Latest Drug Discovery Jobs

Bioanalytical Lead, London

Lead the development and execution of bioanalytical strategies for a diverse portfolio of AI-designed therapeutics, including small molecules, biologics, and ADCs. Design and validate PK, PD, and immunogenicity assays, manage global CROs, and integrate bioanalytical data into AI models to refine drug discovery. Play a key role in IND-enabling studies and cross-functional preclinical development in a hybrid London-based role.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Senior Medical Director, Oncology Clinical Development - Lung

This role involves leading clinical development for oncology, specifically in lung cancer, by providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety monitoring, contribute to regulatory interactions, and mentor junior medical staff. The position requires deep expertise in oncology clinical trials and close collaboration with cross-functional teams and external experts.

GSK

Hybrid Permanent

Medical Director Clinical Development- Aging

Lead clinical development for aging-related programs within GSK’s Respiratory, Immunology & Inflammation Research Unit. Provide clinical and scientific leadership across translational and clinical studies, design development plans, and guide regulatory strategy. Work cross-functionally to advance innovative medicines targeting underlying organ dysfunction and unmet medical needs in aging.

GSK Stevenage, United Kingdom US$189,750 – US$316,250 pa

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays (LBA) in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and GCP standards. The position plays a key role in clinical development by generating high-quality data to inform regulatory submissions and advance innovative medicines, with opportunities to engage in AI-enabled and digital analytical approaches.

Moderna

Hybrid Permanent

Global Program Safety Lead - CRM

This role involves leading the end-to-end safety strategy for priority pharmaceutical programs in the Cardio Renal Metabolism (CRM) therapeutic area, from development through lifecycle management. The individual will serve as the scientific safety leader, driving safety governance, benefit-risk assessments, and regulatory interactions, while mentoring teams and embedding safety insights across global functions. It requires deep expertise in pharmacovigilance, cross-functional leadership, and clear communication of complex safety data.

Novartis London, United Kingdom £83,510 – £155,090 pa

Clinical Development Director - Renal

The Clinical Development Director leads and supports clinical development activities within a global program, focusing on strategy, trial execution, data analysis, and regulatory documentation. This role involves close collaboration with cross-functional teams, ensuring scientific rigor and data quality across phases I–IV trials, particularly in late-phase development. The position requires strong scientific expertise, leadership in clinical operations, and active participation in safety and regulatory initiatives.

Novartis London, United Kingdom

Hybrid Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

This role involves leading clinical development for internal medicine assets within Pfizer's Research & Development division, with a focus on obesity-related therapeutics. The Global Development Lead serves as the primary clinical accountability point, designing and executing global clinical development plans, regulatory submissions, and cross-functional team leadership. The position requires deep expertise in endocrinology or chronic weight management and extensive experience in Phase 1-3 clinical trials, translational medicine, and regulatory strategy across global markets.

Pfizer United States £214,900 – £358,100 pa

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (non-MD)

This role leads clinical development for assigned assets in Internal Medicine within Pfizer's R&D division, with accountability for designing and executing global clinical development plans. The individual will guide cross-functional teams through trial design, regulatory submissions, and lifecycle management, while serving as a therapeutic expert and strategic partner across internal and external stakeholders. Emphasis is placed on innovation, patient engagement, and compliance with global regulatory standards.

Pfizer £214,900 – £358,100 pa

On-site Permanent

(Fixed Term) Manufacturing Associate I

Operate and maintain mRNA vaccine production equipment in compliance with cGMP and safety standards, executing manufacturing processes, troubleshooting equipment and digital systems, and supporting quality documentation and continuous improvement initiatives. Work within a cross-functional team to ensure timely batch release and operational excellence in a fast-paced, highly regulated environment.

Moderna Oxford, United Kingdom

On-site Temporary