Biotechnology Jobs

CureAge Therapeutics · London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Alloy Therapeutics UK Ltd · Cambridge · £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

Ellison Institute of Technology · Oxford · £40,000 pa

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

ISR Recruitment · Oxford · £520 – £532 pd

Lead a laboratory-based immunology team, designing in vitro pharmacology assays and coordinating in vivo efficacy studies with CROs to advance biologic therapies for autoimmune diseases. Involves target identification, ex vivo profiling, and cross-functional work with protein engineering, biomarkers and translational medicine, plus IND documentation and publications.

Gilead Sciences · Oxford

Lead a team of scientists developing novel biologic therapies for autoimmune disease, overseeing in vitro and in vivo pharmacology studies for lead and early discovery programs. Collaborate across immunology, protein engineering, translational medicine and biomarkers to deliver data packages for progression to development, while mentoring staff and contributing to INDs and patents.

University of East Anglia · Norwich · £21,805 pa

A four-year PhD project using engineering biology to develop bacterial and human ferritin nanocages for encapsulating small molecules, peptides and proteins, with applications in biocatalysis and therapeutics. The work spans protein purification, bioanalytical methods, spectroscopy, mass spectrometry and microscopy, targeting enzymes such as hydrogenase and targeted molecular delivery. Based in the Le Brun lab at UEA's School of Chemistry, Pharmacy and Pharmacology.

Ellison Institute of Technology · Oxford · £40,000 pa

Develops generative protein design models that capture enzyme dynamics and function, designing conformationally dynamic catalysts. Runs computational and statistical analyses, publishes findings, and collaborates with in vivo evolution teams across the institute. Also mentors PhD students and research assistants and pursues translational and IP opportunities.

University of Exeter · Exeter · £21,805 pa

An interdisciplinary PhD studentship combining computational genomics at Exeter with stem-cell biology and CRISPR editing at Cambridge. The student will analyse whole-genome sequencing data from large multi-ancestry cohorts, integrate genetic signals with epigenetic maps and AI tools like AlphaGenome, and build iPSC-derived visceral and subcutaneous adipocyte models to functionally test prioritised regulatory variants.

University of Sussex · Brighton · £38,784 – £46,049 pa

Investigates how phosphorylation regulates RNA polymerase II transcription, RNA processing and gene expression, combining biochemistry, structural biology, cell biology and functional genomics. The role involves maintaining mammalian cell culture, generating degron-tagged cell lines, transcriptome analyses and in vitro transcription reconstitution, with scope to develop independent ideas within a collaborative group.

Basecamp Research · London

Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.

Lila Sciences · London · US$268,000 – US$384,000 pa

Conducts original computational biology research for AI safety, investigating how LLMs, specialised biological models, agents and automated laboratories combine to change what is biologically feasible. Spans protein and nucleic-acid design, cellular systems and biological delivery, translating risk judgments into dual-use policy boundaries, evaluation priorities and mitigation requirements alongside threat modellers and red-teamers.

Imperial College London · London · £48,246 – £58,318 pa

Supports the production and characterisation of recombinant proteins for molecular glue discovery, focusing on expression, purification and characterisation using mammalian cell systems. Contributes to biochemical or biophysical assay development and helps run the laboratory day to day, including equipment upkeep, consumables and waste disposal, within a multidisciplinary chemical biology and proteomics team.

Sartorius · Glasgow

Performs laboratory techniques under GMP conditions, including cell-based assays, ELISAs and protein characterisation, to test biological products such as monoclonal antibodies, cell and gene therapies and vaccines. Also manages stock and reagents, maintains traceability records, and prepares controlled documentation like SOPs and risk assessments within a nine-person team.

Nexus Life Sciences · Belfast · £50,000 – £60,000 pa

Leads a Clinical Method Development and Validation team, overseeing bioanalytical method delivery for a New Product Development programme. Provides technical leadership in a GLP-compliant lab, acting as expert in extraction techniques and optimising HPLC, UPLC and LCMSMS systems while mentoring the team.

Francis Crick Institute · London · £47,500 pa

Investigates how protein machines remodel microtubules using cryo-electron microscopy, protein reconstitution and fluorescence microscopy. As an early member of a new lab, you will shape the research programme, establish experimental approaches and develop scientific independence while working closely with the group leader.

University of Oxford · Oxford · £39,424 – £43,984 pa

Carries out laboratory research on synthetic genome DNA assembly, generating constructs and testing new approaches using recombinant DNA methylases. Involves molecular cloning, long DNA molecule extraction, bacterial culture and recombinant protein production and purification, with scope for some bioinformatic analysis. Based in a well-equipped Oxford lab, collaborating on translation of synthetic chloroplast genomes into crop plants such as potato and wheat.

Vertex Pharmaceuticals · Oxford

A 12-month laboratory-based industrial placement within the Structural Biology & Biophysics department, working at the interface with Biology on a collaborative project. The role involves membrane protein preparation and reconstitution into lipid-based model systems, functional characterisation using electrophysiology, and interpreting biochemical and biophysical data to support early drug discovery.