Biotechnology Jobs

• USA - Pennsylvania - Upper Providence
• US$188,100 – US$313,500 pa
• Director

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic mathematical models of disease and drug action to inform trial design and MIDD strategy. Collaborates with biologists, clinicians, pharmacometricians and AI/ML teams, and represents the function on internal advisory boards.

• London
• Hybrid
• US$188,100 – US$313,500 pa
• Director
• Permanent

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and AI/ML specialists. The role sits in a newly formed centre of excellence and involves representing QSP on internal advisory boards.

• Reading
• Senior

Monitors clinical trial sites across the UK, performing selection, initiation, monitoring and close-out visits in line with GCP and sponsor requirements. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains TMF/ISF documentation. Dedicated to a single sponsor within IQVIA's cFSP model.

Microsoft Word · Microsoft Excel · Microsoft PowerPoint +2

• Reading
• Mid-level

Site monitoring role covering selection, initiation, monitoring and close-out visits in line with GCP and ICH guidelines, plus recruitment tracking, protocol training and TMF/ISF documentation. Dedicated to a single sponsor within IQVIA's cFSP model, with access to large data pools to improve site selection and efficiency.

• Exeter
• Entry level
• Contract

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.

UK Biobank · All of Us · Our Future Health +4

• Exeter
• Entry level
• Contract

Computational PhD project using cell-free DNA sequencing to infer placental gene activity and dissect how genetic variants linked to adverse pregnancy outcomes affect placental function. The student develops tools to map nucleosomal footprints, integrates them with single-cell RNA-seq markers and GWAS summary statistics, and may generate new plasma data.

scRNA-seq · cfDNA Sequencing · GWAS

• Oxford
• On-site
• Senior

Provides hands-on MS&T engineering expertise across drug substance manufacturing and label, packaging and final-storage operations at the Harwell site. Leads technology transfer, process start-up, validation, continued process verification and troubleshooting, authoring protocols and reports as an individual contributor. Works cross-functionally with Manufacturing, Quality and Supply Chain, with on-call or shift coverage as required.

SAP · VEEVA · DeltaV +4

• London
• Senior
• Permanent

Builds generative and predictive models of cellular behaviour from high-content imaging, curating cell painting and brightfield datasets and designing evaluation that separates biological signal from technical artefact. Partners closely with ML scientists and wet lab assay teams, linking imaging readouts to single-cell and perturbation data in a matrixed TechBio environment.

NumPy · pandas · Polars +6

• London
• On-site
• Senior
• Permanent

Processes and quality-controls paired single-cell RNA-seq and scATAC-seq data at scale, building Nextflow pipelines for custom combinatorial indexing chemistries and integrating multimodal datasets for GPU-accelerated model training. Partners with wet lab scientists and ML modellers to design evaluation frameworks and biological benchmarks, bridging experimental and computational teams in a matrixed TechBio environment.

STARsolo · Alevin-fry · Chromap +5

• Oxford
• On-site
• Mid-level · manages people
• Permanent

Lead the governance, lifecycle management and regulatory compliance of physical assets across a growing scientific and engineering campus. Establish and improve an ISO 55000-aligned Asset Management System, driving predictive and condition-based maintenance, whole-life cost modelling and risk-based investment planning. Manages a team and specialist suppliers; explicitly not a facilities or property operations role.

• London
• Hybrid
• Entry level
• Permanent

Early-career scientist role in a Life Sciences team, generating therapeutic hypotheses by mining in-house genomic data with statistical methods to identify and triage drug targets. Also develops and optimises polygenic risk score tools for patient stratification, working with omic data using statistical and AI/ML approaches and communicating findings to internal and external stakeholders.

Git · GitHub · WDL +4

• Guildford
• £38,448 – £46,970 pa
• Entry level
• Contract

Postdoctoral role applying informatics, data science, machine learning and AI to animal health and welfare, within the vHive and Health and Biomedical Informatics Group. Involves in-silico drug repurposing, biomarker discovery from proteomics and transcriptomics, knowledge representation and stakeholder data analysis, in collaboration with industry partner Zoetis and other institutions.

R · Python

• Oxford
• On-site
• Junior
• Permanent

Hands-on bench role executing microbial culture, identification, biobanking and broth microdilution antimicrobial susceptibility testing under BSL-2 conditions, compliant with EUCAST/CLSI guidelines. Works within a highly automated reference laboratory integrating robotics and data systems, with scope to help design and optimise high-throughput workflows alongside microbiologists, genomics scientists and automation engineers.

MALDI-TOF · Oracle · Long-Read Sequencing +1

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Experienced medicinal chemists lead portfolio drug discovery projects from initiation to clinical candidate selection, working as Project Lead or Medicinal Chemistry Lead. They partner closely with ML scientists to refine the AI drug design platform, manage CRO resources, and may line-manage teams of 2-4 chemists.

AlphaFold

• Cambridge, United States
• Hybrid · 3 days in office
• Lead

Lead DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments while integrating DMPK, PD and toxicology data for dose and safety predictions. Work closely with AI/ML platform teams to optimise computational ADME models and author regulatory sections, in a hybrid Cambridge, MA role.

Python · R