Biotechnology Jobs in Newcastle

• Newcastle upon Tyne
• £21,805 pa
• Entry level
• Contract

Investigates the molecular mechanisms of liver dysfunction in childhood POLG-related mitochondrial disease, focusing on Alpers-Huttenlocher syndrome. Uses quantitative untargeted proteomics and immunohistochemistry on donated post-mortem liver tissue, and generates hepatic organoids from patient-derived iPSCs for disease modelling and therapeutic screening. Based in the Newcastle Mitochondrial Research Group with a placement at the University of St Andrews.

iPSCs

• Newcastle upon Tyne
• £30,180 pa
• Contract

Support ongoing research in the Murray lab on the mechanism of DNA in bacteria, using standard microbiology techniques, bacterial two-hybrid assays, and AlphaFold3 to predict protein-protein interfaces. The post also provides direct support to a cohort of undergraduate research students, working within a professional technical community under the Biosciences Institute Technical Manager.

AlphaFold3

• Manchester
• £38,448 – £46,970 pa
• Entry level
• Contract

Lead mass spectrometry-based proteomics within a Wellcome Discovery Award consortium studying microbial competition and Type VI Secretion Systems. Design and run DIA proteomics experiments, maintain timsTOF and LC instrumentation, and apply R-based analysis pipelines, publishing findings as lead or co-author.

timsTOF HT · timsTOF Ultra AIP · Liquid Chromatography +1

• Newcastle upon Tyne
• On-site
• Entry level
• Permanent

Graduate-level role in a cancer diagnostics R&D team, generating and evaluating antibodies and detection methods for in vitro diagnostic assays on manual and automated staining systems. Involves laboratory work, literature and competitor reviews, and contributing to product development, verification and validation in a regulated environment, with training in histopathology and immunohistochemistry.

Automated Staining Systems · Manual Staining Systems

• Newcastle upon Tyne
• On-site
• Senior

Leads and coordinates global field action management across Leica Biosystems, including recalls, corrections, removals and Field Safety Corrective Actions. Acts as global process owner and subject matter expert, partnering with Quality, Regulatory, Operations and Commercial teams on investigations, risk assessments and vigilance reporting. Also drives inspection readiness, KPI monitoring and continuous improvement across regions.

EU IVDR · ISO 13485 · FDA +1

• Newcastle upon Tyne
• £48,337 – £68,817 pa
• Senior
• Contract

Lead an independent research programme in transplant immunology, focusing on kidney transplantation injury and new therapies, while collaborating with nine senior investigators and the NIHR Blood and Transplant Research Unit. Contribute 0.2 WTE to undergraduate and postgraduate teaching and PhD supervision within the Translational and Clinical Research Institute.

Transplant Biobank

• Newcastle upon Tyne
• On-site
• Senior

Provides advanced third-level technical support for Digital Pathology products including the Aperio GT Platform, CytoVision and CytoInsight, resolving complex escalations and communicating guidance to field teams. Owns service readiness for change requests and new product development, partnering with R&D, Quality and Product Management to turn findings into documented defects and service improvements.

Aperio GT Platform · Aperio FL · CytoVision +7

• Newcastle upon Tyne
• Hybrid
• Director

Provides medical and clinical leadership for the development of novel diagnostic and companion diagnostic assays and platforms supporting precision medicine. Acts as subject matter expert for R&D projects, clinical studies and regulatory submissions, and supports pharma partnerships and pathology education. Hybrid role based in Newcastle Upon Tyne with 30-40% international travel.

IVD · CDx · Digital Pathology