Biotechnology Jobs

Compound Coordinator (Chemistry Data Generation, Drug Discovery), London

This role involves coordinating compound management and supply across external CROs to support drug discovery data generation efforts. The coordinator will streamline processes, ensure timely chemical procurement, and support internal registration systems. It sits at the intersection of chemistry operations and AI-driven drug design, requiring strong organisational skills and collaboration with both scientific and technical teams.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Country Study Manager (Local Delivery Lead)

This role involves leading the operational planning and delivery of Phase I-IV clinical trials within a specific country or cluster of countries, ensuring compliance with GSK standards, local regulations, and ICH GCP. The manager will coordinate cross-functional teams, oversee study timelines and recruitment targets, manage regulatory submissions, and ensure data integrity and audit readiness. Use of AI-enabled tools and digital solutions is encouraged to enhance efficiency and decision-making in clinical trial operations.

GSK United Kingdom

Associate Director of Clinical Sciences

Lead clinical sciences strategy and execution for global oncology studies, with responsibility for end-to-end protocol development, clinical data review, and cross-functional collaboration. Focus on immuno-oncology with strong emphasis on regulatory compliance, patient safety, and scientific leadership across clinical development phases. Work within a matrix environment to guide study design, interpretation, and regulatory submissions.

GSK Stevenage, United Kingdom

Head of DMPK

Leads DMPK strategy to advance drug programs from discovery to clinical development, integrating predictive modeling and high-throughput data. Builds and guides a scientific team while collaborating across functions and external partners to de-risk and accelerate therapeutic pipelines with a tech-forward approach.

Recursion London, United Kingdom £166,500 – £208,100 pa

Hybrid Permanent

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based therapeutic development. The scientist will lead assay development for clinical programmes using platforms like ELISA, MSD, and cell-based methods, ensuring regulatory compliance and robust data generation. The position emphasizes collaboration across multidisciplinary teams and integration of digital tools and AI to advance Moderna's pipeline.

Moderna Oxford, United Kingdom

On-site Contract

Head of DMPK

Leads the development and execution of DMPK strategy across drug discovery and development programs, integrating predictive ADME modeling and high-throughput experimental data. Bridges computational and experimental teams to accelerate small molecule and emerging modality programs from hit identification through IND-enabling studies. Builds and mentors a high-performing DMPK team within a cross-functional, tech-driven drug discovery environment.

Recursion United Kingdom US$284,900 – US$400,950 pa

Hybrid Permanent

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based clinical development programmes. The scientist will lead assay development—including ADA, nAb, PK, and PD assays—using platforms like ELISA, MSD, and cell culture, while ensuring regulatory compliance and contributing to Moderna's expanding capabilities in Harwell. The position emphasizes collaboration across multidisciplinary teams and integration of digital and AI-enabled tools to enhance data interpretation and decision-making.

Moderna

On-site

Translational Medicine Expert – Dermatology, Associate Director

This role involves providing medical and scientific leadership in translational medicine for dermatology programs, spanning early to late-stage drug development. The expert will design and implement strategies for clinical pharmacology, biomarker development, and regulatory submissions, while leading cross-functional teams and supporting in-licensing opportunities. Work includes oversight of clinical studies, publication strategy, and engagement with regulatory and external stakeholders.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Associate Director of Clinical Sciences

This role involves leading clinical sciences activities in global oncology studies, with responsibility for end-to-end protocol development, clinical data review, and cross-functional collaboration. The individual will shape study design, interpret results, and ensure regulatory compliance across phases of development, with a focus on immuno-oncology. The position requires scientific leadership, engagement with external experts, and contribution to regulatory submissions and clinical strategy.

GSK United States

Associate Director of Clinical Sciences

This role involves leading clinical sciences activities within global oncology R&D, focusing on study design, protocol development, and clinical data review across the development lifecycle. The individual will act as a subject matter expert, ensuring scientific rigor and regulatory compliance while collaborating with cross-functional teams and external partners. A key focus is on immuno-oncology, with responsibilities spanning from early-phase to late-stage clinical development.

GSK