Jobs in London

Head of Medicinal Chemistry, Drug Design, London

Lead and strategically guide a team of 25 medicinal chemists in redefining drug discovery through deep integration with AI and machine learning. Shape the scientific direction of projects from hit identification to candidate nomination, while fostering collaboration across computational design, biology, and pre-clinical development teams. Drive innovation by challenging traditional paradigms and embedding an AI-first culture across the chemistry function.

Isomorphic Labs London, United Kingdom

On-site Permanent

Global Labelling Associate Director, Content (Cardiovascular, Renal & Metabolism)

This role involves developing and maintaining global labelling strategies and core documentation for pharmaceutical products in the cardiovascular, renal, and metabolism therapeutic areas. The individual will lead cross-functional discussions, ensure regulatory compliance, and translate clinical data into accurate, consistent labelling content for global markets. They will also support health authority interactions and contribute to risk assessment and audit readiness.

Novartis

Hybrid Permanent

Translational Medicine Expert – Gastroenterology, Associate Director

This role involves leading early-phase clinical development (Phase 1 and 2) of novel gastroenterology therapies, with a focus on inflammatory bowel disease (IBD). The Translational Medicine Expert will design clinical development plans, serve as medical lead for trials, and collaborate closely with research, biomarker, and late-phase development teams. The position requires strong scientific leadership, engagement with key opinion leaders, and active involvement in regulatory interactions.

Novartis London, United Kingdom £67,900 – £126,100 pa

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Senior Computational Biologist - Early Discovery Oncology

Drive target discovery and validation in precision oncology by integrating multimodal biological data (phenomics, transcriptomics, genomics, proteomics) to identify novel therapeutic targets. Collaborate with cross-functional teams to develop scalable computational methods and build compelling data packages that advance drug programs. Develop criteria for target nomination and support early translational strategies using AI-powered platforms.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Executive Director, Clinical Pharmacology/Pharmacometrics

This role involves leading clinical pharmacology and pharmacometrics strategies for rare disease and oncology programs, designing clinical studies, and interfacing with regulatory authorities. The position requires extensive experience in drug development, proficiency with modeling software, and collaboration with cross-functional teams.

Recursion United Kingdom

Clinical Supply Chain Manager

This role involves leading the end-to-end clinical supply chain strategy for global trials, managing demand forecasting, packaging, labeling, distribution, and inventory. You will work closely with cross-functional teams to ensure supply strategies align with trial milestones and commercial readiness, leveraging AI and advanced tools to optimize processes.

Recursion United Kingdom

Associate Director, Computational Biology – Early Discovery

Lead a team of computational biologists to identify and validate novel oncology targets using integrated phenomics, transcriptomics, genomics, and proteomics data. Develop and scale methods for target discovery in oncology and immunological diseases, collaborating closely with biologists, data scientists, and engineers. Drive data strategy and present findings to stakeholders to advance drug discovery programs.

Recursion United Kingdom

On-site Permanent

Vice President, Medical Affairs

The Vice President, Medical Affairs, will lead the development and execution of integrated medical strategies for Recursion's clinical portfolio, focusing on areas like oncology, rare disease, and immunology. Key responsibilities include building evidence-generation plans, engaging with key opinion leaders, and ensuring compliance with medical and regulatory standards.

Recursion United Kingdom