Jobs in Bristol

Spotlight

Scientist I – Molecular Biology

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

Alloy Therapeutics UK Ltd Cambridge £45,000 – £50,000 pa

On-site Permanent

Spotlight

Senior Computational Chemist, LNP Design

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

CureAge Therapeutics London

Hybrid Permanent Part-time

Director, Regulatory Strategy Lead Europe

Leads EU regulatory strategy for an immunology and cardiovascular portfolio, from early development through registration and lifecycle management. Acts as the regulatory lead for assigned development teams, negotiating with the EMA and other health authorities and building integrated submission plans. Integrates scientific, medical, legal and business perspectives while monitoring European regulatory trends.

Bristol Myers Squibb Uxbridge

Hybrid

Director, Global Clinical Physician Late HOCT - GI Oncology

Serves as the primary medical accountability lead for multiple Phase 1–3 clinical trials in GI oncology, overseeing medical monitoring, safety assessment and benefit/risk analysis within a matrixed Study Delivery Team. Partners with Clinical Scientists on protocol design, site interactions and health authority submissions, while building relationships with principal investigators and thought leaders.

Bristol Myers Squibb Uxbridge

Lead Data and Signal Processing Engineer

Lead the development of a signal-processing pipeline that turns raw optical sensor measurements into reliable analytical results, covering filtering, noise removal, bias compensation and calibration. The hands-on technical leadership role focuses on algorithms rather than product software or UI, working with scientists and engineers in a multidisciplinary team. It starts without line management but offers the chance to build a team as the company grows.

Carbometrics Bristol £60,000 – £70,000 pa

On-site Permanent

Analytical Scientist

Perform routine, non-routine and stability testing on finished pharmaceutical products at a client site, using HPLC, Dissolution, Karl Fischer and UV techniques. The role also covers technology transfers, analytical validation, GMP data review and OOS investigations, working within a managed services team embedded at the client's facility.

Eurofins Liverpool

On-site Permanent

Analytical Chemical Process Development Scientist

Perform method development and proof-of-concept validation on pharmaceutical raw materials, intermediates and drug substances, mainly APIs, using HPLC, GC and MS. Support technology transfers for novel substances, review data for compliance, investigate OOS/OOE results and document work to client procedures. Based on-site at a client facility as a managed PSS scientist, liaising with client representatives and supporting audits and continuous improvement.

Eurofins Liverpool

On-site Permanent