Latest Gene Therapy Scientist Jobs

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and regulatory standards. The position emphasizes data integrity, cross-functional collaboration, and integration of emerging technologies, including AI-enabled data analysis, to accelerate clinical development.

Moderna Oxford, United Kingdom

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assay (LBA) bioanalysis within Moderna’s mRNA-LNP therapeutic development programs. The Principal Scientist will oversee regulated assay development, validation, and sample testing, ensuring compliance with GcLP, GLP, and regulatory standards. The position emphasizes cross-functional collaboration, data interpretation, and integration of emerging technologies, including AI-enabled analytics, to support clinical decision-making across the drug development lifecycle.

Moderna

Hybrid Permanent

Clinical Development Medical Director - Neuromuscular

Leads global clinical development programs in neuroscience, with a focus on neuromuscular or related disorders. Provides medical leadership across trial design, regulatory submissions, and safety monitoring, collaborating with cross-functional teams and external stakeholders. Plays a strategic role in advancing innovative therapies through clinical execution and scientific insight.

Novartis London, United Kingdom £83,510 – £155,090 pa

Hybrid Permanent

Clinical Development Medical Director - Neuromuscular

A Clinical Development Medical Director role focused on neuroscience, particularly neuromuscular conditions, with responsibility for shaping global clinical strategies and leading drug development programs. The position involves leading regulatory submissions, overseeing clinical trial execution, interpreting data, and engaging with regulatory authorities and key opinion leaders. Expertise in gene therapy and neurodegenerative disorders is highly valued within a collaborative, international environment.

Novartis £83,510 – £155,090 pa

Hybrid Permanent

Senior Clinical Trial Case Manager

This role involves leading safety data review and pharmacovigilance activities within clinical trials, ensuring compliance with international regulations such as GxP. The individual will mentor team members, manage CAPAs, support regulatory inspections, and contribute to safety reporting and risk management. Key responsibilities include MedDRA coding, safety data analysis, and developing pharmacovigilance procedures to support global regulatory requirements.

CSL

On-site Permanent

Director, Regional Ecosystem Lead (Northern Europe & UK)

This role involves leading CSL's presence in key innovation hubs across Northern Europe and the UK, building strategic relationships with biotech, academia, and investment networks. The Director will source and evaluate opportunities, lead deal teams, and represent CSL at industry events to enhance the company's reputation and deal flow.

CSL United Kingdom

Hybrid Permanent

Research Associate - Specialism in Bioinformatics with Potential Wetlab Experience

This role involves analysing high-throughput sequencing data to investigate RNA regulation in innate immunity, with responsibilities spanning computational analysis of multi-omics datasets and potential wet-lab experimentation. The researcher will apply bioinformatics techniques to study post-transcriptional regulation mediated by the ELAVL1 protein, using methods such as RNA-seq, eCLIP, and SLAM-seq. There is also an opportunity to contribute to experimental design, conduct CRISPR-based assays, and support training within a multidisciplinary team focused on inflammatory disease mechanisms.

University of Sheffield Sheffield, Northern England, United Kingdom £38 – £41 pa

Contract

Protein Scientist

The Protein Scientist will lead protein expression and purification efforts for challenging targets, including membrane proteins and multi-protein complexes, to support structural biology initiatives such as cryo-EM and X-ray crystallography. The role involves developing robust production protocols, characterising protein purity and homogeneity, and collaborating with multidisciplinary teams to advance therapeutic discovery from gene to structure.

Hyper Recruitment Solutions Cambridgeshire, United Kingdom

Hybrid Contract

Associate Director, Clinical Trial Disclosure & Transparency

This role leads global clinical trial disclosure and transparency strategy, ensuring compliance with international regulations such as FDAAA, EU CTR, and MHRA requirements. The individual oversees study registration, results reporting, and layperson summaries, while guiding cross-functional teams and managing vendor performance. They also support redaction of confidential information and drive process improvements across disclosure operations.

CSL United Kingdom

Senior Director, Search & Evaluation Late TA Lead, Immunology

This role involves leading strategic sourcing and evaluation of late-stage external Hematology therapeutic area opportunities, from Phase 2 through marketed drugs. Responsibilities include engaging with Key Opinion Leaders, driving due diligence, and shaping the portfolio through high-impact partnerships.

CSL United States £263,000 – £328,000 pa

Hybrid Permanent

Senior Director, Search & Evaluation Late TA Lead, Immunology

This role involves leading strategic sourcing and evaluation of late-stage external Hematology therapeutic assets, engaging with key opinion leaders, and integrating innovation priorities into portfolio planning. The position requires deep clinical expertise and a proven track record in business development and deal-making.

CSL £263,000 – £328,000 pa

Hybrid Permanent

Senior Director, Search & Evaluation Late TA Lead, Immunology

This role involves leading strategic sourcing and evaluation of late-stage external Hematology therapeutic assets, engaging with key opinion leaders, and integrating innovation into portfolio planning. The position requires deep clinical expertise, a proven track record in deal-making, and strong collaboration with cross-functional teams.

CSL £263,000 – £328,000 pa

Hybrid Permanent

Senior Manager, Clinical Operations - FSP Resource & Vendor Management

This role leads the strategic management of Functional Service Provider (FSP) resources within Clinical Operations, shaping workforce planning, vendor performance, and financial oversight. The individual will develop data-driven resourcing models, act as the primary Clinical Operations liaison to FSP vendors, and ensure alignment with procurement and finance functions. It involves governance, system optimization, and advisory support to clinical leaders, with a focus on cost, quality, and scalability in a global matrix environment.

CSL US$170,000 – US$201,000 pa

Hybrid Permanent

Senior Manager, Clinical Operations - FSP Resource & Vendor Management

This role leads the strategic management of FSP (Functional Service Provider) resources within Clinical Operations, ensuring optimal resourcing, vendor performance, and cost efficiency across clinical trial functions. The individual will develop data-driven workforce plans, manage operational relationships with FSP vendors, and partner with Procurement/Outsourcing Excellence to align resourcing with business needs. The position plays a key advisory role to clinical leaders and drives reporting, financial oversight, and process improvements in a hybrid work environment.

CSL US$170,000 – US$201,000 pa

Hybrid Permanent

Senior Legal Counsel Neuroscience & Gene Therapies, International

This role involves providing strategic legal guidance for neuroscience and gene therapy products across international markets, supporting commercial, medical, and development teams. The Senior Legal Counsel will lead complex agreements, manage global regulatory and compliance risks, and enable innovative therapies through close collaboration with cross-functional and global legal teams.

Novartis London, United Kingdom £92,960 – £172,640 pa

Hybrid Permanent