490 jobs for “Clinical Data Manager - Early Phase”
Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. Hybrid role with at least two days per week on-site.
AI
Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for genitourinary cancer studies. Partners with the Senior Scientist and cross-functional Clinical Matrix Team on protocol development, investigator engagement and regulatory interactions, with hybrid working of at least two days on-site per week.
AI
Lead and develop a team of Central Monitors, shaping central and site monitoring strategies across a global development portfolio. Oversee trial-data surveillance, risk reviews and signal detection using Central Monitoring technology, translating complex risk signals into actionable insights for Clinical Trial Teams. Partners with clinical, data and risk-surveillance teams to strengthen risk-based monitoring and Risk-Based Quality Management.
Artificial Intelligence
Parexel
Senior Statistical Programmer supporting clinical trials within Parexel's FSP team, producing and QCing SDTM and ADaM datasets, tables, figures and listings using SAS. The role can act as Statistical Programming Lead, coordinating global teams, timelines and budgets while liaising with sponsors and Biostatistics and Data Management leads. It also involves mentoring staff and ensuring compliance with ICH-GCP and CDISC standards.
SAS
Parexel
Senior Statistical Programmer role focused on R programming for clinical trial analysis and reporting, producing and QCing SDTM/ADaM datasets, tables, figures and listings. The position can act as Statistical Programming Lead, coordinating global teams, managing timelines and budgets, and liaising with sponsors and biostatistics. Dedicated to a single sponsor within an FSP model across UK, Poland, Serbia and Hungary.
R · SDTM · ADaM +1
Site-facing role managing Phase I–IV clinical trial sites, acting as the primary contact between the sponsor and sites. Responsibilities include site initiation visits, training, on-site and remote monitoring, risk assessment and mitigation, and closeout activities, working closely with cross-functional teams to ensure data integrity and compliance.
IQVIA
Supports clinical trials by designing, setting up and maintaining Interactive Response Technology (IRT) solutions, translating supply requirements into system specifications. Contributes to risk assessments, user acceptance testing and validation documentation, and advises study teams on IRT processes. Works with cross-functional global stakeholders on study startup, amendments and continuous improvement.
IRT · RTSM · IVRS +1
IQVIA
Monitors clinical trial sites across the UK, handling selection, initiation, monitoring and close-out visits in line with GCP and ICH guidelines. Manages multiple protocols, drives subject recruitment, tracks regulatory submissions and CRF data, and maintains Trial Master File documentation. Based in Reading with regular travel to investigative sites.
Gilead Sciences
Leads clinical development strategy for multiple myeloma cell therapy programs, overseeing trial design, conduct, reporting and regulatory submissions. Represents products in governance committees, provides medical monitoring, and manages a team of direct reports while building external thought-leader relationships.
Workday
Bristol Myers Squibb
Serves as primary medical accountability for Phase 1–3 clinical trials in neuroscience, leading medical monitoring, safety assessment and benefit/risk analysis within a matrixed study delivery team. Partners with clinical scientists on protocol design, site interactions and health authority submissions, and builds relationships with principal investigators and thought leaders.
Nexus Life Sciences
Leads a Clinical Method Development and Validation team, overseeing bioanalytical method delivery for a New Product Development programme. Provides technical leadership in a GLP-compliant lab, acting as expert in extraction techniques and optimising HPLC, UPLC and LCMSMS systems while mentoring the team.
HPLC · UPLC · LCMSMS +1
Hudson Shribman
This role involves leading in-vitro toxicology studies within a regulated preclinical environment, focusing on assay development and execution for product safety assessment. The scientist will apply advanced cell-based methods including Neutral Red, Ames, and micronucleus assays, interpret complex biological data, and support regulatory submissions. Collaboration with internal teams and external partners is key, alongside method validation and scientific reporting in a quality-assured laboratory setting.
Fortrea
Lead and manage clinical trial sites across a diverse portfolio spanning oncology, neuroscience, cell & gene and CAR-T therapies. The role emphasises patient safety, data integrity and building trusted relationships with investigators, with autonomy and support for complex, innovative study designs.
Fortrea
Monitors clinical trial sites across a diverse portfolio spanning oncology, neuroscience, general medicine, cell & gene and CAR-T therapy. Leads site management, builds relationships with investigators and study teams, and safeguards patient safety and data integrity on complex, first-in-class studies. Distinct for its breadth across therapeutic areas and advanced therapy exposure rather than a narrow single-indication focus.
Moderna · 1001–5000 people · Late stage
Designs and delivers immunogenicity and bioanalytical strategies for regulated clinical programmes, developing ADA, nAb, PK and PD assays using ELISA, MSD and cell culture. Works with multidisciplinary teams to validate assays, manage reagents and SOPs, and integrate digital and AI-enabled tools. Site-based at Harwell within a growing mRNA-focused team.
ELISA · MSD · LIMS +2
