76 jobs
Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa
Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.
CureAge Therapeutics London
Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.
Isomorphic Labs London
Lead all externalised drug discovery and preclinical lab operations, building and scaling a global CRO infrastructure for an AI-first drug design platform. Oversee experimental throughput, data QC and turnaround times, embed data-generation-by-design standards, and manage vendor governance, budgets and a team of CRO Scientific Leads, Operations Managers and Compound Managers.
Genomics London
Owns the data sourcing and partnerships framework, scanning the scientific landscape for new data modalities and cohorts, negotiating access and commercial terms with biobanks, health networks and TechBios, and building business cases for data investments. Works with engineering leadership to operationalise new data sources and partners with legal, commercial and scientific leadership. Requires deep population/statistical genetics expertise and experience leading multi-institutional consortia.
Orchard Therapeutics London
Safety expert serving as global PV lead for gene therapy products across investigational and marketed phases, owning benefit-risk strategy, aggregate reports (PSURs, DSURs) and risk management plans. Also acts as medical monitor, providing clinical oversight, real-time AE/SAE review and signal detection in close collaboration with cross-functional teams and health authorities.
Novartis London £83,930 – £155,870 pa
Supports the development, launch and continuous improvement of AI-powered products, working alongside Line Function Product Owners and cross-functional teams to translate product vision and strategy. Manages the product lifecycle from MVP through scaling, tracking budget and value metrics, and collaborating with DDIT and external parties on delivery and handover to maintenance.
Novartis London
Leads end-to-end translational strategy for neurodegenerative and neuromuscular programs, bridging preclinical research to Phase 1–2 clinical development. Accountable for biomarker strategy, clinical endpoint selection and early-phase trial design, and serves as the Translational Medicine representative within global cross-functional project and clinical trial teams.
GSK London
Lead statistical planning and delivery across oncology clinical programs, designing trials and analyses that shape development and regulatory strategy. Work with clinical, regulatory, safety, data science and commercial teams, using Bayesian methods and simulation in R or Python, while mentoring statisticians.
GSK USA - Pennsylvania - Upper Providence
Lead statistical planning and delivery across oncology clinical programs, designing trials and analyses that shape development and regulatory strategy. Work with clinical, regulatory, safety, data science and commercial teams, applying Bayesian methods, simulations and advanced modelling in R or Python, while mentoring statisticians.
Moderna London
Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and shape global regulatory approaches across cross-functional matrix teams.
Moderna London
Shape global CMC regulatory strategy for an innovative mRNA medicines portfolio, driving international submissions and health authority interactions. Prepare and review CMC sections of regulatory filings, advise Manufacturing and Quality teams, and oversee multiple development programs. An individual contributor role with global reach, working alongside teams using digital and Generative AI tools.
Relation Therapeutics London
Senior project manager role coordinating a multi-year osteoporosis drug discovery programme across target ID, hit-to-lead, lead optimisation and candidate selection. Involves orchestrating matrixed wet lab, ML, data science and engineering teams plus CROs, managing plans, budgets, risks and governance, and translating scientific objectives into integrated timelines and milestones.
Relation Therapeutics London
Lead the team behind hybrid on-prem and cloud compute infrastructure, Kubernetes clusters, and scientific compute environments supporting ML and drug discovery. Own platform strategy, CI/CD maturity, observability, and security controls for sensitive patient-derived data, reporting to the VP of Engineering.
Recursion Remote Opportunity - United Kingdom £136,500 – £167,200 pa
Lead clinical pharmacology and pharmacometrics strategy across a portfolio of rare disease and oncology programs, serving as the clinical pharmacology lead for regulatory interactions and study design from Phase 1-3. Perform and oversee modeling and simulation with tools such as WinNonlin, Monolix, NONMEM and R, and author regulatory sections for IBs, INDs and NDAs. Part of a Pharmacometrics team spanning clinical pharmacology, pharmacometrics and translational modeling, working end-to-end across discovery and development.
Recursion Salt Lake City, United States US$200,000 – US$220,500 pa
Lead a team of computational biologists in early discovery, acting as a player-coach who balances hands-on analysis with mentorship. Integrate phenomics, transcriptomics, genomics and proteomics data to nominate oncology and immunology targets, define validation criteria and precision medicine strategies, partnering with biologists, engineers and translational experts.
AstraZeneca Gaithersburg, United States US$218,330 – US$327,494 pa
Leads competitive intelligence for AstraZeneca's oncology R&D, owning delivery of clinical and commercial analysis that shapes therapy-area strategy and portfolio investment decisions. Works with a specialist team and senior leadership, translating complex data into insights and challenge. Requires oncology, clinical or investment analysis background.
AstraZeneca Cambridge, United States US$218,330 – US$327,494 pa
Leads competitive intelligence for AstraZeneca's oncology pipeline, delivering clinical and commercial analysis that shapes therapy-area strategy and investment decisions. Partners with senior leadership and cross-functional teams, providing respectful challenge and insight into the evolving oncology landscape. Requires oncology, clinical research or investment analysis background with strong communication and influence skills.
