Latest Gene Therapy Scientist Jobs

Senior Scientist - ELN & Data Specialist, Global Technical Development

This role involves hands-on administration, configuration, and continuous improvement of an Electronic Lab Notebook (ELN) platform to support R&D and Technical Development laboratories. The scientist will define ELN standards, design workflows and templates, integrate systems, and develop data repositories to enable data-driven decision-making. Collaboration with cross-functional teams is essential to ensure compliance, data integrity, and effective use of the ELN across scientific operations.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Scientist - Translational Research

Support translational research by assisting in normothermic machine perfusion experiments and a range of laboratory techniques including cell culture, flow cytometry, and molecular biology. Contribute to gene therapy development using advanced in vitro models, with training provided and no prior perfusion experience required.

Talentmark Oxford, Oxfordshire, United Kingdom £29,000 – £37,000 pa

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Clinical Trial Case Manager

Manages clinical trial case management activities, ensuring compliance with international and national regulations including GxP and pharmacovigilance standards. Oversees safety reporting, vendor performance, and case processing for serious adverse events, while acting as a key liaison for inspections and audits. Provides training, supports database enhancements, and ensures accurate coding and consistency in safety data analysis.

CSL

Director, Search & Evaluation Early TA Lead (CVR)

Leads strategic sourcing and evaluation of early-stage (preclinical to Phase 1) external innovation opportunities in the Cardiovascular/Renal therapeutic area. Drives due diligence, shapes partnering strategies, and collaborates with Business Development to execute transactions. Embedded in the Therapeutic Area Leadership Team to align external innovation with portfolio planning.

CSL

Research Associate in Functional Genomics

This role involves establishing and running iPSC-derived kidney and ureteric bud organoid models, using CRISPR interference to perturb candidate cis-regulatory elements, and profiling the consequences using advanced techniques like single-nucleus multiomics and CUT&RUN. You will work collaboratively with bioinformaticians and clinicians to generate and test hypotheses, and have opportunities for advanced training and independent research.

Imperial College London London, United Kingdom £50 – £59 pa

Contract

Research Assistant in Cancer Immunology (Maternity Cover)

This role involves conducting wet-lab research on antibody effector functions in hepatocellular carcinoma using preclinical models induced by hydrodynamic gene transfer. The researcher will manage in vivo experiments, analyse data, contribute to publications, and support grant applications within a Cancer Research UK-funded programme. The position is based at the Oxford Centre for Immuno-Oncology and plays a key role in developing novel antibody-based immunotherapies for solid tumours.

University of Oxford Oxford, South East England, United Kingdom £35 – £41 pa

Contract

Laboratory Technician

Process environmental samples through DNA extraction, normalization, and library preparation pipelines using automated systems and manual techniques. Perform QC checks, maintain LIMS records, and support R&D protocol testing in a high-throughput, CL2-compliant lab environment. Contribute to maintaining a safe, organized workspace and enable scalable data generation for AI-driven biological discovery.

Basecamp Research London, United Kingdom

On-site Permanent

Senior Scientist, R&D

Develops and optimizes metagenomic extraction and sequencing workflows for diverse sample types, focusing on low-biomass and inhibitor-rich matrices. Works end-to-end from DNA/RNA extraction to library prep, with emphasis on high molecular weight recovery and virology applications. Collaborates globally to enhance data quality and scalability for AI-driven biological discovery.

Basecamp Research London, United Kingdom

On-site Permanent

Vector Design Lead - Plant Biology Institute

This role leads the design and delivery of transformation-ready vectors and genome editing reagents for crop improvement programs, focusing on molecular construct development for gene editing and transgenic approaches in species like corn and wheat. The position establishes industrial-grade design standards, ensures technical robustness and regulatory alignment, and integrates with high-throughput transformation pipelines. It involves close collaboration with genotyping, automation, and commercial teams to enable scalable, traceable, and auditable vector development from concept to release.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent

Scientist, Cell-Based Screening - Plant Biology Institute

Develop and lead a plant cell-based screening platform to evaluate carbon fixation and photosynthetic efficiency, using suspension cultures and genetic engineering techniques like CRISPR. Identify improved enzyme variants and metabolic pathways, then validate top candidates in whole plants to enhance crop performance. Work within a multidisciplinary team to drive discovery from lab to scalable agricultural solutions, with strong emphasis on IP generation and ethical innovation.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent