Biotechnology Jobs

413 jobs for “Operational Excellence”

Results

GSK logo

GSK · 10000+ people · Public

Senior Director, Cardiovascular and Metabolic Diseases, Clinical Pharmacology Modeling and Simulation

Save job
  • London
  • Hybrid
  • US$222,750 – US$371,250 pa
  • Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with digital medicine, imaging, modelling and data science partners. Reports into the Respiratory, Immunology & Inflammation Research Unit.

AI/ML · Digital Medicine · Translational Imaging +3

Last week
GSK logo

GSK · 10000+ people · Public

Senior Director, Cardiovascular and Metabolic Diseases, Clinical Pharmacology Modeling and Simulation

Save job
  • Stevenage
  • Hybrid
  • US$222,750 – US$371,250 pa
  • Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with digital medicine, translational imaging and modelling specialists. Based in Stevenage with a planned relocation to Cambridge, UK by early 2029.

MIDD · QSP · AI/ML

Last week
Ellison Institute of Technology logo

Ellison Institute of Technology · 501–1000 people · Non-profit

Postdoctoral Research Fellow (Zuercher Lab) - Generative Biology Institute

Save job
  • Oxford
  • On-site
  • Entry level
  • Permanent

Postdoctoral role in the Zuercher Lab at the Generative Biology Institute, working on genome synthesis and genetic isolation. Involves designing and troubleshooting experiments, analysing complex datasets with computational and statistical tools, publishing papers, and mentoring junior researchers. Based at Oxford Science Park in a new bespoke facility.

E. coli

7 months ago
Ellison Institute of Technology logo

Ellison Institute of Technology · 501–1000 people · Non-profit

Vector Design Lead - Plant Biology Institute

Save job
  • Oxford
  • On-site
  • Lead
  • Permanent

Leads vector design strategy for gene edited and transgenic crop programmes, covering expression cassette architecture, guide RNA modules, donor templates and multiplex editing configurations. Owns the design-to-vector-release process, including construct QC, sequence management, vendor workflows and handover packages for transformation teams. Builds an industrial-grade vector design capability for corn, wheat and other strategic species, with SOPs, LIMS/ELN tracking and mentoring of scientists.

ELN · LIMS

2 months ago
Roche logo

Roche · 10000+ people · Public

Field Service Engineer - Medical Diagnostics - North Region - Liverpool - Scotland

Save job
  • United Kingdom
  • Remote

Field-based role maintaining Roche diagnostic systems across molecular, tissue and serum work areas, using on-site support and remote diagnostics to resolve complex electro-mechanical faults. Duties include preventive maintenance, reporting, customer technical training and regulatory documentation, working within a UK customer-centric field support team.

Roche Diagnostics Systems

3 months ago

Moderna · 1001–5000 people · Late stage

Associate Director, CMC Regulatory Science - UK

Save job
  • London
  • Hybrid
  • Director

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and shape global regulatory approaches across cross-functional matrix teams.

MHRA · Generative AI

Clearance required 2 weeks ago

Thermo Fisher Scientific

Senior CTM, Internal Medicine (Dermatology, Nephrology, Cardiovascular, Women's Health, GI, Immunology, Rare Disease)

Save job
  • United Kingdom
  • Remote
  • Senior

Accountable for delivering clean clinical data on complex internal medicine trials within contract timelines, managing operational and quality aspects in compliance with ICH GCP. Leads clinical teams, develops monitoring tools and Trial Master File documentation, and may take on Lead CTM or Clinical Study Manager duties across therapeutic areas.

Outlook · Excel · Word

4 days ago

Relation Therapeutics

Snr Data Scientist, Computational Genomics/DNA Modelling

Save job
  • London
  • Senior
  • Permanent

Develops and benchmarks machine learning models for DNA sequence, regulatory elements and genetic variation, including variant effect prediction and representation learning. Integrates sequence-derived representations with transcriptomic, epigenomic and perturbational data to uncover disease mechanisms and support target prioritisation, working within the interdisciplinary Rosalind team.

Transformer · DNA Language Models · Genomic Foundation Models +2

4 months ago

Relation Therapeutics

Director, Clinical Pharmacology

Save job
  • London
  • Hybrid
  • Director
  • Permanent

Lead clinical pharmacology and pharmacometrics across a growing drug discovery portfolio, serving as the quantitative lead on cross-functional project teams. Apply MIDD, PBPK, population PK/PD and QSP modelling to translate nonclinical data into human dosing and trial design, spanning small molecules, biologics and novel platforms. Also manages CRO partnerships and authors regulatory submissions.

NONMEM · R · Monolix +3

3 months ago

Thermo Fisher Scientific

Senior CTM, Hematology/Oncology

Save job
  • United Kingdom
  • Remote
  • Senior · manages people

Accountable for delivering clean clinical data on time and within contract for low-to-moderate complexity haematology/oncology trials, managing operational and quality aspects in line with ICH GCP. Develops monitoring plans, CRF documents and Trial Master File content, tracks timelines and metrics, and may handle start-up, ethics submissions and project financials. Works within a team of CTMs, with travel to sites and a focus on radiopharmaceuticals, cell & gene therapy and CAR-T studies.

Outlook · Excel · Word

Last month

Pfizer · 10000+ people · Public

Sr Manager Data Scientist Supply Chain

Save job
  • Madrid, Spain
  • Hybrid
  • Senior

Builds, trains, deploys and maintains AI/ML models and automation tools for supply chain master data within Pfizer's Supply Planning Data Intelligence group. Work spans optimization algorithms, predictive models, generative AI/NLP, and autonomous data agents integrated with planning systems like Kinaxis, owning solutions from development through production handover.

scikit-learn · pandas · TensorFlow +7

6 days ago

Appcast Enterprise

Senior Director, Global Medical Director, Neuro-Oncology

Save job
  • London
  • Hybrid
  • Director · manages people

Leads the global and US Medical Affairs Neuro-Oncology team, owning medical strategy, evidence generation and launch planning for pipeline and marketed assets. Serves as a key interface between Medical Affairs and R&D, clinical development and commercial functions, representing regional insights in governance forums. Combines people management with hands-on execution across a complex matrix.

6 days ago

Autolus · 101–500 people · Series C

QA Associate

Save job
  • Stevenage
  • On-site
  • Entry level

Support GMP compliance in a multi-product cell and gene therapy facility, reviewing batch manufacturing and QC records, managing controlled documentation, and preparing patient-specific labels. Work with cross-functional teams on batch release, quality events and inspection readiness, on a Sunday–Wednesday shift pattern.

Last week

AstraZeneca · 10000+ people · Public

Senior Strategy Director (Senior Consultant) – Clinical Development – Evinova

Save job
  • Cambridge
  • Hybrid · 3 days in office
  • Director

Lead digital health strategy engagements with AstraZeneca R&D, top pharma and biotechs, shaping operating models and roadmaps across clinical development. Directs project teams on AI and digital solutions such as ePRO/eCOA, wearables and digital biomarkers, building business cases and tracking value realisation. Combines consulting, protocol design support and scaled implementation in a matrixed environment.

ePRO · eCOA · Wearables +1

Last week

IQVIA

Clinical Supply IRT Specialist

Save job
  • Reading
  • Hybrid
  • Mid-level

Supports clinical trials by designing, setting up and maintaining Interactive Response Technology (IRT) solutions, translating supply requirements into system specifications. Contributes to risk assessments, user acceptance testing and validation documentation, and advises study teams on IRT processes. Works with cross-functional global stakeholders on study startup, amendments and continuous improvement.

IRT · RTSM · IVRS +1

Last week

Get new Operational Excellence roles by email. One email a morning when new roles match. Stop any time.

Are you sure?