Biotechnology Jobs

• Oxford
• On-site
• Senior
• Permanent

Lead the development of a plant cell-based screening platform to evaluate carbon fixation, using quantitative methods and CRISPR-based genome editing in suspension cultures. Apply iterative design-build-test-learn cycles to identify improved photosynthesis enzyme variants and engineered pathways, advancing promising candidates into whole plants. Contribute to IP generation and collaborate across multidisciplinary teams.

CRISPR

• Oxford
• Hybrid
• Mid-level
• Permanent

Research Scientist role in the Molecular Simulations and Design team, combining generative models, physical simulation and experimental data to accelerate biomolecule design, initially enzymes. Involves developing methods such as Boltzmann samplers, long-timestep molecular dynamics, machine-learned interatomic potentials and flow matching/diffusion, with full-stack work from pre-training to design-build-test loops.

• Waltham, United States
• Hybrid · 2–3 days in office
• US$187,275 – US$312,125 pa
• Director

Leads the scientific design and execution of interventional clinical studies within Medical Affairs, providing medical governance, safety data review and scientific oversight of protocols and analysis plans. Collaborates with cross-functional teams, investigators and thought leaders, and presents results for publications and regulatory submissions. Hybrid role with two to three days per week in office.

• Macclesfield
• Permanent

Provide analytical support for drug substance manufacturing and method development, running project analysis, forced degradation studies and proof-of-concept validation. Author and review Analytical Testing Plans, method protocols and validation protocols, using HPLC and GC within a GMP-regulated lab. Work independently and in a multidisciplinary team, communicating findings to internal and external stakeholders.

HPLC · GC · NMR +4

• USA - Pennsylvania - Upper Providence
• Hybrid · 2–3 days in office
• US$187,275 – US$312,125 pa
• Director

Leads the scientific design and execution of interventional clinical studies within Medical Affairs, providing medical governance, safety oversight and scientific interpretation of protocols and analysis plans. Collaborates with cross-functional teams, investigators and regulators, and presents results for publications and submissions. Hybrid role with two to three days per week in office.

• Oxford
• Hybrid
• Lead
• Permanent

You will apply DMPK expertise within multi-disciplinary project teams to solve drug discovery challenges and deliver high-quality candidate molecules into development. The role sits in a biotech using native mass spectrometry and custom chemistry against membrane proteins and intracellular complexes, working in state-of-the-art laboratories in Oxford.

OdyssION

• Welwyn
• Hybrid
• Director

Provides safety science and pharmacovigilance support across the Roche portfolio, covering signal detection, benefit-risk assessment, ICSR case management and aggregate reporting such as DSUR and PBRER. The role also involves preparing CCDS, labelling, RMP and REMS documents and shaping drug safety input into clinical development strategy. Level is set by experience, working with a global team from the Welwyn office.

DSUR · PBRER · CCDS +3

• London
• On-site
• Senior
• Permanent

Lead research on the capabilities and risks of biological AI systems, designing evaluations, red-teaming studies and threat models, and developing safeguards across training, model behaviour and access. Work within the frontier model team with access to proprietary genomic data and biological expertise, shaping research priorities and publishing where appropriate.

EDEN · BaseData

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Lead in vitro and cellular pharmacology strategy for small-molecule drug design programs, defining screening cascades and guiding biophysical, biochemical and cell-based assays from hit identification to candidate selection. Bridge computational AI/ML predictions with laboratory validation, managing CRO partnerships and collaborating with chemistry, structural biology and translational teams.

SPR · ITC · CRO

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Designs and implements translational strategies for small molecule oncology and immunology programs, from early discovery through candidate selection and clinical phase. Oversees CRO activities, PK/PD and safety assessments, and biomarker strategies, bridging computational predictions with laboratory validation. Some roles include managing 2-3 in vivo pharmacologists.

Machine Learning · AlphaFold

• Madrid, Spain
• Hybrid
• Senior

Builds, trains, deploys and maintains AI/ML models and automation tools for supply chain master data within Pfizer's Supply Planning Data Intelligence group. Work spans optimization algorithms, predictive models, generative AI/NLP, and autonomous data agents integrated with planning systems like Kinaxis, owning solutions from development through production handover.

scikit-learn · pandas · TensorFlow +7

• United Kingdom
• Remote

Serves as a trusted technical advisor to customers, delivering pre- and post-sales support through product demonstrations, hands-on training, troubleshooting and technical consultation on high-content imaging and screening platforms. Works closely with sales and cross-functional teams, developing and optimising fluorescence-based cell assays and quantitative image analysis. Requires frequent travel across the UK and Ireland, with occasional international trips.

Microsoft Office

• Oxford
• Remote

Provide post-installation applications training and ongoing scientific support for customers using the Nanoimager microscopy platform. Troubleshoot workflow, sample and acquisition issues alongside Service and Product teams, drive adoption and contribute to renewals, and develop reusable training and knowledge-base materials. Involves 25% travel across the UK and Europe.

Nanoimager

• Oxford
• On-site
• £39,424 – £43,984 pa
• Entry level
• Contract

Carries out laboratory research on synthetic genome DNA assembly, generating constructs and testing new approaches using recombinant DNA methylases. Involves molecular cloning, long DNA molecule extraction, bacterial culture and recombinant protein production and purification, with scope for some bioinformatic analysis. Based in a well-equipped Oxford lab, collaborating on translation of synthetic chloroplast genomes into crop plants such as potato and wheat.

DNA Methylases

• Addlestone
• On-site
• £47,557 – £52,010 pa
• Senior · manages people
• Permanent

Lead a UKRI-funded Next Generation Veterinary Vaccines programme, investigating influenza, coronaviruses and zoonotic Disease X threats. Work across multidisciplinary teams using in vitro and in vivo approaches to design and optimise plug-and-play vaccine platforms, assessing immunogenicity, efficacy and antigenic variation. Includes line management, project coordination and work in SAPO4/ACDP3 containment facilities.

SAPO4 · ACDP3