Biotechnology Jobs

• Durham Blackwell Street
• Hybrid
• US$188,100 – US$313,500 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within a matrixed Clinical Pharmacology Modelling and Simulation group working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Zug, Switzerland
• Hybrid · 2–3 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within a clinical programme team, leading medical monitoring, safety oversight and data interpretation for GI oncology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement. Requires an on-site presence 2-3 days a week across UK, Swiss or US sites.

AI-enabled Insights

• United Kingdom
• Remote
• Senior

Clinical Research Associate role within PPD's Functional Service Provider division, dedicated to a client and embedded in multi-national project teams. You perform and coordinate all aspects of clinical monitoring, conducting monitoring activities independently across challenging projects. Requires ICH-GCP, EU and FDA knowledge, with award-winning training provided.

• Swindon
• Lead · manages people

Leads a team of scientific officers performing GMP QC Chemistry analysis of incoming goods, in-process, intermediate, stability and finished product samples. Acts as first escalation point for technical, compliance and personnel issues, manages batch release, stability studies, documentation and audits, and deputises for the QC Manager. Requires extensive instrumental and traditional analytical experience plus 2+ years of team leadership.

• London
• Lead

Serves as subject matter expert in COA endpoint strategy, instrument development and regulatory strategy, advising pharma and biotech sponsors and representing the company as an external scientific thought leader. Leads qualitative research supporting content validity, oversees internal project teams, mentors consultants and supports business development through proposals and client presentations.

• Abingdon
• Lead
• Permanent

Acts as the single front door between Evotec's Drug Discovery Platforms and the global In Silico & AI organisation, owning demand, relationships and the in silico roadmap. Translates platform science needs across DMPK, ADME/Tox, predictive safety, screening and omics into prioritised AI requirements, then orchestrates delivery across capability units. Carries a commercial mandate, contributing to client proposals, pricing and evidencing value such as margin uplift and cycle time.

• Oxford
• On-site
• Entry level
• Temporary

Operate manufacturing equipment for mRNA vaccine production under cGMP and SOPs, maintaining documentation, gowning and housekeeping standards. Partner with Quality Assurance on batch disposition, lead root cause analysis and CAPA for deviations, and troubleshoot equipment and digital system issues. Work 100% onsite with digital and Generative AI-enabled manufacturing technologies.

Generative AI

• London
• Senior

Leads complex global and multi-regional clinical trials from start-up through close-out, with accountability for quality, timelines, budgets, regulatory compliance and sponsor objectives. Acts as primary strategic partner to sponsors and directs cross-functional teams across regions, with a focus on renal, obesity and MASH studies.

• London
• Hybrid
• Director · manages people

Leads the development and execution of international regulatory strategy across European and Rest of World markets, from first-in-human through post-marketing. Represents Global Regulatory Affairs on core development teams, manages project plans and resources, and advises senior management. Also a people manager within the International GRA leadership team, driving process improvement and regulatory policy engagement.

EMA

• Oxford
• Hybrid · 3–4 days in office
• Senior
• Permanent

Develops, validates and runs ligand-binding and cell-based bioanalytical assays generating pharmacodynamic and immunogenicity data for clinical mRNA programmes. Works in a GcLP-regulated lab using Thermo Watson LIMS and electronic notebooks, handling clinical samples, critical reagents, SOPs and validation reports while partnering with Clinical Operations and Sample Management.

Thermo Watson LIMS · Watson LIMS · LabVantage eLBN +1

• Haywards Heath
• Hybrid · 3 days in office
• Director · manages people

Leads a global team of development and regulatory project managers overseeing complex R&D programs across a therapeutic area, including new product development and lifecycle management. Acts as strategic partner to TA and R&D leadership, driving portfolio planning, agile delivery, risk removal and cross-functional alignment as part of the Portfolio & Operations Excellence leadership team.

Microsoft Project · Planview · Smartsheet +1

• Maidenhead
• Lead · manages people

Provides medical and scientific expertise on clinical safety across the full product lifecycle, with emphasis on evaluating safety data during clinical development and post-approval. Chairs the Safety Management Team, oversees signal detection, aggregate reports (DSURs, PSURs, RMPs) and regulatory responses, and sets safety strategy for global cross-functional development and post-marketing teams.

DSUR · PSUR · RMP +2

• London
• Hybrid
• £56,511 – £104,949 pa
• Mid-level

Lead the development and maintenance of global labelling documents for neuroscience medicines, translating clinical and safety data into compliant product information. Facilitate cross-functional discussions, support Health Authority responses, and ensure timely implementation of labelling changes across global and major markets.

• London
• Hybrid
• £63,917 – £118,703 pa
• Director

Acts as a QA liaison between clinical trial teams and third parties, providing expert support through due diligence, qualification, governance and ongoing monitoring. Focuses on technology-enabled vendors such as digital health tools, medical devices and AI, covering risk assessment, audit support, inspection readiness and escalation of quality issues.

DHT · SaMD · SaaS +1

• Leeds
• On-site
• Senior

Lead early-phase clinical trials as Principal Investigator or Project Physician, taking studies from start-up through closeout and the Clinical Study Report. Work across first-in-human studies, multiple therapeutic areas and an NHS Trust collaboration, with on-call cover and mentoring of less experienced physicians.

MHRA · cGMP · NHS Trust