Biotechnology Jobs

• Cambridge
• On-site
• £42,254 – £56,535 pa
• Mid-level · manages people
• Contract

Manage a small sub-team fulfilling genomic data requests, defining cohorts from genomic profiles and delivering datasets to researchers. Work spans LINUX/UNIX, HPC, scripting in Python, R and Bash, Git, and database management, with datasets moving from CSD3 to AWS and a commercial bioinformatics platform. Also contributes to wider Bioinformatics team activities.

AWS · CSD3 · Git

• Oxford
• On-site
• Permanent

Develop and apply computational methods to analyse complex plant genomes, building pipelines for genome assembly, annotation and variant analysis. Work closely with bioinformatics engineers and research scientists to translate biological questions into reproducible workflows and prioritise targets for crop engineering.

• Oxford
• Hybrid
• Senior
• Permanent

Design and develop novel computational algorithms and AI/ML methods for translating metagenomic sequencing data into clinically actionable results, covering taxonomic classification and antimicrobial resistance. Validate and benchmark methods on public and internal datasets, then work with bioinformaticians and software engineers to embed them in scalable, reproducible workflows for an infectious disease diagnostic product.

Oracle Cloud · Long-Read Sequencing

• Cambridge
• £71,200 – £113,200 pa
• Senior · manages people

Leads day-to-day operations of a genomics hub, managing NGS workflows such as RNAseq, ATACseq and single cell genomics, plus SOPs, data management, equipment and budgets. Provides hands-on wet lab guidance and acts as subject matter expert on experimental design while training and supervising technical staff.

• Sheffield
• £32,722 – £37,369 pa
• Senior
• Contract

You will process samples for molecular and genomic analysis, maintain laboratory equipment, and support visiting researchers in a Genomics Laboratory. The role also involves training users new to molecular biology, advising external clients, and contributing to research and development that expands the facility's capabilities.

eDNA

• Norwich
• £21,805 pa
• Entry level
• Contract

A PhD studentship using historical DNA and whole-genome sequencing to study how red squirrel populations in Britain declined, were rescued by translocations, and lost native ancestry. The student will sequence modern and museum specimens, analyse genetic diversity, inbreeding and genetic load over time, and receive training in molecular biology, bioinformatics and population genetics.

• Exeter
• £21,805 pa
• Entry level
• Contract

An interdisciplinary PhD studentship combining computational genomics at Exeter with stem-cell biology and CRISPR editing at Cambridge. The student will analyse whole-genome sequencing data from large multi-ancestry cohorts, integrate genetic signals with epigenetic maps and AI tools like AlphaGenome, and build iPSC-derived visceral and subcutaneous adipocyte models to functionally test prioritised regulatory variants.

AlphaGenome · DNANexus · Flow Cytometry +1

• Norwich
• On-site
• £21,805 pa
• Entry level
• Contract

Investigate why sexually antagonistic genes persist, using Drosophila to identify consistent loci and validate their sex-specific fitness effects via CRISPR-Cas9 allele swaps. Combines bioinformatics, genome engineering and sequencing, with training across evolutionary genetics, statistics and functional genomics at Norwich Research Park.

CRISPR-Cas9 · Long-read Sequencing · Single-cell Transcriptomics

• London
• £51,753 – £53,301 pa
• Contract · Part time

Supports teaching, assessment and curriculum development for an online Genomic Medicine programme, including distance-learning provision and postgraduate education. Supervises student research projects and works with clinical partners to align content with contemporary genomic healthcare practice.

• Exeter
• Entry level
• Contract

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.

UK Biobank · All of Us · Our Future Health +4

• Oxford
• On-site
• £39,424 – £47,779 pa
• Entry level
• Contract

Develop novel statistical and machine learning methods for large-scale genomic, phenotypic and health data, covering areas such as genomic language models, multimodal and federated learning, and multi-ancestry methods. Implement reproducible research software, apply it to biobank-scale datasets, evaluate statistical and predictive performance, publish findings and guide junior researchers.

• Saffron Walden
• Hybrid
• £38,570 – £49,893 pa
• Senior
• Contract

Develop and apply statistical and deep learning methods to cell-free DNA from pregnant women, calling fetal and maternal genotypes from high-coverage sequence data and building methylation-aware biomarkers for pregnancy complications. Work spans methods development, large cohort application and collaboration with international partners in a statistical genomics group.

Python · R · Unix +6

• London
• Senior
• Permanent

Develops and benchmarks machine learning models for DNA sequence, regulatory elements and genetic variation, including variant effect prediction and representation learning. Integrates sequence-derived representations with transcriptomic, epigenomic and perturbational data to uncover disease mechanisms and support target prioritisation, working within the interdisciplinary Rosalind team.

Transformer · DNA Language Models · Genomic Foundation Models +2

• London
• Hybrid
• Lead
• Permanent

Provide scientific leadership across model evaluation and applied use cases, ensuring foundation models stay grounded in drug development and translational research challenges. Act as a senior individual contributor and key scientific partner, mentoring junior colleagues and working with Product and Business Development to turn biology and ML into customer-facing deliverables as the team scales.

• Stevenage
• £74,250 – £202,125 pa
• Lead

Joins the Genomic Technologies group within Translational Sciences, working in an existing Statistical Genetics team. Develops and tests production methods for analysing large-scale human genetic data, integrating genetic association data across omic and phenotypic layers to identify causal genes, drug targets and biomarkers. Collaborates with Data and Predictive Sciences, Biostatistics, AI/ML and disease area teams to influence portfolio decisions.

PySpark · BigQuery · Docker +3