environment.
Sartorius Glasgow
Performs laboratory techniques under GMP conditions, including cell-based assays, ELISAs and protein characterisation, to test biological products such as monoclonal antibodies, cell and gene therapies and vaccines. Also manages stock and reagents, maintains traceability records, and prepares controlled documentation like SOPs and risk assessments within a nine-person team.
CSL Maidenhead
Acts as case management subject matter expert for assigned clinical trials, overseeing safety reporting plans, vendor performance and ICSR compliance. Leads pharmacovigilance processes, supports GxP inspections and audits, and provides study-specific training to vendors and internal teams. Requires deep PV and regulatory knowledge in a multinational pharmaceutical setting.
Isomorphic Labs London
Contribute to the design of novel large-molecule therapeutics by applying computational and machine learning methods to predict biologics properties such as affinity, developability and immunogenicity from sequence. Work within an interdisciplinary computational sciences team alongside ML and biologics discovery experts, benchmarking models, analysing lab data and shaping data-generation strategies for active learning.
Francis Crick Institute London £47,500 pa
Investigates how protein machines remodel microtubules using cryo-electron microscopy, protein reconstitution and fluorescence microscopy. As an early member of a new lab, you will shape the research programme, establish experimental approaches and develop scientific independence while working closely with the group leader.
University of Oxford Oxford £39,424 – £43,984 pa
Carries out laboratory research on synthetic genome DNA assembly, generating constructs and testing new approaches using recombinant DNA methylases. Involves molecular cloning, long DNA molecule extraction, bacterial culture and recombinant protein production and purification, with scope for some bioinformatic analysis. Based in a well-equipped Oxford lab, collaborating on translation of synthetic chloroplast genomes into crop plants such as potato and wheat.
Vertex Pharmaceuticals Oxford
A 12-month laboratory-based industrial placement within the Structural Biology & Biophysics department, working at the interface with Biology on a collaborative project. The role involves membrane protein preparation and reconstitution into lipid-based model systems, functional characterisation using electrophysiology, and interpreting biochemical and biophysical data to support early drug discovery.
CSL Opfikon, Switzerland
Leads safety review and end-to-end signal detection across a product's lifecycle, using quantitative and qualitative methods alongside Global Safety Leads. Contributes to aggregate safety reports, risk management plans and regulatory responses, and mentors junior PVS staff. Works cross-functionally with Development, Medical Affairs and Regulatory teams on vaccine and national-significance products.
Moderna Oxford
Develops, validates and runs ligand-binding and cell-based bioanalytical assays generating pharmacodynamic and immunogenicity data for clinical mRNA programmes. Works in a GcLP-regulated lab using Thermo Watson LIMS and electronic notebooks, handling clinical samples, critical reagents, SOPs and validation reports while partnering with Clinical Operations and Sample Management.
CSL Maidenhead
Leads safety surveillance and signal detection across a product's lifecycle, reviewing clinical and post-marketing data and contributing to aggregate safety reports and risk management plans. Partners with Global Safety Leads and cross-functional teams, mentors junior scientists, and supports regulatory responses.
