Latest Biotech Research Scientist Jobs

Senior Research Scientist, Mathematical Foundations

This role involves pioneering research at the intersection of mathematics, machine learning, and biology, focusing on developing novel theoretical frameworks for large-scale foundation models trained on unique metagenomic data. The scientist will lead independent research directions, publish at top venues, and translate mathematical insights into AI models that generate novel biological sequences. The position emphasizes first-principles thinking, collaboration, and real-world impact in therapeutic discovery.

Basecamp Research London, United Kingdom
On-site Permanent
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Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects at the intersection of medicinal chemistry and AI, guiding programs from initiation to candidate selection. Collaborate closely with machine learning scientists to refine AI-driven drug design models and drive innovation in synthetic organic chemistry. Play a key role in shaping next-generation therapeutic development through strategic input, CRO management, and intellectual property generation.

Isomorphic Labs Cambridge, United Kingdom

Senior Bioinformatics Scientist

A Senior Bioinformatics Scientist will define data requirements for AI models, design biologically sound datasets and evaluations, and ensure data integrity in training foundational genomic models. The role involves close collaboration with deep learning and engineering teams to validate model performance and biological relevance. Work focuses on sequence analysis, annotation, and evolutionary-scale data interpretation to support therapeutic discovery.

Basecamp Research London, United Kingdom
On-site Permanent

Associate Principal Scientist - In Vivo Pharmacology

Lead and direct in vivo pharmacology studies within multidisciplinary teams to advance preclinical drug discovery programmes targeting kidney diseases such as CKD, AKI, and diabetic nephropathy. Design and interpret translational studies using disease models, support target validation, and guide therapeutic development through biomarker and efficacy analysis. Collaborate with biotech and pharma partners while mentoring scientists and shaping scientific strategy.

Proclinical Nottingham, Nottinghamshire, United Kingdom £50,000 – £500,000 pa

Senior Scientist - ELN & Data Specialist, Global Technical Development

This role involves hands-on administration, configuration, and continuous improvement of an Electronic Lab Notebook (ELN) platform to support R&D and Technical Development laboratories. The scientist will define ELN standards, design workflows and templates, integrate systems, and develop data repositories to enable data-driven decision-making. Collaboration with cross-functional teams is essential to ensure compliance, data integrity, and effective use of the ELN across scientific operations.

Orchard Therapeutics London, United Kingdom
Hybrid Permanent
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Bioanalytical Lead, London

Lead the development and execution of bioanalytical strategies for a diverse portfolio of AI-designed therapeutics, including small molecules, biologics, and ADCs. Design and validate PK, PD, and immunogenicity assays, manage global CROs, and integrate bioanalytical data into AI models to refine drug discovery. Play a key role in IND-enabling studies and cross-functional preclinical development in a hybrid London-based role.

Isomorphic Labs London, United Kingdom
Hybrid Permanent
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Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

This role involves developing, validating, and executing ligand-binding and cell-based assays to support mRNA medicine development. The candidate will generate pharmacodynamic and immunogenicity data in a regulated GcLP environment, manage critical reagent characterization, and contribute to clinical sample testing using Watson LIMS. The position emphasizes scientific rigor, regulatory compliance, and collaboration within a high-performance team advancing novel bioanalytical assays.

Moderna Oxford, United Kingdom
Hybrid Permanent
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Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

Develops and validates ligand-binding and cell-based assays to support clinical programs for mRNA medicines. Performs pharmacodynamic and immunogenicity testing in compliance with GcLP, using platforms like Thermo Watson LIMS. Contributes to assay development, reagent management, and regulatory documentation in a fast-paced, innovative lab environment.

Hybrid Permanent

Head of Neurodegeneration, Translational Medicine

This role involves leading the translational strategy for neurodegenerative disease programs from discovery through early clinical development. The Head of Neurodegeneration will guide global cross-functional teams, design first-in-human and Phase IIa studies, and shape biomarker and patient-relevant endpoint strategies. They will act as a scientific thought leader while engaging with regulatory authorities, KOLs, and internal stakeholders to advance therapeutic innovation in a hybrid work environment.

Novartis London, United Kingdom
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Translational Science Lead

Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.

AstraZeneca Cambridge, United Kingdom

Senior Account Executive

This role involves leading end-to-end enterprise sales cycles to acquire new clients in the pharmaceutical and biotech sectors. The Senior Account Executive will engage with scientific, technical, and executive stakeholders to position Helical’s AI-native biology platform, translating complex technology into tangible value. The position offers a strategic opportunity to shape the commercial strategy of an early-stage company at the intersection of AI and drug discovery.

Helical London, United Kingdom
Hybrid Permanent

Application Engineer

The role involves supporting technical sales and customer relationships for microfluidic systems, handling pre- and post-sales activities including quoting, CRM management, and customer support. The engineer will collaborate with technical teams to meet client requirements and represent the company at trade events. It offers exposure to international projects across diverse sectors such as life sciences and space.

Jackson Hogg Gateshead, Tyne & Wear, United Kingdom £30,000 – £32,000 pa

Automation Engineer - Pharmaceutical Project

This role involves designing, implementing, and commissioning automation systems for a pharmaceutical manufacturing expansion project within a GMP-regulated environment. The engineer will work on PLC, SCADA, DCS, and BMS systems, ensuring compliance with validation, data integrity, and cybersecurity standards while coordinating with vendors and multidisciplinary teams. Key responsibilities include technical oversight, documentation review, and supporting FAT, SAT, and qualification activities.

Eden Brown Middlesbrough, North Yorkshire, DL6 3QB, United Kingdom £70,000 – £80,000 pa
Hybrid Contract Clearance Required

FP&A Manager (Clinical and Project Finance)

The FP&A Manager will lead financial planning and analysis for clinical trials and R&D projects, providing strategic business partnering to scientific and operational teams. This role involves driving financial governance, forecasting, and the automation of reporting processes within a growing biotech environment. The individual will play a key part in scaling financial operations to support OMass’s pipeline in rare diseases and immunology.

OMass Therapeutics Oxford, United Kingdom
Hybrid Permanent

Software Developer - Biology

This role involves building and maintaining scalable software systems for virtual drug discovery, integrating bio foundation models into production pipelines, and developing tools for biological data analysis and visualization. The developer will work closely with ML scientists, backend engineers, and biologists to optimize workflows and ensure reliable, high-performance execution of in-silico experiments. It's a cross-disciplinary position combining computational biology, software engineering, and AI-driven drug discovery.

Helical London, United Kingdom
Hybrid Permanent