Biotechnology Jobs

• London
• Hybrid · 3 days in office
• Senior · manages people

Lead computational chemistry strategy across drug discovery programs, applying AI-first approaches to hit finding, molecular design and lead optimisation. Work with ML scientists to embed generative models into cheminformatics workflows, with some roles managing 2-3 computational chemists.

REINVENT · AlphaFold · Large Language Models

• London
• Hybrid · 3 days in office
• Lead · manages people

Lead a team of biologists in the Exploratory Sciences group, owning in vitro pharmacology strategy for novel modalities such as TPD, molecular glues and peptides. Design screening cascades and quantitative assays, manage CRO studies, and champion LLM agentic workflows and in silico hypothesis building alongside ML and engineering colleagues.

SPR · GCI · nanoDSF +5

• Oxford
• On-site
• Entry level
• Permanent

Postdoctoral role in the Zuercher Lab at the Generative Biology Institute, working on genome synthesis and genetic isolation. Involves designing and troubleshooting experiments, analysing complex datasets with computational and statistical tools, publishing papers, and mentoring junior researchers. Based at Oxford Science Park in a new bespoke facility.

E. coli

• Oxford
• On-site
• Entry level

Postdoctoral researchers join an interdisciplinary team fabricating three-dimensional living, synthetic and hybrid tissues for disease modelling, therapeutic testing and organ repair. Openings span cell biology, electrophysiology, bioinformatics, hydrogel science and tissue engineering, combining stem cell biology, bioprinting and device engineering within a group of about 15 members.

Multielectrode Arrays · Calcium Imaging · Optogenetics +4

• Oxford
• On-site
• £40,178 – £48,700 pa
• Entry level
• Contract

Join a Gates Foundation-funded programme developing nanopore-based sensing platforms to detect volatile organic compounds in biological samples, part of the multidisciplinary Decoding Olfaction collaboration. The role combines chemical biology and biophysics to advance single-molecule sensing, with the goal of enabling personalised and continuous health monitoring. Multiple fixed-term postdoc positions are available in a collaborative academic and industrial environment.

• London
• Remote
• Senior

Responsible for the successful delivery of clinical studies at assigned investigator sites, acting as the primary point of contact for site management, monitoring, and study execution. Leads site preparation, initiation, routine monitoring, and close-out, conducting onsite and remote visits, source data review and verification, and CRF review. Works within a local study team for a key sponsor, using CTMS, eTMF and risk-based quality management, with travel across the UK and internationally.

CTMS · eTMF

• Reading
• Mid-level

Monitors clinical trial sites across selection, initiation, monitoring and close-out visits, ensuring compliance with GCP and ICH guidelines. Tracks recruitment, regulatory submissions, CRF completion and data queries, and maintains Trial Master File documentation. Works within a sponsor-dedicated team, liaising with sites and study team members.

• Oxford
• Lead · manages people

Lead a team of scientists developing novel biologic therapies for autoimmune disease, overseeing in vitro and in vivo pharmacology studies for lead and early discovery programs. Collaborate across immunology, protein engineering, translational medicine and biomarkers to deliver data packages for progression to development, while mentoring staff and contributing to INDs and patents.

• Uxbridge
• Hybrid
• Senior

An individual contributor role conducting non-interventional real-world data research for medical and HEOR teams across international markets. You will identify data sources, oversee statistical programming in R, and interpret and present findings to stakeholders. The position requires deep expertise in observational data analysis and offers hybrid working from Uxbridge.

R · GitHub · Claude +2

• London
• Hybrid · 2 days in office
• US$340,500 – US$567,500 pa
• Senior · manages people

Leads global development of a cancer vaccine asset from late-stage transition through approval and launch, acting as single point of accountability and chairing a cross-functional matrix Medicine Development Team spanning clinical, translational, regulatory, manufacturing and commercial. Drives strategy, go/no-go decisions and lifecycle plans for novel vaccine platforms such as mRNA and neoantigen-based therapies.

mRNA · Checkpoint Inhibitors

• Waltham, United States
• Hybrid · 2 days in office
• US$340,500 – US$567,500 pa
• Director · manages people

Leads global development of a cancer vaccine asset from late-stage transition through approval and launch, acting as single point of accountability across major markets. Builds and directs a matrix Medicine Development Team spanning clinical development, immunology/biomarkers, manufacturing, regulatory, safety, medical affairs and commercial, and represents the asset to senior governance boards.

mRNA · Personalized Vaccine Manufacturing · Checkpoint Inhibitors

• London
• On-site
• Permanent

Runs a high-throughput sample processing pipeline, performing DNA extraction, normalisation and library preparation on soil, faecal and other environmental samples. Operates automated liquid handling platforms such as Myra9, logs everything in Benchling LIMS, and carries out QC checks while supporting R&D protocol testing in a CL2 lab.

Benchling · Myra9 · Hamilton +2

• London
• On-site
• Senior
• Permanent

Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.

DoE

• Newcastle upon Tyne
• £30,180 pa
• Contract

Support ongoing research in the Murray lab on the mechanism of DNA in bacteria, using standard microbiology techniques, bacterial two-hybrid assays, and AlphaFold3 to predict protein-protein interfaces. The post also provides direct support to a cohort of undergraduate research students, working within a professional technical community under the Biosciences Institute Technical Manager.

AlphaFold3

• Newcastle upon Tyne
• £48,337 – £68,817 pa
• Senior
• Contract

Lead an independent research programme in transplant immunology, focusing on kidney transplantation injury and new therapies, while collaborating with nine senior investigators and the NIHR Blood and Transplant Research Unit. Contribute 0.2 WTE to undergraduate and postgraduate teaching and PhD supervision within the Translational and Clinical Research Institute.

Transplant Biobank