Biotechnology Jobs in Oxford

• Oxford
• On-site
• Director · manages people

Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.

• Oxford
• On-site
• £39,424 – £46,476 pa
• Mid-level
• Contract

Carry out research in spatial immunometabolism focused on the germinal centre reaction within the Clarke group at the Kennedy Institute of Rheumatology. The role involves developing new scientific techniques and experimental protocols, testing hypotheses, analysing data, contributing ideas for new projects, and providing guidance to postdocs, technicians and PhD students.

• Oxford
• On-site
• £40,178 – £48,700 pa
• Entry level
• Contract

Conducts research characterising crosslinked proteins and lipids under a Wellcome Trust-funded grant, using proteome and lipidome methods including sample preparation, LCMS and data analysis. Manages project administration, guides junior researchers and students, and contributes to reports, publications and external seminars.

LC-MS · nanoLC-MS

• Oxford
• Hybrid
• Lead
• Permanent

You will apply DMPK expertise within multi-disciplinary project teams to solve drug discovery challenges and deliver high-quality candidate molecules into development. The role sits in a biotech using native mass spectrometry and custom chemistry against membrane proteins and intracellular complexes, working in state-of-the-art laboratories in Oxford.

OdyssION

• London
• Hybrid · 2–3 days in office
• US$187,275 – US$312,125 pa
• Director

Leads the scientific design and execution of interventional clinical studies within Medical Affairs, providing medical governance, safety data review and scientific oversight of protocols and analysis plans. Collaborates with cross-functional teams, investigators and thought leaders, and presents results for publications and regulatory submissions. Hybrid role with two to three days per week in office.

Digital Tools

• Waltham, United States
• Hybrid · 2–3 days in office
• US$187,275 – US$312,125 pa
• Director

Leads the scientific design and execution of interventional clinical studies within Medical Affairs, providing medical governance, safety data review and scientific oversight of protocols and analysis plans. Collaborates with cross-functional teams, investigators and thought leaders, and presents results for publications and regulatory submissions. Hybrid role with two to three days per week in office.

• Abingdon
• On-site
• Entry level
• Permanent · Shift work

Operate pilot plant reactors and ancillary equipment in a GMP-regulated large-scale chemical production environment, running multiple syntheses, some never previously scaled. Duties include routine maintenance and reconfiguration of reaction vessels, environmental monitoring, accurate batch documentation, and shift handovers. The role follows a rotating 12-hour day and night shift pattern averaging 42 hours per week.

Microsoft Office

• Manchester
• £38,448 – £46,970 pa
• Entry level
• Contract

Lead mass spectrometry-based proteomics within a Wellcome Discovery Award consortium studying microbial competition and Type VI Secretion Systems. Design and run DIA proteomics experiments, maintain timsTOF and LC instrumentation, and apply R-based analysis pipelines, publishing findings as lead or co-author.

timsTOF HT · timsTOF Ultra AIP · Liquid Chromatography +1

• Oxford
• On-site
• Senior

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

MSD · LIMS · eLNB +1

• Maidenhead
• Hybrid
• Mid-level
• Temporary

Monitoring investigator sites across the North of England for a routine post-market surveillance study within a dedicated FSP model. Involves on-site and remote monitoring, building relationships with investigators, and ensuring patient safety, data quality and regulatory compliance, with travel to Oxford at least monthly plus on-site onboarding and training.

• Didcot
• On-site
• Lead · manages people

Lead a team of software engineers delivering next-generation Raman spectroscopy software from the Laser Spectroscopy Center of Excellence in Oxford (Harwell). The role owns R&D operations across the software product lifecycle, solving engineering challenges and integrating hardware and software with global partners, using modern architectures such as containerisation, Kubernetes, microservices and cloud deployment.

Kubernetes · Linux · Microsoft

• Oxford
• On-site
• £40,000 pa
• Senior
• Permanent

Develops and optimises LC-MS workflows for low-input and single-cell proteomics and/or metabolomics, supporting researchers across the institute with experiment design, method development, data acquisition and interpretation. Works closely with bioinformatics, scientific computing and AI/ML teams, and helps build SOPs and training material for single-cell MS capability.

LC-MS · Flow Cytometry · Sequencing +5

• Oxford
• On-site
• £40,000 pa
• Entry level
• Permanent

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

OrthoRep

• Durham
• £39,560 – £46,970 pa
• Entry level
• Contract

A postdoctoral position investigating whether bacterial enzymes retain post-mortem functions that promote nutrient recycling. The researcher will combine transcriptomics, metabolomics, genetics and large-scale E. coli mutant collections to identify gene products active after death, working in Professor Martin Cann's lab within an interdisciplinary consortium spanning Durham, Edinburgh, Oxford and Cambridge.

Escherichia coli

• Exeter
• Entry level
• Contract

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.

UK Biobank · All of Us · Our Future Health +4