Biomolecular NMR Specialist

Exciting Opportunity: Biomolecular NMR Spectroscopist

Are you a scientist who genuinely enjoys working hands‑on with proteins and NMR? This organisation is looking for a Biomolecular NMR Spectroscopist to strengthen their Molecular Sciences capability, supporting early‑stage drug discovery through high‑quality protein NMR data and assay development.

Job Title: Biomolecular NMR Spectroscopist

Vacancy Type: Fixed‑Term Contract (3 Years)

Location: Cambridge

Salary: DOE

The Role of the Biomolecular NMR Spectroscopist

In this role, you will be embedded within a specialist NMR group, supporting fragment‑based drug discovery programmes across oncology and CNS targets. The position is strongly focused on protein NMR, from protein production through to screening, assay development, and data interpretation.

Your responsibilities will include:

Designing, setting up, and running protein‑observed and ligand‑observed NMR experiments

Supporting NMR‑based fragment screening campaigns and characterising protein-ligand interactions

Expressing and purifying isotopically labelled proteins for NMR studies

Generating robust, high‑quality data on binding affinity, kinetics, and mechanism

Analysing and clearly communicating results to multidisciplinary project teams

You will work with a modern in‑house NMR suite, supporting high‑impact discovery projects while collaborating closely with chemists, biophysicists, and project scientists.

The Ideal Candidate for the Biomolecular NMR Spectroscopist Role

This role is best suited to someone with deep, hands‑on protein NMR experience. To succeed, you will bring:

A PhD in a relevant scientific discipline, or at least 4 years of industrial experience working with biomolecular NMR

Strong, practical experience in protein‑based NMR spectroscopy

Hands‑on expertise in protein expression and purification, including isotope labelling

Experience setting up, running, and analysing NMR experiments on Bruker systems

A solid understanding of NMR theory as applied to biological macromolecules

The ability to work independently while contributing effectively within project teams

Desirable (But Not Essential) Experience

Understanding of how SPR, NMR, and biophysical techniques are applied in drug discovery

Experience with ligand‑observed NMR methods or reporter assays

Exposure to additional biophysical tools such as SPR, ITC, thermal shift, or MS

Familiarity with fragment‑based or structure‑based drug discovery

Candidates without direct drug discovery biophysics experience will still be considered, provided they have strong protein NMR fundamentals.

Why This Role?

This is an excellent opportunity for a protein‑focused NMR scientist who wants to work in a highly technical, science‑led environment with access to modern instrumentation, challenging biological targets, and collaborative project teams. The role offers real technical ownership and the chance to develop and apply NMR methods that directly influence drug discovery decisions.

For more information, please contact Selby De Klerk at SRG.

SRG are the UK's number one recruitment company specialising in the science, engineering, clinical, pharmaceutical, food/FMCG, renewable, biotech, chemicals and medical devices sectors.

As scientists ourselves, our specialist sector knowledge and passion are second to none. We're committed to providing outstanding temporary, contract and permanent career opportunities of all levels for our candidates.

If this role isn't quite right, feel free to get in touch or visit (url removed) to view our other vacancies.

Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy