Jobs in London

Associate Director, Statistical Programming

Lead a global team of statistical programmers, driving standardization, innovation, and quality in clinical trial data analysis. Develop programming strategies using modern tools like R, Git, and AI-enabled technologies, ensuring audit-ready deliverables and alignment with biostatistics and data management. Provide technical leadership and influence global drug development strategy across phases I–IV studies.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Senior Clinical Development Medical Director

This role involves leading clinical strategy and execution for cardiovascular/stroke medicine programs, with responsibility for trial design, regulatory documentation, and cross-functional collaboration. The Senior Clinical Development Medical Director will guide global teams, interpret complex clinical data, and contribute to safety and development decisions across the drug lifecycle. Expertise in anticoagulation and outcome trials is key, along with strong leadership in a matrix environment.

Novartis London, United Kingdom

Director, Biostatistics

This role involves leading statistical strategy for gene therapy clinical development programs, with responsibilities spanning study design, regulatory engagement, and analysis oversight. The Director will ensure scientific and regulatory rigor in clinical trials, manage vendor performance, and contribute to submissions and publications. It is a hands-on leadership position within a cross-functional team environment.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Senior Medical Director, Oncology Clinical Development - Lung

This role involves leading clinical development for oncology, specifically in lung cancer, by providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety monitoring, contribute to regulatory interactions, and mentor junior medical staff. The position requires deep expertise in oncology clinical trials and close collaboration with cross-functional teams and external experts.

GSK

Hybrid Permanent

Senior Computational Biologist – Early Discovery Immunology

A Senior Computational Biologist will drive target discovery in immunology and inflammatory diseases by integrating multi-omics data (phenomics, transcriptomics, genomics, proteomics) to nominate and validate novel therapeutic targets. The role involves developing computational methods, collaborating with cross-functional teams, and translating complex analyses into actionable drug discovery programs using Recursion’s AI-driven platform.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Senior Computational Biologist - Early Discovery Oncology

Drive target discovery and validation in precision oncology by integrating multimodal biological data (phenomics, transcriptomics, genomics, proteomics) to identify novel therapeutic targets. Collaborate with cross-functional teams to develop scalable computational methods and build compelling data packages that advance drug programs. Develop criteria for target nomination and support early translational strategies using AI-powered platforms.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Clinical Development Medical Director - Neuromuscular

A Clinical Development Medical Director role focused on neuroscience, particularly neuromuscular conditions, with responsibility for shaping global clinical strategies and leading drug development programs. The position involves leading regulatory submissions, overseeing clinical trial execution, interpreting data, and engaging with regulatory authorities and key opinion leaders. Expertise in gene therapy and neurodegenerative disorders is highly valued within a collaborative, international environment.

Novartis £83,510 – £155,090 pa

Hybrid Permanent

Clinical Development Medical Director - Neuromuscular

Leads global clinical development programs in neuroscience, with a focus on neuromuscular or related disorders. Provides medical and scientific leadership across trial design, regulatory submissions, and data interpretation. Engages with regulatory bodies and key opinion leaders to shape clinical strategy and advance innovative therapies.

Novartis Ardross, Alba / Scotland, IV17 0YF, United Kingdom £83,510 – £155,090 pa

Hybrid Permanent

Clinical Development Medical Director - Neuromuscular

Leads global clinical development programs in neuroscience, with a focus on neuromuscular or related disorders. Provides medical and scientific leadership across trial design, regulatory submissions, data interpretation, and external engagement. Works cross-functionally to drive innovative therapies from concept to approval, with emphasis on gene therapy and complex clinical data.

Novartis Ireland €90,300 – €167,700 pa

Hybrid Permanent

Clinical Data Strategy, Manager

This role involves leading clinical data strategy planning and execution across Translational Medicine programs, with a focus on designing fit-for-purpose data collection approaches and supporting robust decision-making. The individual will develop Data Strategy Plans, guide trial teams on data oversight, and leverage internal and external data to inform trial design—particularly in Neuroscience. The position requires deep expertise in clinical assessments, data integrity, and cross-functional collaboration in a global, fast-paced environment.

Novartis London, United Kingdom £49,140 – £91,260 pa

Hybrid Permanent

Medical Safety Lead - CRM

The role involves monitoring clinical safety data, conducting medical assessments of adverse events, and identifying safety signals using both individual and aggregate data. The Medical Safety Lead will apply AI-enabled tools to enhance pharmacovigilance processes and provide critical medical input into regulatory submissions and safety documentation. Collaboration with global cross-functional teams is central to integrating safety insights across drug development programs.

Novartis London, United Kingdom £67,900 – £126,100 pa

Associate Director, Regulatory Diagnostics

This role involves designing and delivering global regulatory strategies for precision diagnostics, including companion diagnostics and in vitro devices, within drug development programs. The individual will lead regulatory submissions across the lifecycle, engage with health authorities, and ensure compliance with global regulations. Collaboration with cross-functional teams and external partners is central to advancing regulatory plans for innovative diagnostics in a hybrid working environment.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Global Medical Affairs Director, Immunology

Lead the development and execution of global medical strategies for immunology products across their lifecycle, from development to market. Drive evidence generation through real-world studies, registries, and investigator-initiated trials while engaging key scientific experts and patient groups. Provide medical leadership at major congresses and advisory boards, ensuring compliance and strategic input into regulatory, access, and launch planning.

Novartis London, United Kingdom £93,870 – £174,330 pa